Examinando por Materia "Lymphocyte Count"

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Acceso abierto
Association of the neutrophil/lymphocyte index with the mortality of covid-19 patients at Hospital II Clínica Geriátrica San Isidro Labrador October 2020 – February 2021. Lima – Peru
(Universidad Privada Norbert Wiener, 2023-11-19) Alcarraz Mondalgo, Katherine Ivonne; Huamán Cárdenas, Victor Raul
The neutrophil-lymphocyte index is a hematological marker previously studied for inflammation in various diseases. In COVID-19 infection, the NLR has gained significance for determining severity and predicting mortality in infected patients. This thesis seeks to associate the NLR with the mortality of COVID-19 patients at the San Isidro Labrador Geriatric Clinic, Lima, from October 2020 to February 2021. The study evaluated 180 patients diagnosed with COVID-19, using hematological values to determine the NLR and seek associations using SPSS. It found that 72.8% of deceased patients were male, with an average age of 76.1 years. The odds ratio was calculated, revealing that patients with an NLR >7 had a 9.7 times higher risk of death. The logistic regression analysis found that patients with elevated NLR had 1.5 times higher mortality risk (p: 0.000). It was concluded that NLR is a good predictor of mortality in COVID-19 infected patients.
Acceso abierto
Characteristics of the Neutrophil Lymphocyte Index in the Acute Phase of Outpatient Covid-19 patients at the Conde de la Vega Baja health center in Lima, Peru, December 2020- January 2021
(Universidad Privada Norbert Wiener, 2022-04-07) Roca Vidal, Christian Alonso; Huamán Cárdenas, Victor Raul
COVID-19 causes an inflammatory pulmonary response triggered by the cytokine storm. The clinical laboratory has contributed with analyses that help monitor patient progression, with the neutrophil-lymphocyte index (NLR) providing significant prognostic value, as it is associated with lymphopenia due to lymphocyte migration towards the lungs. The aim of this study was to determine the characteristics of the neutrophil-lymphocyte index in the acute phase of ambulatory COVID-19 patients at the Conde de la Vega Baja Health Center in Lima, Peru, from December 2020 to January 2021. This was a descriptive, observational (non-experimental), and cross-sectional study involving 30 patients with non-probabilistic convenience sampling. Participants had a recent reactive rapid test result for IgM or a positive molecular or antigen test, and did not have hematological or infectious diseases. The only measured variable was the neutrophil-lymphocyte index, and blood sample collection and processing followed established protocols. Data analysis was performed using Excel 2016, with tables and graphs for means and medians.
Acceso abierto
Concentración de Carga Viral y Recuento de Linfocitos T CD4+ en pacientes recién diagnosticados con el Virus de Inmunodeficiencia Humana en una clínica particular en Lima Metropolitana, 2021-2022
(Universidad Privada Norbert Wiener, 2024-10-30) Espinoza Guillen, Joselyn Alejandra; Champa Guevara, Cesar Alfonso
OBJETIVO: Identificar la concentración de carga viral y recuento de linfocitos T CD4+ que presentan las personas recién diagnosticadas con el VIH en una clínica particular en Lima Metropolitana, mayo 2021-mayo 2022. MATERIALES Y METODOS: El estudio fue de tipo aplicado, descriptivo, de método y diseño deductivo, observacional y de corte transversal, conformado por 241 pacientes recién diagnosticados con el virus de inmunodeficiencia humana que cumplieron con los criterios de inclusión, se utilizó como método el análisis documental de las historias clínicas archivadas, como instrumento una ficha de recolección de datos y se creó una hoja de cálculo virtual. RESULTADOS: La concentración de carga viral se encontró elevada en el 52% de los pacientes (>100000 copias/ml) y el recuento de linfocitos T CD4+ se encontró disminuido (<350 cél/μL) en el 63% de los pacientes. Asimismo, se encontraron principalmente en el estadio 3 y 4, representando el 30 y 33% respectivamente. Además, los factores demográficos asociados con mayores casos de diagnóstico tardío fueron: las personas adultas con el 64,4%, sexo femenino con 81,8% y orientación sexual heterosexual con 75,9%. CONCLUSIÓN: Se concluyó que los pacientes recién diagnosticados con el VIH presentaron una carga viral elevada y un recuento de linfocitos T CD4+ disminuido.
Acceso abierto
Diagnostic correlation in the differential leukocyte count between the GENRUI KAT-40 automated system and peripheral film in the private medical office
(Universidad Privada Norbert Wiener, 2024-05-05) Fernández Becerra, Juliana Elizabeth; Moya Salazar, Jeel Junior
The use of automated systems for blood analysis offers efficiency and speed in obtaining results, but it is essential to ensure the precision and reliability of these data. This study aims to compare the results of the automated leukocyte differential count obtained using the GENRUI KT-40 automated system with those from manual peripheral smear examination.
Acceso abierto
Neutrophil/Lymphocyte index and procalcitonin index in patients with sepsis hospitalized in a private clinic, Lima 2021
(Universidad Privada Norbert Wiener, 2023-05-07) Limaymanta Cárdenas, Milagros del Rosario; Avelino Callupe, Paul Fortunato
Sepsis is one of the leading causes of high hospitalization rates and mortality in intensive care units for both adults and newborns. Sepsis diagnosis is often delayed due to symptom similarities with other conditions. Various diagnostic methods, such as procalcitonin levels and blood culture (hemoculture), are used, but not all healthcare centers have access to these tests due to shortages of materials and high costs. Thus, there is a need to explore the neutrophil/lymphocyte ratio as a low-cost alternative and easy-to-access marker for presuming sepsis diagnosis.
Acceso abierto
Relationship between the neutrophil/lymphocyte ratio and d-dimer levels as a severity factor in patients with covid-19 treated in an emergency room at the Guillermo Almenara Irigoyen National Hospital, Lima-Peru, April 2021.
(Universidad Privada Norbert Wiener, 2022-06-04) Portillo Muñoz, Juanita; Champa Guevara, Cesar Alfonso
COVID-19 is an infectious disease caused by an RNA beta coronavirus called SARS-CoV-2, which affects the respiratory tract and other organs by binding to ACE-2 receptors. In March 2020, the WHO declared it a pandemic due to its rapid spread and the unprecedented global health crisis it caused. The objective of this research project is to evaluate the role, clinical utility, and relationship of two commonly used biomarkers in clinical laboratories—the neutrophil/lymphocyte index and D-dimer levels—as early predictors of COVID-19 severity. This will help stratify patients based on severity, providing healthcare providers with a useful tool for more timely diagnosis and treatment. The study will use a hypothetical-inductive approach, with a quantitative, applied, correlational, cross-sectional, and retrospective design. The sample will consist of patients admitted to the COVID emergency area at the Guillermo Almenara Irigoyen National Hospital, who meet the inclusion and exclusion criteria. Data will be collected from electronic medical records and processed using SPSS to analyze the correlation between the two variables.
Acceso abierto
Usefulness of neutrophil/lymphocyte ratio in adult COVID-19 patients conducted at Unilabs laboratories, Callao, 2021
(Universidad Privada Norbert Wiener, 2023-11-05) Meza Zavala, Roberto Antonio; Rosales Asto, Karen Ruth; Champa Guevara, Cesar Alfonso
The neutrophil/lymphocyte ratio is a fraction of the absolute neutrophil count divided by the absolute lymphocyte count, which can predict COVID-19 prognosis. This study aimed to determine the utility of the neutrophil/lymphocyte ratio in adult COVID-19 patients at Unilabs, Callao, in 2021. The methodology was quantitative, descriptive, cross-sectional, and based on a sample of 100 patient records. A checklist with a reliability of 0.95 was used. Results showed that 30% of the sample were aged between 60 and 69 years, 70% were male, and 89% had a high-risk score. Conclusion: The neutrophil/lymphocyte ratio was useful for assessing the risk of adult COVID-19 patients, with a high-risk outcome.