Examinando por Materia "Therapy"

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    Effectiveness of isoniazid therapy compared to other therapies in treating latent tuberculosis infection
    (Universidad Privada Norbert Wiener, 2019-12-14) Torres Hilario, Zenovia Elena; Sánchez Parinango, Eva María; Pérez Siguas, Rosa Eva
    Objective: Systematize the evidence on the effectiveness of Isoniazid therapy in comparison with other therapies for the treatment of latent tuberculosis infection. Material and Methods: It is a systematic review, the articles were subjected to a critical review of the literature, using the Grade evaluation system, thus recognizing the degree of evidence, these studies were found in the databases: PubMed, Science direct, Cochrane , Epistemonikos. Of the 10 articles found, 40% (n= 4/10) are systematic reviews, 10% (n=1/10) are meta-analyses, 30% (n= 3/10) are randomized controlled trials and 20 % (n= 2/10) are a cohort study. Furthermore, these articles come from the USA (60%), followed by Canada (20%), then Australia (10%) and Spain (10%). Results: It was found that 100% (n=10/10) indicate that isoniazid preventive therapy for 6 months is as effective as other therapies for the treatment of infection with latent tuberculosis, however, all other therapies for being shorter showed greater adherence and fewer adverse effects compared to 6 months of isoniazid. Conclusion: The majority of the articles reviewed (10/10) report that isoniazid preventive therapy for 6 months is as effective as other therapies for the treatment of infection with latent tuberculosis, however, the other shorter therapies show greater adherence and fewer adverse effects.