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Examinando por Materia "Shock, Septic"

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    Effectiveness of activating a sepsis code to reduce in-hospital mortality in patients with severe sepsis/septic shock
    (Universidad Privada Norbert Wiener, 2020-08-02) Loayza Goicochea, Oscar Roger; Pretell Aguilar, Rosa María
    Objective: Systematize the available evidence on the effectiveness of activating a sepsis code to reduce in-hospital mortality in patients with severe sepsis/septic shock. MATERIALS AND METHODS: The type of research is quantitative, the design is a systematic review of 10 articles that were obtained from the following databases: Pubmed, Biomedcentral, Sciencedirect, Medintensiva, Scielo. Of the 10 articles reviewed and analyzed, 50% (n= 5/10) are Quasi-experimental, 40% (n= 4/10) Cohort and 10% (n=1/10) are systematic reviews. According to the quality of the evidence, it was found to be 90% moderate and 10% high. According to the recommendation strength it is 90% weak and 10% strong. According to the country where the investigations were carried out, they correspond to Spain 70%, the United States 20% and Cuba 10%. Results: According to the review, it is evident that 100% of the articles (n = 10/10) indicate that the implementation of the sepsis code is effective in reducing in-hospital mortality in patients with severe sepsis and septic shock. Conclusion: It is concluded that 10 of 10 evidence reviewed and analyzed demonstrate that the activation of a sepsis code is effective in reducing in-hospital mortality in patients with severe sepsis/septic shock.
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    Effectiveness of noradrenaline versus dopamine in patients with septic shock that come to the emergency service
    (Universidad Privada Norbert Wiener, 2018-11-25) Chavez Davila, Zoila Doris; Villarroel Vega, Lizeth Geraldine; Perez Siguas, Rosa Eva
    Objective: To analyze and systematize the evidence on the efficacy of dopamine versus norepinephrine for patients with septic shock in the emergency department. Materials and methods: This study is a systematic review. The GRADE system was used to assess the quality of the evidence and grade the strength of the recommendations. The search was conducted in the following databases: LILACS, SciELO, Cochrane Plus, PubMed, MEDLINE, Epistemonikos, and EBSCO. Of the 10 articles systematically reviewed, 30% were systematic reviews and meta-analyses, 20% were clinical trials, and 20% were randomized primary studies. Regarding the country of origin, 30% were from the U.S. and China, and 10% were from France, India, England, and Spain. Results: 90% of the articles agree that norepinephrine is more effective than dopamine, as it has a lower incidence of cardiac-related events compared to dopamine, and 10% found no difference in mortality between the two drugs. Conclusions: It is concluded that norepinephrine is more effective than dopamine in patients with septic shock in the emergency department.
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    Efficacy of early goal-directed therapy to reduce mortality in patients with septic shock in critical units
    (Universidad Privada Norbert Wiener, 2019-08-18) Carlos Astudillo, Yossy Isabel; Pacheco Pumarica, Merly Karol; Rivera Lozada de Bonilla, Oriana
    Objective: Systematize evidence on the effectiveness of early goal-directed therapy to reduce mortality in patients with Septic Shock in critical units. Material and methods: Systematic observational and retrospective review, subjected to critical reading and using the GRADE evaluation system to identify the degree of evidence of the articles published in the following databases: PubMed, Sciencedirect, Epistemonikos, Scielo, Researchgate. Of the 10 articles systematically reviewed: 90% (n= 9/10) are meta-analyses, 10% (n= 1/10) are systematic reviews and come from the countries of China (70%), followed by Iran (10 %), the United States (10%) and Korea (10%). Results: 70% (n=7/10) indicate that early goal-directed therapy is effective in reducing mortality in patients with Septic Shock in critical units. 30% (n=3/10) indicate that early goal-directed therapy is not effective in reducing mortality in patients with Septic Shock in critical units. Conclusion: Early goal-directed therapy is effective in reducing mortality in patients with Septic Shock in critical units.
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    Efficacy of noradrenaline compared to dopamine in reducing adverse events in the treatment of patients with septic shock.
    (Universidad Privada Norbert Wiener, 2018-07-08) Patricio Centeno, Luis Alberto; Lugo Ostos, Evila Isabel; Rivera Lozada de Bonilla, Oriana
    The Systematic Review, analysis unit, primary original studies. Databases used: Intramed, Pubmed. Ten articles were selected, of which 80% are systematic reviews and high-quality meta-analyses from countries such as China, Israel, the United States, Brazil, and Australia, and 20% are clinical trial articles from the United States. Results: In the 10 articles, it was evidenced that 80% (8/10) of the authors agree that the use of norepinephrine in patients with septic shock presented fewer cardiac adverse events, and decreased the arrhythmia rate, compared to the use of dopamine. Conclusions: The reviewed articles showed that norepinephrine is more effective than dopamine as it does not present adverse effects in the treatment of patients with septic shock, and they state that dopamine is not as effective compared to norepinephrine in the treatment of septic shock due to adverse effects such as cardiac arrhythmias and increased mortality.
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