Examinando por Materia "Laboratorios clínicos"

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    Status of the role of clinical laboratories in the assessment of dysmorphic red blood cells in urinary sediment, Lima - 2023
    (Universidad Privada Norbert Wiener, 2023-10-01) Benites Ricra, Miguel Angel; Saldaña Orejón, Italo Moisés
    Hematuria is defined by the presence of red blood cells in elevated quantities observed microscopically in the urinary sediment. The dysmorphic (abnormal) characteristic of the red blood cell in urine is a result of its passage through the glomerulus, indicating glomerular-origin hematuria. The initial diagnostic test should include microscopic examination of urinary sediment, the count of red blood cells observed per mm3, and the correct identification of the red blood cell morphology, either normal (biconcave) or dysmorphic with deterioration or deformation, such as vesicles or blisters on the red blood cell membrane, which indicates glomerular-origin hematuria. Currently, only international studies have shown the lack of standardization in methods for detecting and quantifying hematuria, and even difficulties in distinguishing non-glomerular hematuria from glomerular hematuria, as well as recognizing and categorizing dysmorphic red blood cell morphology, leading to discrepancies in clinical laboratories and suboptimal diagnoses.