Examinando por Materia "Hyperphosphatemia"

Mostrando 1 - 3 de 3

Acceso abierto
Comparative efficacy and safety of phosphate binders in hyperphosphatemic patients with chronic kidney disease.
(Universidad Privada Norbert Wiener, 2022-05-30) Zavaleta Gavidia, Rosa Haydee; León Cáceres, Johanna del Carmen
Phosphorus binders reduce the absorption of phosphorus obtained from the diet in the gastrointestinal tract. Critical review entitled: The use of phosphorus binders reduce hyperphosphatemia in patients over 18 years of age with chronic kidney disease and on hemodialysis, the objective was to prepare the professional critical commentary, according to the clinical studies related to the subject, with the clinical question: Does the use of phosphorus binders reduce hyperphosphatemia in patients over 18 years of age with Chronic Kidney Disease and on HD?, the method based on evidence from NUBE was used. The search for information was carried out in PUBMED, SCIELO, SCIENCE DIRECT, finding 344 articles, of which 10 articles were selected, evaluated by the critical reading tool CASPE, finally, a Meta-analysis entitled comparative efficacy and safety of phosphorus binders in patients with hyperphosphatemia with chronic kidney disease was selected, with level of evidence AII and Strong Recall Grade; Based on the researcher's experience, critical commentary determined that iron-based phosphate binding agents were the preferred agents in terms of both efficacy and safety.
Acceso abierto
Efficacy of lanthanum carbonate versus sevelamer in the management of hyperphosphatemia in adult patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2019-09-22) Bardales Ríos, Silvia; Aguilar Ferroñán, Lizbeth Nataly; Rivera Lozada de Bonilla, Oriana
Objective: To systematize the evidence on the efficacy of lanthanum carbonate versus sevelamer for managing hyperphosphatemia in adult patients with chronic kidney disease. Materials and Methods: The 10 bibliographic reviews were found in the PubMed and Epistemonikos databases, all of which were of high quality. 50% are randomized trials, 30% are systematic reviews, and 20% are meta-analyses. The results come from the USA (60%), China (20%), and Japan (20%). Results: According to the evidence, 70% demonstrate that lanthanum carbonate is more effective than sevelamer for managing hyperphosphatemia in patients with chronic kidney disease. 10% showed minimal significant difference, 10% found that sevelamer hydrochloride was more effective than lanthanum carbonate, and 10% found that both medications are effective. Conclusion: Seven out of 10 articles demonstrate that lanthanum carbonate is more effective than sevelamer in managing hyperphosphatemia, 1 out of 10 showed minimal significant difference, 1 out of 10 found that sevelamer hydrochloride is more effective, and 1 out of 10 found that both medications are equally effective.
Acceso abierto
Systematic Review: Nutritional Treatment of hyperphosphatemia in patients with CKD in Replacement Therapy.
(Universidad Privada Norbert Wiener, 2022-03-04) Reyes Osorio, Milagros Anatolia; Dávila Córdova, Jennifer Estefania
Introduction: Chronic kidney disease has become a public health problem that affects 10% of the Peruvian population. Hyperphosphatemia is related to a high risk of death from cardiovascular disease in patients with CKD; For this reason, it is of utmost importance to initiate therapeutic strategies to reduce serum concentrations of this electrolyte. The main objective of this research work is to demonstrate that nutritional treatment is effective in reducing hyperphosphatemia levels in patients with CKD on replacement therapy. Type and design: Bibliographic review. Population and sample: 17 scientific articles. Data collection procedure: Data search in Scielo, Dialnet, Google scholar, Pubmed, Medline, and Academia.edu. Analysis technique: Evaluation of validity, quality, strength of recommendation of scientific evidence and usefulness of the findings. Discussion: 64.7% of the scientific articles reviewed demonstrated a significant reduction in blood phosphorus levels after some type of nutritional intervention. 35.3% showed that there were no significant results or no results. The results improved when the intervention was carried out individually (nutritional counseling) compared to educational sessions that were carried out in groups.