Examinando por Materia "Química Farmacéutica"

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Acceso abierto
Capacidades y habilidades del químico farmacéutico hospitalario en egresados de farmacia y bioquímica – Universidad Interamericana para el Desarrollo, Lima 2025
(Universidad Privada Norbert Wiener, 2026-03-25) Rojas Morales, Mirella Victoria; Sotelo Surichaqui, Thalia Alexandra; Guadalupe Sifuentes de Posadas, Luz Fabiola
La presente investigación tuvo como objetivo determinar la relación entre las capacidades y las habilidades del químico farmacéutico hospitalario en egresados de la carrera de Farmacia y Bioquímica de la Universidad Interamericana para el Desarrollo – Lima 2025. El estudio se desarrolló bajo un enfoque cuantitativo, con diseño no experimental, de corte transversal y nivel correlacional. La población estuvo conformada por 180 egresados, de los cuales se seleccionó una muestra de 123 mediante muestreo probabilístico aleatorio simple. Para la recolección de datos se utilizó un cuestionario estructurado con escala tipo Likert, validado por juicio de expertos y evaluado mediante el coeficiente alfa de Cronbach para determinar su confiabilidad. Los resultados evidenciaron una relación significativa entre las capacidades y habilidades del químico farmacéutico hospitalario, obteniéndose un coeficiente de correlación de Spearman de ρ = 0,538 con un valor de p = 0,000. Asimismo, se observó que las diferentes dimensiones evaluadas presentan relaciones positivas, destacando las habilidades de comunicación e interacción como la dimensión con mayor correlación. Se concluye que existe una relación significativa entre las capacidades y las habilidades del químico farmacéutico hospitalario en egresados, lo que evidencia que la formación académica influye en el desarrollo de competencias necesarias para el desempeño profesional en el ámbito hospitalario.
Acceso abierto
Determinación de la calidad de la materia prima celecoxib en seis lotes diferentes mediante los resultados de ensayos fisicoquímicos según USP 39, Lima 2016–2017
(Universidad Privada Norbert Wiener, 2017-11-25) Felipe Chávez, Ross Bereniz; Lázaro Cartolín, Johana Milagros; Guevara Ortega, Freddy Alberto
The present research work was conducted with the objective of determining the quality of celecoxib raw material in six different batches through the results of physicochemical tests according to USP 39. The study population consisted of six batches of raw material analyzed in the quality control area of a national pharmaceutical laboratory, during the period from May 2016 to February 2017. The research methodology was carried out in accordance with the specifications of the USP 39 technical standard. The results were: 100% compliant in description, 100% compliant in identification, 100% compliant in solubility, 100% compliant with less than 0.1% in water determination, 100% compliant with less than 0.2% in residue on ignition, 100% compliant with no more than 20 ppm of heavy metals, 100% compliant with no more than 0.5% in organic impurities, and 100% compliant in assay within a range of 98.0% – 102.0%. These results indicated that the celecoxib raw material from different batches, received by a national pharmaceutical laboratory during the period from May 2016 to February 2017, meets the quality standards established by USP 39, regardless of its place of origin.
Acceso abierto
Equivalencia farmacéutica de medicamentos multifuentes de carbamazepina disponibles en Cercado de Lima marzo–abril 2018
(Universidad Privada Norbert Wiener, 2020-12-03) Barrientos Ríos, Erasmo; Gutierrez De Los Santos, Isaac; Cárdenas Orihuela, Robert Armando
The objective of this research was to determine the pharmaceutical equivalence of three multi-source carbamazepine 200 mg tablets versus the reference drug Tegretol 200 mg tablets (Novartis, Switzerland). Methodology: The multi-source and reference medications were acquired from pharmacies in Lima. Disintegration, friability, hardness, weight, and content assay tests were performed using High-Performance Liquid Chromatography (HPLC). The results were analyzed to establish statistically significant differences. Results: The comparative analysis of the products showed the following: the multi-source medications had an average weight of ($\mathbf{0.32 \pm 7.5 \%}$g). In the hardness test, they reported an acceptable value between ($\mathbf{2 – 2.5 \text{ kg/F}}$). Disintegration showed a time of less than 30 minutes. Friability was less than 1.5%. The active principle assay by HPLC ranged between 92.0% and 108.0%. It is noteworthy that all products comply with the official specifications for identification and assay of the active ingredient, hardness, and disintegration time. Conclusion: The multi-source carbamazepine 200 mg tablets evaluated and sold in Cercado de Lima are pharmaceutically equivalent when compared to the innovator drug (Tegretol).
Acceso abierto
Factores condicionantes y buenas prácticas de dispensación en los químicos farmacéuticos que laboran en los establecimientos farmacéuticos del distrito de los olivos, julio- diciembre, Lima - Perú, 2024
(Universidad Privada Norbert Wiener, 2025-04-07) Lazo Rojas, Ayde; Rojas Ticona, Yony Jaime; Bustamante Fustamante, Flor Lidia
This research aimed to determine the conditioning factors that affect Good Dispensing Practices among Pharmacists working in pharmaceutical establishments in the Los Olivos district, July-December, Lima, Peru, 2024. Methodology: Deductive, quantitative, basic, non experimental, correlational, and cross-sectional research. The sample consisted of 190 pharmaceutical establishments (190 pharmacists), and was conducted through a survey. Results: Pharmacists working in pharmaceutical establishments had a high percentage of poor working conditions, with 81.1% indicating poor working conditions. 54.7% had average workplace communication, 78.9% had a high percentage of personal problems, 81.6% had a high percentage of human talent management, and 57.4% had a low percentage of infrastructure and equipment, indicating good conditions. Regarding the Good Dispensing Practices variable, the percentage was fair, with a percentage of 49.5%. This demonstrated that dispensing practices are fair. Conclusion: It was determined that there is significant agreement between the conditioning factors and the GDPs, as their indicator of workplace communication. There was no significant correlation for some indicators in the establishments where the Pharmaceutical Chemists work in the Los Olivos district, Lima, Perú.
Acceso abierto
Gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico Pharmed Corporation, 2024
(Universidad Privada Norbert Wiener, 2025-05-28) Cáceres Barzola, Stefany Mayra; Ynfantes Almeyda, Sonia Pilar; Pinedo Panduro, Lauro Sócrates
Se tuvo como objetivo: Determinar la relación entre la gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico Pharmed CORPORATION, 2024. Metodología: Se trabajó con una metodología cuantitativa, de diseño observacional, de corte transversal y nivel correlacional. Población y muestra: Fue integrada por 74 trabajadores en el laboratorio farmacéutico Pharmed CORPORATION de las áreas de Control de calidad, producción y almacén, como técnica de estudio se aplicó la encuesta a través del uso de dos cuestionarios, cabe recalcar que dichos instrumentos son validados y confiables. Resultados: Se observó que al correlacionar la gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico, se encontró que del grupo que presenta una gestión de la cadena de suministro mala, manifiesta una productividad baja en un 14,9% en su mayoría. Los que presentan una gestión de la cadena de suministro regular, manifiestan una productividad media en un 27,0% en su mayoría. Por último, aquellos que presentan una gestión de la cadena de suministro buena, manifiestan una productividad alta en un 21,6% en su mayoría. Se concluyó que hay relación directa entre la gestión de la cadena de suministro y la productividad de los trabajadores en el laboratorio farmacéutico Pharmed CORPORATION, 2024, con una significancia del 0.000 menor al 0.01.
Acceso abierto
Interés y conocimiento sobre el soporte nutricional parenteral del profesional químico farmacéutico del Hospital Regional Lambayeque, 2024
(Universidad Privada Norbert Wiener, 2025-10-02) Oblitas Guerrero, Luz Aurora; Ñañez del Pino, Daniel
The purpose of this study was to determine the relationship between interest and knowledge about parenteral nutritional support among pharmaceutical chemists working at the Regional Hospital of Lambayeque. The study was a basic, quantitative and cross-sectional design, with a sample of 30 pharmaceutical chemists who responded to two questionnaires. Regarding the characteristics of the population, it was found that the majority was made up of women (63.3%). On the other hand, 60% of the respondents presented a regular level of interest. Regarding the motivation dimension, 43.3 % reached a regular level; while, in the attitudes dimension, all participants showed a high level; and in the experiences and links dimension, the regular level predominated, with 80 %. In relation to the knowledge variable, it was predominantly high (56.7%). It was identified that those with high motivation tended to exhibit regular knowledge (26.67%). Similarly, those with high attitudes had a greater presence among those with high knowledge (56.67%). Likewise, in the dimension experiences and links, the regular level predominated (80%), of which 50% had high knowledge. However, no significant difference was found between the variables (rho = -0.245; p = 0.193), nor between the aforementioned dimensions and knowledge. In conclusion, there is no significant relationship between interest and knowledge in the population studied.
Acceso abierto
Perfil del químico farmacéutico especializado en fórmulas magistrales
(Universidad Privada Norbert Wiener, 2017-11-22) Estrada Velasque, Carmelo; Quesada Peralta, José Luis; Jáuregui Maldonado, José Fidel
Observational study design, conducted in 2017 in the city of Lima, in which 100 Pharmaceutical Chemists working in authorized Specialized Pharmaceutical Establishments, both public and/or private, were surveyed as the sample. The functions and activities they perform, those in which they could potentially be involved, and the ideal professional profile of the Pharmaceutical Chemist specialized in the preparation of magistral formulas were evaluated. A research instrument was designed with criteria validated by experts in a questionnaire of questions regarding performance, competencies, and skills of the Pharmaceutical Chemist engaged in the preparation of magistral formulas. After the analysis, evaluation, and processing of the sample, the following results were obtained: Of the 100 Pharmaceutical Chemists consulted (100%), it was found that 65% (65) responded that the activity they considered most important is “Interviewing and selecting personnel for hiring in the field of magistral formulas.” Likewise, 58% (58) of all respondents considered very important the “Resolution of questions and concerns raised by medical personnel, nursing staff, and users of magistral formulas.” In third place, with 56% (56), was “Affinity and vocation for the preparation of magistral compounds,” which may be considered highly significant since 99% of respondents indicated that they considered it at least important (resulting from the combination of those who considered it important and very important). Therefore, it is concluded: the functions and activities performed by the Pharmaceutical Chemist specialized in the preparation of magistral formulas are planning, organization, supervision, preparation, and research of magistral formulas; there are deficiencies in the teaching of courses on processes and preparation of magistral formulas.