Examinando por Materia "Hipotermia Inducida"

Mostrando 1 - 4 de 4

Acceso abierto
Effectiveness of induced therapeutic hypothermia for neuroprotection in newborns with hypoxic-ischemic encephalopathy
(Universidad Privada Norbert Wiener, 2018-12-16) Asencios Nieto, Yeny Elizabeth; Cabrera Andía, Macedonia; Uturunco Vera, Milagros Lizbeth
MATERIAL AND METHOD: The systematic review of the 10 articles on the effectiveness of induced therapeutic hypothermia for neuroprotection in newborns with hypoxic ischemic encephalopathy were found in the following databases: Cochrane, Scielo and Pubmed. Of the 10 articles reviewed, 60% (6/10) correspond to the methodological design of systematic reviews and/or meta-analysis, 30% (3/10) are randomized clinical trials and 10% (1/10) are studies cross. All of them were analyzed according to the Grade scale to determine their strength and quality of evidence. RESULTS: 100% of the reviewed articles are conclusive, these are supported by 6 systematic reviews, 3 randomized clinical trials and 1 cross-sectional study, all of which suggest the use of induced therapeutic hypothermia is the best alternative for the hospital management of newborns. with hypoxic ischemic encephalopathy. However, some of these authors suggest conducting further follow-up studies to verify the effectiveness of this intervention in the long term. CONCLUSIONS: Of the 10 articles reviewed, 100% (10/10) show the effectiveness of induced therapeutic hypothermia in neuroprotection in newborns with hypoxic ischemic encephalopathy, because it reduces neurological damage, sequelae and a decrease in the mortality rate. .
Acceso abierto
Effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients
(Universidad Privada Norbert Wiener, 2017-12-03) Félix Saavedra, Flor de María; Flores Chipana, Ciprian; Pretell Aguilar, Rosa Maria
Objective: To systematize the evidence on the effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients. Methodology: An observational and retrospective systematic review, where the search was restricted to full-text articles, and the selected articles underwent critical reading using the GRADE evaluation system to determine their level of evidence. In the final selection, 10 articles were chosen, of which 60% were meta-analyses and 20% were systematic reviews with high evidence quality and strong recommendation strength. Of these, 30% (3) were from China, 10% (1) from Austria, 10% (1) from the United States, and 10% (1) from India. Regarding systematic reviews, 10% (1) were from the USA and 10% (1) from China. With 20% being clinical trials and cohort studies with moderate evidence quality and weak recommendation strength, 10% (1) were from Portugal and 10% (1) from the United States. Results: Among the reviewed evidence, 70% affirm that therapeutic hypothermia contributes to neuroprotection in post-cardiac arrest patients, while 30% suggest that therapeutic hypothermia does not provide any benefit in neurocritical post-cardiac arrest patients. Conclusions: The best-reviewed evidence demonstrates that therapeutic hypothermia reduces neurological damage after cardiac arrest in neurocritical patients.
Acceso abierto
Effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients
(Universidad Privada Norbert Wiener, 2017-12-03) Félix Saavedra, Flor de María; Flores Chipana, Ciprian; Pretell Aguilar, Rosa Maria
Objective: To systematize the evidence on the effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients. Methodology: An observational and retrospective systematic review, where the search was restricted to full-text articles, and the selected articles underwent critical reading using the GRADE evaluation system to determine their level of evidence. In the final selection, 10 articles were chosen, of which 60% were meta-analyses and 20% were systematic reviews with high evidence quality and strong recommendation strength. Of these, 30% (3) were from China, 10% (1) from Austria, 10% (1) from the United States, and 10% (1) from India. Regarding systematic reviews, 10% (1) were from the USA and 10% (1) from China. With 20% being clinical trials and cohort studies with moderate evidence quality and weak recommendation strength, 10% (1) were from Portugal and 10% (1) from the United States. Results: Among the reviewed evidence, 70% affirm that therapeutic hypothermia contributes to neuroprotection in post-cardiac arrest patients, while 30% suggest that therapeutic hypothermia does not provide any benefit in neurocritical post-cardiac arrest patients. Conclusions: The best-reviewed evidence demonstrates that therapeutic hypothermia reduces neurological damage after cardiac arrest in neurocritical patients.
Acceso abierto
Neuroprotective efficacy of therapeutic hypothermia in patients post-cardiac arrest
(Universidad Privada Norbert Wiener, 2018-07-08) Celis Garcia, Erika Mabel; Calsin Pacompia, Wilmer
Systematic observational, retrospective and quantitative review, where the GRADE evaluation system was used to identify the degree of evidence and the strength of recommendation of each article found in the following databases: Scielo, Pubmed, Elvesier, Medline, BVS. 60% (n=6/10) are systematic reviews, 10% (n= 1/10) experimental studies, 20% (n= 2/10) case control, 10% (n= 1/10) cohort study . Likewise, 70% (n=7/10) are of high quality with a strong strength of evidence and 30% (n=3/10) are of moderate quality with a weak strength of evidence. Originating 40% in the USA, 20% in Spain, 10% in Austria, 10% in Canada, 10% in the Czech Republic, and 10% in Germany. Results: all the articles systematically reviewed (n=10/10) indicate a neuroprotective effectiveness of therapeutic hypothermia in post-cardiorespiratory arrest patients. Conclusions: 7/10 of the articles show an improvement in the neurological probabilities of the patients, another 7/10 a better survival to hospital discharge and 4/10 show that there is a decrease in mortality and an improvement in the morbidity of the patient. patient.