Examinando por Materia "Neoplasias Colorrectales"

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Benefits of probiotics in colorectal cancer
(Universidad Privada Norbert Wiener, 2020-12-16) Cotrina Barrios, Leidy Brighity; Dávila Córdova, Jennifer Estefania
The present secondary research entitled as a critical review: “Benefits of probiotics in colorectal cancer”, aimed to identify the benefits of probiotics in patients with colorectal cancer. The clinical question was: Will probiotics produce benefits in adults over 50 years of age who suffer from colorectal cancer? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PubMed, Scielo, HINARI and LILACS, finding 31 articles, 5 being selected that have been evaluated by the CASPE critical reading tool, finally selecting the Prospective Controlled Clinical Trial titled “Usage of Probiotics and its Clinical Significance at Surgically Treated Patients Suffering from Colorectal carcinoma” which has a level of evidence I and Grade of Recommendation I, according to the expertise of the researcher. The critical comment allowed us to conclude that there are great benefits of probiotics, since by regulating the intestinal microbiota, they have a positive impact on the health of the patient with colorectal cancer, both at the digestive and extra-digestive levels.
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Critical review: Benefits of dairy consumption in reducing colorectal cancer risk.
(Universidad Privada Norbert Wiener, 2022-07-26) Espinoza Cárdenas, Mercedes; Bohórquez Medina, Sofia Lorena
The research is titled: “Benefits of dairy consumption in reducing the risk of colorectal cancer”, and its objective was to identify the benefits of dairy consumption in reducing the risk of colorectal cancer. The objective of the research was to answer the following question: Does the consumption of dairy products reduce the risk of colorectal cancer in adults over 18 years of age? It was carried out under the NuBE methodology. The search for articles was carried out in the scientific bases: Science Direct, Pubmed/MEDLINE, Scielo, Scopus and WOS, finding 27 articles, of which 10 were selected, whose quality evaluation was carried out using the CASPE tool, at the end of the process evaluation, the systematic review was selected: “Dairy Consumption and Risk of Conventional and Serrated Precursors of Colorectal Cancer: A Systematic Review and Meta-Analysis of Observational Studies” whose level of evidence It is “AII” and with a “STRONG” degree of recommendation. Likewise, the critical comment made it possible to conclude that there are important benefits of consuming dairy products (especially yogurt and cheese) in colorectal cancer, because they provide nutrients such as calcium and probiotics that are key to the health of patients with colorectal cancer.
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Critical review: consumption of a high-fat diet as a dietary risk factor for colorectal cancer.
(Universidad Privada Norbert Wiener, 2018-12-07) Lamas Espinoza, Samantha Seribeth; Bohórquez Medina, Andrea Lisbet
Among the 36 types of cancer, colorectal cancer (CRC) is the third leading cause of cancer and the second leading cause of cancer-related deaths. It should be noted that it is a type of cancer that is associated with obesity and eating patterns, and that could be related to a high consumption of fat in the diet. For this, the principles of evidence-based nutrition were used as a methodology. Likewise, a systematic search was carried out in 5 databases, Scopus, WOS, Pubmed, Embase and Science Direct, from the last 5 years, which allow us to answer the research question related to the consumption of high-fat diets, and the risk of colorectal cancer in adults. After the selection of articles, they were evaluated through a critical reading tool to determine the degree of recommendation and level of evidence. It was found that less adherence to a healthy diet such as the Mediterranean diet, or a reduction in foods rich in fiber, as well as a low consumption of dairy products or dietary calcium, is associated with an increased risk of colorectal cancer, as is excess of alcohol and red meat.
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Critical review: effect of consuming whole grains on the prevention of colorectal cancer
(Universidad Privada Norbert Wiener, 2019-12-09) Valle Elescano, Renee Amparo; Bohórquez Medina, Andrea Lisbet
Colon cancer is in first place in the case of cancer morbidities. It is estimated that each year one million new diagnoses and half a million deaths are identified. It should be noted that it is a type of cancer that is associated with obesity and dietary patterns, including low consumption of dietary fiber. The objective of the present review was to know the effect of consuming whole grains on the prevention of colorectal cancer. The principles of evidence-based nutrition were used as a methodology. A systematic search was carried out in 5 databases, Scopus, WOS, Pubmed, Embase and Science Direct, from the last 5 years, to answer the research question related to the consumption of whole grains and the risk of colorectal cancer in adults. After the selection of articles, they were evaluated through a critical reading tool to determine the degree of recommendation and level of evidence. It was found that the consumption of whole grains is associated with a reduction in the risk of colorectal cancer in different percentages, depending on the intake, which is detailed in the critical comment.
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Critical review: effect of omega-3 fatty acid supplementation on nutritional indicators and clinical outcomes in patients with colorectal cancer.
(Universidad Privada Norbert Wiener, 2021-07-22) Windmueller Cortés, Andrea Marina; Palma Gutiérrez, Edgardo Jhoffire
The Evidence-Based Nutrition (NuBE) methodology was used to develop this work. The information search was carried out in Medline and Cochrane, finding 62 articles, 6 being selected that have been evaluated by the CASPE critical reading tool. The critical commentary allowed us to conclude that supplementation with 3 g of omega-3 fatty acids of marine origin did not improve nutritional indicators and clinical outcomes in this group of adult patients with colorectal cancer.
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Critical review: effectiveness of perioperative oral immunonutrition to avoid postoperative complications to colorectal cancer surgery patients
(Universidad Privada Norbert Wiener, 2024-06-12) Colan Ortiz, Gerson Ricardo; Bohórquez Medina, Andrea Lisbet
The academic work was based on evidence regarding perioperative immunonutrition to prevent postoperative complications in patients who underwent colorectal cancer surgery. It was found that no single immunonutrient can prevent all postoperative complications; however, glutamine is the most effective in reducing TNF-α levels and shortening hospital stays. Similarly, the combination of omega-3 and arginine was the most optimal for lowering IL-6 levels. Lastly, probiotics were the most effective in reducing pneumonia incidence in colorectal cancer patients.
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Critical Review: Influence of intestinal microbiota alteration on the development of colorectal cancer.
(Universidad Privada Norbert Wiener, 2020-12-10) Oscco Huayta, Villiam Anibal; Bohórquez Medina, Andrea Lisbet
According to the World Health Organization (WHO), cancer is a public health problem. Among them, colorectal cancer has the highest incidence. The present investigation, Influence of the alteration of the intestinal microbiota on the development of colorectal cancer, was developed as a critical review. Objective: Evaluate the scientific literature through a critical reading of it, using the Critical Appraisal Skills Program Spanish (CASPE) tool in published studies. The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in PUBMED, SCIELO, SCOPUS, SCIENCE DIRECT, REDALYC, DIALNET, LILACS, finding 87 articles, selecting 29 that were evaluated by the CASPE critical reading tool, selecting the Systematic Review entitled Preclinical and clinical relevance of probiotics and synbiotics in colorectal carcinogenesis: a systematic review, which has a level of evidence AI and Grade of Recommendation Strong, according to the researcher's expertise. The critical commentary concludes that intestinal dysbiosis influences colorectal carcinogenesis. However, more studies are necessary to identify the characteristics of the eubiosis profile. It is important that new prophylactic, diagnostic and therapeutic strategies be carried out based on research into the intestinal microbiota.
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Critical Review: Mediterranean diet in the reduction of colorectal cancer
(Universidad Privada Norbert Wiener, 2020-12-22) Jahuira Huarcaya, Genoveva Lidia; Bohórquez Medina, Andrea Lisbet
Globally, colorectal cancer (CRC) occupies fourth place and reaches an incidence of more than 20% in men and around 16% in women. On the other hand, adherence to a Mediterranean diet is associated with a reduced risk of metabolic diseases and cancer. Therefore, the objective of this review was to determine whether the consumption of a Mediterranean diet can reduce the risk of colorectal cancer. For the development of this review, the principles of evidence-based nutrition were used as a methodology. For this reason, a systematic search was carried out in 5 databases, Scopus, WOS, Pubmed, Embase and Science Direct, from the last 5 years, which allow us to answer the research question related to the consumption of the Mediterranean diet and the risk of cancer. colorectal in adults. After the selection of articles, they were evaluated through a critical reading tool to determine the degree of recommendation and level of evidence. Finally, the article with the highest degree of evidence is developed in the critical commentary, in order to extract recommendations for the professional practice of nutritionists and other health professionals. It was found that greater adherence to a Mediterranean diet is associated with a reduction in the incidence of colorectal cancer, which is detailed in the critical commentary.
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Critical review: relationship between serum vitamin D levels and survival of patients with colorectal cancer
(Universidad Privada Norbert Wiener, 2022-10-18) Gonzalez Huamani, Jose Smith; Palma Gutiérrez, Edgardo Jhoffire
An information search was carried out in the Medline and Cochrane databases, finding 60 articles, 6 being selected, which have been evaluated by the CASPE critical reading tool, finally the selected article allowed us to conclude that there is a significant association between the highest concentrations. high levels of vitamin D in the blood and better survival in patients with colorectal cancer.
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Critical review: relationship of fusobacterium nucleatum in the development of colorectal cancer.
(Universidad Privada Norbert Wiener, 2021-06-04) Meléndez Barzola, Carlos Enrique; Bohórquez Medina, Andrea Lisbet
The World Health Organization (WHO) reports that colorectal cancer is the third leading cause of death worldwide, making it a public health issue due to its high incidence. This research, titled "Influence of intestinal dysbiosis on the development of colorectal cancer," was developed as a critical review. The objective was to evaluate the available scientific research through a critical reading using the Critical Appraisal Skills Programme (CASPE) tool on studies published about the influence of intestinal microbiome alterations (intestinal dysbiosis) in the development of colorectal cancer. The clinical question was: Does intestinal dysbiosis influence the development of colorectal cancer? The methodology used was Evidence-Based Nutrition (NuBE). The search for information was conducted in WEB OF SCIENCE, SCOPUS, EMBASE, PUBMED, SCIELO, DOAJ, SCIENCE DIRECT, ERIHPLUS, HINARIN, finding 114 articles, with 17 selected and evaluated using the CASPE tool. The systematic review titled "Fusobacterium nucleatum in the colorectum, and its association with cancer risk and survival: a systematic review and meta-analysis" was selected, with evidence level II and a strong recommendation grade, according to the researcher’s opinion. The critical commentary concludes that intestinal dysbiosis, especially the increase of Fusobacterium nucleatum, plays an important role in the development and prognosis of colorectal cancer. However, more clinical trials in humans are needed to establish Fusobacterium nucleatum as a causal factor or biomarker for development, which could generate low-cost diagnostic tools, as well as prophylactic and/or therapeutic measures.
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Critical review: vitamin D supplementation on plasma calcidiol levels and survival in colorectal cancer patients.
(Universidad Privada Norbert Wiener, 2022-09-06) Puente Villena, Diego Alberto; Bohórquez Medina, Andrea Lisbet
Secondary research titled: Critical review: “Vitamin D supplementation on plasma calcidiol levels and survival in patients with colorectal cancer.” We aimed to identify the effect that vitamin D supplementation has on plasma calcidiol levels and survival in patients with colorectal cancer. The clinical question was: Does vitamin D supplementation increase plasma vitamin D levels and improve survival rate in patients with colorectal cancer? The Evidence-Based Nutrition methodology was used. The information search was carried out in Science Direct, Pubmed, Splingerlink, Lilacs, Latindex and Scielo, finding 60 articles, 15 being selected that have undergone exhaustive selection with the CASPE tool such as “the effect of vitamin D supplementation on survival in patients with “colorectal cancer: systematic review and meta-analysis of randomized controlled trials.” which met the expectations of the objectives proposed herein, and also obtained a STRONG recommendation grade and A1 level of evidence. Vitamin D supplementation at doses of 2000 IU to 4000 IU showed improvements in plasma calcidiol levels and overall survival and relapse-free survival rates in patients with colorectal cancer.
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Effect of oral vitamin d supplementation on survival of adult colorectal cancer patients.
(Universidad Privada Norbert Wiener, 2020-12-11) Julca Rupay, Marlene Rosario; Palma Gutiérrez, Edgardo Jhoffire
This critical review aimed to analyze the effect of oral vitamin D supplementation and its role in the survival of adult patients with colorectal cancer. The clinical question was: Does oral vitamin D supplementation increase survival time in adult patients with colorectal cancer? The Evidence-Based Nutrition (NuBE) methodology was used. Information was searched in Medline, Wiley Online Library, HINARI, Scielo, and Redalyc, finding 225 articles, of which 6 were selected and evaluated using the CASPE critical reading tool. The randomized clinical trial titled 'Effect of high-dose vs. standard-dose vitamin D3 supplementation on progression-free survival in patients with advanced or metastatic colorectal cancer: The SUNSHINE randomized clinical trial' was chosen, possessing a level of evidence I and a strong recommendation grade. The critical commentary concluded that high-dose vitamin D improved survival in colorectal cancer patients compared to those who consumed the standard dose. Further studies are needed to extrapolate these results to the general population.
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Effectiveness of colorectal cancer screening in reducing mortality in adults
(Universidad Privada Norbert Wiener, 2018-07-08) Huacho Susanivar, Cerao Rosario; Maylle Durand, Katherine; Gamarra Bustillos, Carlos
Objective: To systematize the evidence on the effectiveness of colorectal cancer screening in reducing mortality in asymptomatic individuals. Methodology: This was a systematic, observational, and retrospective review. The search was limited to full-text articles, subjected to critical reading, using the Grade assessment to identify their level of evidence. Of the total 100% (10) scientific articles reviewed, 40% (4) were from Spain, 10% (1) from the United Kingdom, 10% (1) from China, 10% (1) from Canada, 10% (1) from Norway, 10% (1) from the United States, and 10% (1) from the Netherlands. Results: According to the findings of the reviewed scientific studies, 9 out of 10 articles demonstrated that colorectal cancer screening is effective in reducing mortality in asymptomatic individuals. Conclusions: The systematic review allows us to evidence that colorectal cancer screening is effective in reducing mortality in asymptomatic individuals because it is a test that provides greater accuracy in the early diagnosis of colorectal cancer in its initial stages, thereby contributing to prevention, timely treatment, and increasing the chances of a cure.
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Effectiveness of fiber intake to prevent colorectal cancer in adults
(Universidad Privada Norbert Wiener, 2019-08-18) Silva Villajulca, Frida Liz; Alfaro Almonte, Edith Veronica; Gonzales Saldaña, Susan Haydee
Objective: Systematize the evidence about the effectiveness of fiber intake to prevent colorectal cancer in adults. Materials and Methods: It is a Systematic Review that structures the products of various investigations, recognizing the most salient to answer specific questions of daily work. The follow-up was directed to articles with full text submitted to a critical reading, the recommendation will be made using the GRADE system. Results: According to the results obtained from the systematic review carried out on ten scientific articles in the present study, these come from China (40%), followed by the United Kingdom (30%), Italy (10%), Malaysia (10%), Sweden (10%). of the articles are systematic reviews, followed by 40% (4) meta-analysis, randomized clinical trial 10% (1), cohort 10% (1) cases and controls 10% (1). Of the total of 10 articles reviewed, 100% (n=10) recommended fiber intake to prevent colorectal cancer in adults. Conclusions: of the total of 10 articles reviewed, 100% evidence the effectiveness of fiber intake to prevent colorectal cancer in adults.
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Effectiveness of laparoscopic colectomy versus conventional colectomy in reducing hospital stay and complications in postoperative colon cancer patients
(Universidad Privada Norbert Wiener, 2018-12-12) Suclupe Huertas, Iris Mirian; Raymundo Ramos, Chaveli Iluminada; Pretell Aguilar, Rosa María
The summary of the present research work on laparoscopic colectomy versus conventional colostomy in reducing hospital stay and complications in post-operative patients with colon cancer is quantitative and has a meta-analysis study design, randomized controlled trial and cohort, using the grade evaluation system for identifying the level of evidence, found in the following databases: Cochrane Library, British Medical Journal, Pubmed, Wiley Online Library. Of the 10 articles systematically reviewed, 30% are meta-analyses, 50% are randomized controlled trials and 20% are cohort studies. These studies come from the countries of China (40%), followed by Japan (20%), Italy (10%), North Korea (10%), England (10%) and Belgium (10%). 90% point out that laparoscopic colectomy is more effective than conventional colectomy in reducing hospital stay and complications in post-operative patients with colon cancer, and on the other hand, 10% point out that there is no difference. The present study demonstrates that laparoscopic colectomy is more effective than conventional colectomy in terms of hospital stay, patients have less postoperative bleeding, and their risk of infection is lower.
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Influence of flavonoid intake on the risk of developing colorectal cancer in adults.
(Universidad Privada Norbert Wiener, 2022-05-30) Hamasaki Matos, Angie Joyce; Bohórquez Medina, Andrea Lisbet
Colorectal cancer is classified as the third most common cancer and the second most deadly in the world and dietary components can be protective factors. Therefore, the present academic work aims to evaluate updated evidence through a critical clinical commentary on the influence of flavonoid consumption in reducing the risk of developing colorectal cancer in adults. To do so, the five stages of NuBE were used and, through the CASPe tool, the scientific articles were classified according to their degree of evidence. From the review and evaluation process, the article Dietary Flavonoids and the Risk of Colorectal Cancer: An Updated Meta-Analysis of Epidemiological Studies was selected. The study structures, describes and analyzes the data in a manner relevant to the type of study that the authors carry out. The statistical analysis is presented in a concise and precise manner, which would allow the study to be replicated. The discussion raised by the authors highlights the main findings and puts them into context by comparing them with similar works previously published. Finally, it can be concluded that it is necessary to generate more high-level scientific evidence that allows extrapolation of results to the general population.
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Nutritional intervention with probiotics in the postoperative state in patients with colorectal cancer
(Universidad Privada Norbert Wiener, 2023-01-26) Rojas Galarza, Evelyn Fiorela; Bohórquez Medina, Andrea Lisbet
This research titled as a critical review: nutritional intervention with probiotics in the postoperative state in patients with colorectal cancer aimed to establish the administration of probiotics. The clinical question was: Does nutritional intervention (prevent constipation or diarrhea) for the progress of intestinal flora , have a better standard of living) with probiotics (Lactobacillus acidophilus, Bifidobacteria, Saccharomyces boulardii) in adult patients after CRC surgery? The Evidence-Based Nutrition methodology was used, finding 31 articles, 18 being chosen that have been evaluated by the CASPE critical reading instrument, finally choosing the systematic study titled The effects of probiotics on reducing the colorectal cancer surgery complications: A periodic review during 2007–2017, which has a level of evidence AII and a strong Grade of Recommendation, according to the researcher's experience. The critical observation allowed us to conclude that the administration of probiotics in post-operative colorectal cancer patients has great relevance in reducing inflammation.
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Protective effect of calcium present in dairy products in reducing the risk of colorectal cancer
(Universidad Privada Norbert Wiener, 2024-07-27) Condo Leonardo, Diana Alejandrina; Bohórquez Medina, Andrea Lisbet
Colorectal cancer originates in the colon or rectum, typically beginning with the rapid growth of altered morphology cells that divide, grow, and spread, affecting various tissue parts, starting with a polyp that can evolve into carcinoma or CCR. In this regard, improving dietary and environmental factors will not only reduce the future risk of cancer. This secondary research, titled 'Critical Review: Protective Effect of Calcium in Dairy Products on the Reduction of Colorectal Cancer Risk', aimed to highlight the benefits of consuming dairy products and derivatives in reducing colorectal cancer mortality rates and improving quality of life. The critical review concluded that various studies support the idea that the intake of total dairy products and derivatives reduces the risk of colorectal cancer, with mechanisms such as calcium and other nutrients in dairy products playing a protective role.
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Whole grain intake and colorectal cancer survival
(Universidad Privada Norbert Wiener, 2022-04-28) Puma Castañeda, Medy Yohana; Bohórquez Medina, Andrea Lisbet
This critical review is a secondary research entitled: "Whole grain consumption and colorectal cancer survival", which aims to discover the benefits of whole grain consumption for the survival of patients diagnosed with colorectal cancer from the first stage. The clinical question was: What is the effect of whole grain consumption on the survival of adult patients suffering from colorectal cancer from the first stage? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in different databases such as Scopus, WOS, Science Direct, Pubmed, LILACS, Google scholar and Embase; Finding 165 articles, selecting 21 that have been evaluated by the critical reading tool CASPE, selecting the systematic review entitled "The Impact of Whole Grain Intake on Gastrointestinal Tumors: A Focus on Colorectal, Gastric, and Esophageal Cancers", which has a level of evidence AI and strong Grade of Recommendation, according to the researcher's experience. The critical commentary allowed to conclude that the consumption of whole grains favors to decrease the risk of colorectal cancer and improves the survival of patients with colorectal cancer, although in this last point it is suggested to carry out more research.