Examinando por Materia "Glutamina"

Mostrando 1 - 5 de 5

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Critical review: effect of oral glutamine supplementation on mucositis induced by cancer treatment of head and neck cancer
(Universidad Privada Norbert Wiener, 2022-08-16) Robles Vidal, Julio Rainiero; Palma Gutierrez, Edgardo Jhoffre
The information search was carried out in the Medline and Cochrane databases, finding 23 articles, 11 being selected, which have been evaluated by the CASPE critical reading tool, finally the selected article allowed us to conclude that oral glutamine supplementation reduces the incidence and severity of mucositis in adult patients with head and neck cancer
Acceso abierto
Critical review: supplementation with parenteral glutamine in critical adult patients
(Universidad Privada Norbert Wiener, 2022-12-29) Zeballos Alcalde, Cinthia Mónica; Inocente Camones, Miguel Angel
This secondary research, titled as a critical review: 'Parenteral glutamine supplementation in critically ill adult patients,' aimed to determine the improvement in clinical outcomes (hospital infections, mechanical ventilation days, and ICU length of stay) in critically ill adult patients who received parenteral glutamine supplementation. The clinical question was: Does parenteral glutamine supplementation improve clinical outcomes (hospital infections, mechanical ventilation days, and ICU length of stay) in critically ill adult patients? The Evidence-Based Nutrition (NuBE) methodology was used. Information was searched in Science Direct, PubMed, HINARI, Lilacs, Latindex, Scielo, ERIHPLUS, Dialnet, Redalyc, and Cochrane, finding 62 articles, of which 21 were selected and evaluated using the CASPe critical appraisal tool. Ultimately, the systematic review titled 'Parenteral glutamine supplementation in critical illness: a systematic review' was selected, with a level II evidence and a Strong Recommendation Grade according to the researcher's expertise. The critical commentary concluded that there is sufficient evidence to affirm the beneficial effect of intravenous glutamine supplementation in reducing hospital mortality, infectious complications, mechanical ventilation days, and ICU length of stay.
Acceso abierto
Critical review: the effect of glutamine-probiotic supplementation on intestinal permeability of surgical patients with gastrointestinal cancer
(Universidad Privada Norbert Wiener, 2022-03-25) Lo Tayraco, Jessica Alexandra; Bohórquez Medina, Andrea Lisbet
The present secondary research titled as a critical review: The effect of glutamine or probiotic supplementation on the intestinal permeability of surgical patients with gastrointestinal cancer, aimed to determine the effect of glutamine or probiotic supplementation on the intestinal permeability of surgical patients with gastrointestinal cancer. The clinical question was: What is the effect of glutamine or probiotic supplementation on intestinal permeability in surgical patients with gastrointestinal cancer? The Evidence-Based Nutrition (NuBE) methodology was used. An information search was carried out in PUBMED, SCOPUS, SCIENCE DIRECT, where 47 articles were found, of which 5 were selected to be evaluated by the CASPE Critical Reading Tool, finally selecting the Randomized Clinical Trial titled “Addition of probiotics to glutamine therapy as intestinal barrier protection for severe surgical patients”, which has a level of evidence AI and Strong Recommendation Grade, according to the researcher's experience. The critical commentary concluded that the simultaneous administration of probiotics and glutamine has a synergistic and protective effect on intestinal barrier function and in reducing intestinal permeability.
Acceso abierto
Revisión crítica: efecto de la suplementación oral con glutamina en la severidad de mucositis de pacientes con cáncer de cabeza y cuello
(Universidad Privada Norbert Wiener, 2025-09-11) Romero Hernández, Diego José; Bohórquez Medina, Andrea Lisbet
La mucositis oral constituye una complicación frecuente en pacientes que reciben radioterapia y quimioterapia. Se ha propuesto que la glutamina oral puede tener un efecto beneficioso al disminuir la severidad de la mucositis oral y mitigar otras complicaciones asociadas a la misma. El propósito de la investigación fue evaluar el efecto de la suplementación oral con glutamina en la severidad de mucositis en pacientes con cáncer de cabeza y cuello. La recopilación de información se llevó a cabo en las bases de datos PubMed, ScienceDirect y Scopus, identificándose un total de 29 artículos. De estos, 10 fueron sometidos a evaluación empleando los criterios de la herramienta de lectura crítica CASPe. Finalmente, se seleccionó una revisión sistemática y metaanálisis que, según la experiencia del investigador, poseía un nivel de evidencia A1 y un grado de recomendación Fuerte. Al realizar la discusión crítica se determinó que el uso de glutamina oral contribuye a disminuir la severidad de la mucositis oral inducida por radiación de forma estadísticamente significativa, sin efectos adversos clínicos para el paciente. Sin embargo, aún existen limitaciones con respecto a la dosis, frecuencia y administración. Por consiguiente, se requieren investigaciones adicionales que permitan superar las restricciones actuales de esta estrategia dieto terapéutica para el manejo futuro de la mucositis oral en pacientes oncológicos.
Acceso abierto
Use of Glutamine in Cancer Patients
(Universidad Privada Norbert Wiener, 2018-11-15) Arquinio Regalado, Katherine Kathiuska; Mauricio Alza, Saby Marisol
The use of glutamine as part of the nutritional support received by cancer patients. The present secondary research entitled as a critical review: Use of Glutamine in oncological patients, aimed to determine the effectiveness of glutamine in oncological patients. The clinical question was: How effective and safe is glutamine in cancer patients? The Evidence-Based Nutrition (NuBE) methodology was used. The search was carried out in Pub Med, Science Direct, Scielo, Google Scholar, Elsevier Scopus, Cochrane, Springer, finding 149 Articles, 40 being selected that have been evaluated by the CASPE tool, selecting the Clinical Trial entitled Effects Of Oral Glutamine on Inflammatory and Autophagy Responses in Cancer Patients Treated With Abdominal Radiotherapy: A Pilot Randomized Trial, which has a level of evidence I and Grade of recommendation Strong, according to the researcher's expertise. The critical comment allowed us to conclude that glutamine has an effect on reducing the inflammatory response caused by the treatment; the effect must continue to be studied with a more rigorous methodology and on a larger scale.