Examinando por Materia "Neuroprotection"

Mostrando 1 - 8 de 8

Acceso abierto
Effectiveness of assisted ventilation for neuroprotection in newborns with hypoxic encephalopathy
(Universidad Privada Norbert Wiener, 2018-07-08) Aquino Quintana, Judith Angélica; Gonzales Napuri, Flor De Maria; Remuzgo Artezano, Anika
Objective: To analyze and systematize the evidence on the efficacy of assisted ventilation for neuroprotection in newborns with hypoxic encephalopathy. Materials and Methods: The type of research was qualitative, and the design was systematic review, in which the unit of analysis is the primary original studies, with a population of 25 articles and a sample of 10 articles. The instrument used was from the Scielo, Medline, and Pubmed databases, with articles published in Spanish and English and not older than ten years. The GRADE system was used to evaluate the quality of evidence and the strength of recommendations. Results: Of the 10 articles, 100% were qualitative studies, with 80% from Cuba and 20% from Mexico. Regarding design, 40% were descriptive, retrospective, and observational, 30% were prospective and longitudinal, 20% were correlational, and 10% were explanatory. Conclusions: These 10 scientific articles conclude that 80% found mechanical ventilation to be effective as a neuroprotective measure for newborns, helping to provide oxygen in a timely manner, thus preventing physiological and biochemical changes that could affect the newborn’s central nervous system. The remaining 20% concluded that it was not effective and that there was some degree of neurological sequelae.
Acceso abierto
Effectiveness of assisted ventilation for neuroprotection in newborns with hypoxic encephalopathy
(Universidad Privada Norbert Wiener, 2018-07-08) Aquino Quintana, Judith Angélica; Gonzales Napuri, Flor De Maria; Remuzgo Artezano, Anika
Objective: To analyze and systematize the evidence on the efficacy of assisted ventilation for neuroprotection in newborns with hypoxic encephalopathy. Materials and Methods: The type of research was qualitative, and the design was systematic review, in which the unit of analysis is the primary original studies, with a population of 25 articles and a sample of 10 articles. The instrument used was from the Scielo, Medline, and Pubmed databases, with articles published in Spanish and English and not older than ten years. The GRADE system was used to evaluate the quality of evidence and the strength of recommendations. Results: Of the 10 articles, 100% were qualitative studies, with 80% from Cuba and 20% from Mexico. Regarding design, 40% were descriptive, retrospective, and observational, 30% were prospective and longitudinal, 20% were correlational, and 10% were explanatory. Conclusions: These 10 scientific articles conclude that 80% found mechanical ventilation to be effective as a neuroprotective measure for newborns, helping to provide oxygen in a timely manner, thus preventing physiological and biochemical changes that could affect the newborn’s central nervous system. The remaining 20% concluded that it was not effective and that there was some degree of neurological sequelae.
Acceso abierto
Effectiveness of induced hypothermia in neuroprotection of the newborn with hypoxic-ischemic encephalopathy.
(Universidad Privada Norbert Wiener, 2018-03-25) Félix Román, Sarita Leonor; Rosado Burgos, Benjamin Jean Franco; Rivera Lozada de Bonilla, Oriana
Objective: To systematize and evidence the efficacy of kidney transplantation in the reduction of the risk of graft loss for survival in pediatric patients. Materials and Methods: The study is quantitative, with a systematic review design. The population consisted of 39 articles that were reviewed, and 10 scientific articles were selected as the sample. Of these, 20% (n=2/10) were systematic reviews, 10% (n=1/10) were systematic review and meta-analysis, and 70% (n=7/10) were cohort studies. According to the quality of evidence, 30% was rated as high and 70% as moderate. In terms of the strength of recommendations, 30% were strong and 70% were weak, based on the country where the research was conducted. Results: The reviewed articles show that 40% (n=4/10) indicate the efficacy of renal replacement therapy in the risk of graft loss for survival in pediatric patients. Another 40% (n=4/10) state that it is partially effective, and 20% (n=2/10) state it is not effective. Conclusion: It is concluded that 40% (n=4/10) indicates that renal replacement therapy is partially effective in the risk of graft loss for survival in pediatric patients.
Acceso abierto
Effectiveness of induced hypothermia in neuroprotection of the newborn with hypoxic-ischemic encephalopathy.
(Universidad Privada Norbert Wiener, 2018-03-25) Rosado Burgos, Benjamin Jean Franco; Rivera Lozada de Bonilla, Oriana
Method: The study approach was quantitative, correlational, and the population consisted of 145 patients from the National Strategy for Tuberculosis Prevention and Control. The technique used was the interview, and the instruments used were questionnaires, the RFT 5-33 created by Pilar Amaya, and the Morisky adherence questionnaire. Results: The most prominent sociodemographic characteristics in terms of age were 35.9% between 15 to 33 years, 35.2% between 34 to 51 years; in terms of sex, 50.3% were female and 49.7% male. Regarding educational level, 75.2% had completed secondary education, 10.3% had incomplete secondary education, and 49.7% were from a nuclear family. In terms of family type, 56.6% belonged to a nuclear family, 39.3% to an extended family, 2.8% to a modified nuclear family, and 0.7% had partners. Regarding family risk, 85% were in threatened families, 14% in high-risk families, and 1% in low-risk families. Regarding pharmacological adherence, 86% were non-adherent and 14% were adherent. Conclusion: No relationship was found between total family risk and adherence to pharmacological therapy in individuals affected by tuberculosis at the "Huáscar XV" health center – 2018 (Chi-squared p value: = 0.597).
Acceso abierto
Effectiveness of induced therapeutic hypothermia for neuroprotection in newborns with hypoxic-ischemic encephalopathy
(Universidad Privada Norbert Wiener, 2018-12-16) Asencios Nieto, Yeny Elizabeth; Cabrera Andía, Macedonia; Uturunco Vera, Milagros Lizbeth
MATERIAL AND METHOD: The systematic review of the 10 articles on the effectiveness of induced therapeutic hypothermia for neuroprotection in newborns with hypoxic ischemic encephalopathy were found in the following databases: Cochrane, Scielo and Pubmed. Of the 10 articles reviewed, 60% (6/10) correspond to the methodological design of systematic reviews and/or meta-analysis, 30% (3/10) are randomized clinical trials and 10% (1/10) are studies cross. All of them were analyzed according to the Grade scale to determine their strength and quality of evidence. RESULTS: 100% of the reviewed articles are conclusive, these are supported by 6 systematic reviews, 3 randomized clinical trials and 1 cross-sectional study, all of which suggest the use of induced therapeutic hypothermia is the best alternative for the hospital management of newborns. with hypoxic ischemic encephalopathy. However, some of these authors suggest conducting further follow-up studies to verify the effectiveness of this intervention in the long term. CONCLUSIONS: Of the 10 articles reviewed, 100% (10/10) show the effectiveness of induced therapeutic hypothermia in neuroprotection in newborns with hypoxic ischemic encephalopathy, because it reduces neurological damage, sequelae and a decrease in the mortality rate. .
Acceso abierto
Effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients
(Universidad Privada Norbert Wiener, 2017-12-03) Félix Saavedra, Flor de María; Flores Chipana, Ciprian; Pretell Aguilar, Rosa Maria
Objective: To systematize the evidence on the effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients. Methodology: An observational and retrospective systematic review, where the search was restricted to full-text articles, and the selected articles underwent critical reading using the GRADE evaluation system to determine their level of evidence. In the final selection, 10 articles were chosen, of which 60% were meta-analyses and 20% were systematic reviews with high evidence quality and strong recommendation strength. Of these, 30% (3) were from China, 10% (1) from Austria, 10% (1) from the United States, and 10% (1) from India. Regarding systematic reviews, 10% (1) were from the USA and 10% (1) from China. With 20% being clinical trials and cohort studies with moderate evidence quality and weak recommendation strength, 10% (1) were from Portugal and 10% (1) from the United States. Results: Among the reviewed evidence, 70% affirm that therapeutic hypothermia contributes to neuroprotection in post-cardiac arrest patients, while 30% suggest that therapeutic hypothermia does not provide any benefit in neurocritical post-cardiac arrest patients. Conclusions: The best-reviewed evidence demonstrates that therapeutic hypothermia reduces neurological damage after cardiac arrest in neurocritical patients.
Acceso abierto
Effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients
(Universidad Privada Norbert Wiener, 2017-12-03) Félix Saavedra, Flor de María; Flores Chipana, Ciprian; Pretell Aguilar, Rosa Maria
Objective: To systematize the evidence on the effectiveness of therapeutic hypothermia compared to normothermia for neuroprotection in post-cardiac arrest patients. Methodology: An observational and retrospective systematic review, where the search was restricted to full-text articles, and the selected articles underwent critical reading using the GRADE evaluation system to determine their level of evidence. In the final selection, 10 articles were chosen, of which 60% were meta-analyses and 20% were systematic reviews with high evidence quality and strong recommendation strength. Of these, 30% (3) were from China, 10% (1) from Austria, 10% (1) from the United States, and 10% (1) from India. Regarding systematic reviews, 10% (1) were from the USA and 10% (1) from China. With 20% being clinical trials and cohort studies with moderate evidence quality and weak recommendation strength, 10% (1) were from Portugal and 10% (1) from the United States. Results: Among the reviewed evidence, 70% affirm that therapeutic hypothermia contributes to neuroprotection in post-cardiac arrest patients, while 30% suggest that therapeutic hypothermia does not provide any benefit in neurocritical post-cardiac arrest patients. Conclusions: The best-reviewed evidence demonstrates that therapeutic hypothermia reduces neurological damage after cardiac arrest in neurocritical patients.
Acceso abierto
Neuroprotective efficacy of therapeutic hypothermia in patients post-cardiac arrest
(Universidad Privada Norbert Wiener, 2018-07-08) Celis Garcia, Erika Mabel; Calsin Pacompia, Wilmer
Systematic observational, retrospective and quantitative review, where the GRADE evaluation system was used to identify the degree of evidence and the strength of recommendation of each article found in the following databases: Scielo, Pubmed, Elvesier, Medline, BVS. 60% (n=6/10) are systematic reviews, 10% (n= 1/10) experimental studies, 20% (n= 2/10) case control, 10% (n= 1/10) cohort study . Likewise, 70% (n=7/10) are of high quality with a strong strength of evidence and 30% (n=3/10) are of moderate quality with a weak strength of evidence. Originating 40% in the USA, 20% in Spain, 10% in Austria, 10% in Canada, 10% in the Czech Republic, and 10% in Germany. Results: all the articles systematically reviewed (n=10/10) indicate a neuroprotective effectiveness of therapeutic hypothermia in post-cardiorespiratory arrest patients. Conclusions: 7/10 of the articles show an improvement in the neurological probabilities of the patients, another 7/10 a better survival to hospital discharge and 4/10 show that there is a decrease in mortality and an improvement in the morbidity of the patient. patient.