Examinando por Materia "Ivermectin"

Mostrando 1 - 11 de 11

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Cumplimiento de buenas practicas de prescripción y determinacion de interacciones medicamentosas con ivermectina en tiempos de COVID-19 en recetas médicas atendidas en la farmacia del Centro de Salud Unidad Vecinal N° 3 – mayo a diciembre 2020
(Universidad Privada Norbert Wiener, 2022-04-27) Curo Guevara, Sara Elizabeth; Mendoza Baldeón, Gonzalina; Félix Véliz, Luis Miguel Visitación
The global COVID-19 health emergency has created a need to find medications to help treat and combat it. In this context, Ivermectin was established as an option frequently recommended by doctors, making it essential that it be correctly prescribed and dispensed to patients. Objective: To determine drug interactions in ivermectin prescriptions filled at the pharmacy of Neighborhood Health Center No. 3 from May to December 2020, in compliance with good prescribing practices. Methodology: This was a descriptive study, supported by the use of forms for data collection from 204 prescriptions at the Health Center's pharmacy. Results: Prescriber data was completed in over 95% of prescriptions, and patient data had even higher completion rates, always exceeding 97%. Medication data completion surpassed 98%. Drug interactions were found in 81 prescriptions, all of which were of moderate severity with a potential clinical manifestation. No pharmacological follow-up was performed to determine a real clinical manifestation. Furthermore, all 81 (100%) of the interactions were potential pharmacokinetic interactions, and none were potential pharmacodynamic interactions. Conclusion: Although good prescribing practices were well implemented, a key finding is that potential drug interactions were present in the patients' treatments, as identified through information searches.
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Estudio de la estabilidad acelerada de una formulación de solución oral de ivermectina 6 mg/ml, Lima 2021–2022
(Universidad Privada Norbert Wiener, 2023-09-05) Gutiérrez Shimabukuro, Astrid Carolina; Pertuza Izquierdo, Cristian; Cano Pérez, Carlos Alfredo
The accelerated stability study of a formulation is important to determine the physical, chemical, and microbiological stability of the medication before commercialization. Therefore, the objective of this research was to conduct an accelerated stability study of a 6 mg/mL Ivermectin Oral Solution formulation. Method: The study was deductive, basic, and experimental, conducted on three pilot batches subjected to chemical, physical, and microbiological analyses. Results: The 6 mg/mL Ivermectin Oral Solution formulation maintained its organoleptic characteristics throughout the study period. Its delivery volume was no less than 95% of the declared amount, its pH ranged between 6.22 - 6.73, and its specific weight ranged between 1.0372 - 1.0909. In the identification test, it tested positive, and its concentration ranged from 5.40 to 6.60 mg/mL. Additionally, the total aerobic microorganism count (TAMC) was ≤102 cfu/mL, the total combined count of filamentous fungi and yeasts was ≤101 cfu/mL, and in the specific microorganism test, Escherichia coli was absent per mL. Conclusion: The 6 mg/mL Ivermectin Oral Solution formulation meets the physical, chemical, and microbiological specifications.
Acceso abierto
Estudio de las formulaciones magistrales de ivermectina elaboradas en oficinas farmacéuticas en Lima, utilizadas en el tratamiento de la pandemia de COVID-19 setiembre a noviembre del 2020
(Universidad Privada Norbert Wiener, 2021-07-23) Martel Sheputt, Cecilia Inés; Vidal Tarazona, Bertha; Parreño Tipián, Juan Manuel
The general objective was to determine the physicochemical parameters that would be used for the study of Ivermectin magistral formulations prepared in pharmaceutical offices in Lima and utilized in the treatment of the COVID-19 pandemic from September to November 2020. The following methodology was used: The research type, according to its function, is basic, with a qualitative and quantitative approach and an applicative scope with a quasi-experimental design. The technique utilized was a data collection form for the variables. The population and sample comprised Ivermectin magistral formulations from public and private institutions. The main conclusion was to determine the physical and chemical parameters present in the Ivermectin magistral formulations. Based on the USP 42 methodology as a reference, the analytical tests concluded that they do comply with the parameters established within the general chapters of USP 42.
Acceso abierto
Factores asociados a la automedicación de ivermectina para COVID-19 en pobladores de 18 a 60 años, distrito Carmen de la Legua Reynoso, Callao 2021
(Universidad Privada Norbert Wiener, 2022-08-25) Martinez Yalle, Geraldine Araceli; Alvarado Chávez, Britt
Currently, the population has been affected by the SARS-CoV-2 virus, also known as COVID-19, which became a pandemic. The objective of this study was "To determine the factors associated with the self-medication of ivermectin for COVID-19 among people aged 18 to 60 in the district of Carmen de la Legua Reynoso, Callao 2021." Methodology: The study was quantitative, cross-sectional, descriptive, and non-experimental, involving 380 residents. Data collection was carried out using a survey and a Likert scale questionnaire. Results: The 40-59 age group (38.3%) presented a high level of self-medication, and 19.1% exhibited high behavioral levels of self-medication. Young people (8.2%) and housewives presented high behavioral levels of self-medication. Among those who stated they acquire their medicine from a drugstore or pharmacy, the percentage of residents with high behavioral levels of self-medication was 14.5%. The most frequent attitudinal level of self-medication among young people aged 19-29 years was medium (41.5%). The private healthcare system had the lowest percentage of residents with high attitudinal levels of self-medication (12.8%). Conclusion: Self-medication with ivermectin for COVID-19 is associated with age and the place of acquisition. The behavioral aspect of self-medication is associated with age, occupation, and place of acquisition. The attitudinal aspect of self-medication with ivermectin for COVID-19 is associated with both age and the healthcare system.
Acceso abierto
Factores asociados a la automedicación de ivermectina para COVID-19 en usuarios que acuden a dos establecimientos farmacéuticos en el Cercado de Lima 2021
(Universidad Privada Norbert Wiener, 2023-01-19) Callosani Huanacuni, Bertha Alexandra Aylin; Sotelo Lazo, Katherine Sidia; Juárez Moreyra, Enrique
The COVID-19 virus emerged in the city of Wuhan, rapidly spreading across China and overwhelming global healthcare systems, leading to the collapse of public health services. In Peru, a state of emergency was declared in March 2020, which included mandatory lockdowns, border closures, and the suspension of academic activities. Due to the health crisis, existing medications were repurposed to treat and prevent COVID-19, with ivermectin being one of the most widely used. Objective: To determine the factors associated with self-medication with ivermectin for COVID-19 among users visiting two pharmaceutical establishments in Cercado de Lima, 2021. Methodology: A quantitative approach was used with an observational-cross-sectional design. The study population consisted of 385 users who attended two pharmaceutical establishments in Cercado de Lima. A survey divided into five dimensions aligned with the variables was used as an instrument, featuring closed questions and multiple-choice answers. Results: The majority of respondents were female (56.4%), aged between 26 and 35 years. Most had only secondary education (39.5%) and were insured under the SIS program (43.6%). Social media was the main source of information about COVID-19, and 66% of respondents reported self-medicating with ivermectin. Conclusion: It was concluded that the social factor is directly associated with self-medication with ivermectin.
Acceso abierto
Factores culturales, biológicos y automedicación de ivermectina en tiempos de pandemia en trabajadores del mercado Gambetta del pueblo joven Néstor Gambetta Baja distrito de la Provincia Constitucional del Callao. 2021
(Universidad Privada Norbert Wiener, 2021-11-30) Contreras Ponce, Daisha Raquel; Puma Paucar, Yuli; Guadalupe Sifuentes de Posadas, Luz Fabiola
The objective of this research was to determine the relationship between cultural and biological factors and self-medication with Ivermectin during the pandemic among workers at the Gambetta market. Method: This study used a quantitative approach, a basic type, a non-experimental design, and a correlational level. The sample consisted of 213 people over 18 years old, to whom a self-developed, expert-validated instrument was applied. The technique was a 16-question survey. For statistical analysis, SPSS version 25 and the Chi-squared test of independence were used. Results: A significant statistical association was found between the "learned habits" and "symptoms" dimensions, specifically between the indicators for drug acquisition and unwanted symptoms. An association was also found between the "need for consumption" and "frequency of use" dimensions, linking the reason for self-medication with the duration of self-medication. Furthermore, an association was found between the "media" and "frequency of use" dimensions, linking media influence with the quantity consumed. However, no association was found between the "age group" and "complementary medication" dimensions. Conclusion: An association exists between cultural factors and self-medication with Ivermectin, but no significant association was found between the biological factor and self-medication with Ivermectin among workers at the Gambetta market in the Néstor Gambetta Baja shantytown during the pandemic.
Acceso abierto
Ivermectina, determinación de su eficacia y seguridad en COVID-19
(Universidad Privada Norbert Wiener, 2023-03-11) Fernandez Ramos, Joselin Victoria; Rodriguez Navarro, Norma; Castillo Soto, Pedro Félix
According to the World Health Organization, which was one of the first organizations to provide information about the situation in China, the virus began claiming its first victims. Once the initial symptoms of COVID-19 were published, the virus started spreading exponentially, leading many countries to implement drastic measures, such as locking down people regardless of whether they showed symptoms of the virus. In response to this issue, industries began a race to find a cure to alleviate the symptoms of COVID-19. One of the medications used at the time was Ivermectin, which began to be administered without solid scientific evidence. Objective: To determine the safety and efficacy of Ivermectin as a potential treatment for patients testing positive for COVID-19. Methodology: Our research focuses on various informational sources, employing a qualitative or descriptive approach. Results: For this research project, results were defined based on the quality of the findings, which included information on Ivermectin and its evaluation as a treatment for the virus. The outcome revealed that evidence supporting its use was limited.
Acceso abierto
Nivel de conocimiento de ivermectina y tratamiento de COVID-19 en usuarios de cuatro oficinas farmacéuticas de Chota, Cajamarca - 2022
(Universidad Privada Norbert Wiener, 2022-05-19) Quispe Rojas, Cinthya Paola; Rojas Wisa, Oscar Favio
The objective of the research was to determine the relationship between the level of knowledge of Ivermectin and the level of knowledge of COVID-19 treatment among users visiting four pharmaceutical offices in Chota, Cajamarca, in 2022. Method: The hypothetical-deductive method was used, with a quantitative approach, a basic study type, and a non-experimental descriptive correlational design. The sampling was simple random probabilistic. The sample consisted of 132 users who visited four pharmaceutical offices. The technique was a survey, and the instrument was a 20-closed-question questionnaire. Results: Of the 132 users, 59.8% were aged 18–28, and the majority were female (63.3%). Regarding knowledge of Ivermectin, 75% were unaware of its therapeutic and pharmacological indications, 60% were unaware of its pharmacological properties, and more than 50% were unaware of the adverse reactions. 70% had correct answers regarding COVID-19 prevention and transmission, and more than 69.7% gave correct answers for the clinical picture of COVID-19. However, 78.8% were unaware of the pathophysiology of COVID-19. Overall, 50.8% had a low level of knowledge about Ivermectin, and 51.5% had a good level of knowledge about COVID-19 treatment.
Acceso abierto
Prevalencia de la automedicación con Ivermectina en tiempos de pandemia por COVID-19 en usuarios de la botica Mifarmac en el distrito de San Juan de Lurigancho – Lima Metropolitana, primer semestre 2021
(Universidad Privada Norbert Wiener, 2021-10-06) Quillca Sanchez, Raquel; Del Castillo Vargas, Gloria; Caldas Herrera, Emma
Self-medication increased during the COVID-19 pandemic, possibly due to the panic generated in the population, the high cost of medications, and limited access to health centers. The objective was to determine the prevalence of self-medication with Ivermectin during the COVID-19 pandemic among users of the MIFARMAC drugstore in the San Juan de Lurigancho district, Metropolitan Lima, in the first semester of 2021. Methodology: This was a descriptive-observational study where the instrument was a validated questionnaire applied to 385 users. Results: A high prevalence of self-medication with Ivermectin (62.33%) was found. 59.2% of users knew about its use, 36.7% consumed it once a month, and the most consumed pharmaceutical form was drops (94.6%). Regarding unwanted effects, 66.3% reported no major effects. 76.7% knew about the origin of COVID-19 and 89.7% knew its symptoms. 86.7% were aware of preventive measures, and 95.8% knew the concept of self-medication. Conclusion: The prevalence of self-medication with Ivermectin during the COVID-19 pandemic is high, at 62.33% of the total sample.
Acceso abierto
Uso de ivermectina para terapia del COVID-19 por los usuarios de la botica Reyesfarma del distrito de Lurín – Lima Metropolitana, primer semestre 2021
(Universidad Privada Norbert Wiener, 2022-01-17) Lino Fuentes, Erika Patricia; Reyes Altamirano, Deyvis Alvaro; Ramos Jaco, Antonio Guillermo
The objective of this research was to determine the characteristics of ivermectin use for COVID-19 therapy among users of the REYESFARMA drugstore in the Lurín district of Metropolitan Lima during the first semester of 2021. Method: The study used a quantitative approach with a basic type, a non-experimental design, and a correlational level in accordance with the scientific research procedure. The population consisted of 320 people, and a sample of 153 was used, to whom a questionnaire was applied via a survey. For statistical analysis, SPSS Version 25.0 and the test of symmetric measures and contingency coefficient were used. Results: A very strong positive association was found between the variable of ivermectin use and the intervening variable of COVID-19 therapy, with a contingency coefficient of 0.766 and a p-value of 0.001, which is less than 0.05. Conclusion: The characteristics of ivermectin use for COVID-19 therapy were determined, with 71.9% of users having a medium level of use with antiviral action, 15.7% having a strong antiviral action level of use, and 12.4% having a high antiviral action level of use.
Acceso abierto
Uso Indiscriminado de ivermectina para COVID-19 en usuarios atendidos en boticas ubicadas en los alrededores de Lecaros en Puente Piedra, marzo – 2021
(Universidad Privada Norbert Wiener, 2021-08-09) Aguayo Ariza, Milagros Magaly; Guia Campos, Grecia Myriam; Parreño Tipián, Juan Manuel
Introduction: Currently, COVID-19 is a major global public health problem due to its infective capacity and high pathogenicity. Objective: This study aimed to demonstrate how COVID-19 is related to the indiscriminate use of ivermectin among users served at drugstores in the vicinity of Lecaros, Puente Piedra, in March 2021. Method: The research used an inductive method, with a quantitative approach, a basic type, and a descriptive, correlational, and cross-sectional design. The instrument used was a questionnaire, which was applied to 380 users who visited drugstores in the Lecaros area. Results: It was found that 61.7% reported a high level of self-medication, and 65.1% reported a high consumption of ivermectin. A high presence of symptoms was found at 65.4%. Furthermore, 44% undertook a high level of treatment, and 60.9% engaged in a high level of prevention. Conclusions: It was demonstrated that COVID-19 is related to the indiscriminate use of ivermectin.