Examinando por Materia "Uremic Toxins"

Mostrando 1 - 5 de 5

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Critical review: Effectiveness of prebiotic supplementation in reducing uremic toxins in chronic kidney disease undergoing hemodialysis
(Universidad Privada Norbert Wiener, 2023-03-21) Vásquez López, Maria Lourdes; León Cáceres, Johanna del Carmen
The secondary research titled “Critical Review: Effectiveness of Prebiotic Supplementation in Reducing Uremic Toxins in Chronic Kidney Disease on Hemodialysis” aimed to demonstrate the effectiveness of prebiotic (resistant starch) supplementation in reducing uremic toxins in CKD patients undergoing hemodialysis. The clinical question was: “Does prebiotic supplementation reduce the production of uremic toxins in adult CKD patients on hemodialysis?” The Evidence-Based Nutrition (NuBE) methodology was used, and information was sought from Pubmed, Scielo, Cochrane, Dialnet, and Redalyc, resulting in 598 articles. Ten were chosen for evaluation using the CASPE critical reading tool, and the randomized double-blind clinical trial titled “Resistant starch type-2 enriched cookies modulate uremic toxins and inflammation in hemodialysis patients: a randomized, double-blind, crossover, and placebo-controlled trial” was selected, which has an A I evidence level and a Strong Recommendation grade. The critical commentary highlights that prebiotic supplementation is an innovative alternative to reduce uremic toxins and improve the quality of life in CKD patients on hemodialysis.
Acceso abierto
Effect of dietary fiber on the reduction of uremic toxins in adult patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2022-05-25) Laura Ticona, María Elena; León Cáceres, Johanna del Carmen
Chronic kidney disease (CKD) develops due to gradual loss of kidney function. In CKD, a deficiency in dietary fiber intake is a factor that leads to intestinal dysbiosis contributing to uremic toxicity. The present secondary research aims to determine the effect of dietary fiber in reducing uremic toxins in adult patients with CKD. The Evidence-Based Nutrition (EBN) methodology was used. The information search was carried out in Pubmed, Scielo, Redalyc, finding 37 articles, 10 articles being selected, which have been evaluated by the CASPE critical reading tool, selecting the research entitled "The Role of Dietary Fiber Supplementation in Regulating Uremic Toxins in Patients With Chronic Kidney Disease: A Meta-Analysis of Randomized Controlled Trials". The critical commentary allowed to conclude that dietary fiber supplementation decreased the levels of IS, pCS, BUN and AU in patients with CKD, so dietary fiber supplementation is recommended in patients with CKD.
Acceso abierto
Effectiveness of probiotics in reducing uremic toxins in patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2019-11-17) Vargas Marcaquispe, Dina; Ibarra Noreña, Haydeé; Pretell Aguilar, Rosa María
OBJECTIVE: Systematize evidence on the effectiveness of probiotics in reducing uremic toxins in patients with chronic kidney disease. MATERIAL AND METHOD: The study is quantitative, with a systematic, observational and retrospective review design; of articles with full text, which identified their grade or quality of evidence according to the Grade System. Likewise, the population was made up of 10 articles that were obtained from the database. Of which 70% are of systematic review design and 30% of randomized clinical trials. RESULTS: Of the 10 articles reviewed, (10/10), 100% demonstrate the effectiveness of probiotics in reducing uremic toxins in patients with chronic kidney disease. CONCLUSIONS: 10 of the 10 articles respond that probiotics are effective in reducing uremic toxins in patients with chronic kidney disease (CKD); helping to slow the progression of kidney disease and improve heart health, as an adjuvant therapy for CKD, because they cost less and are more acceptable in kidney patients.
Acceso abierto
Revisión crítica: efecto de la suplementación con los probióticos en toxinas urémicas en pacientes con enfermedad renal crónica
(Universidad Privada Norbert Wiener, 2025-03-26) Galarza Barzola, Gabriela Frida; Ponce Castillo, Melissa
Cuando se proporcionan en las cantidades adecuadas, la suplementación con probióticos, microorganismos vivos, brinda beneficios a la salud del huésped, al disminuir la producción de toxinas urémicas y evitar el avance de la ERC. Esta segunda investigación denominada "Revisión crítica: "Resultado de la suplementación con probióticos en toxinas urémicas en pacientes con ERC", se creó para entender el beneficio de los probióticos en la disminución de las toxinas urémicas. Se plantea la interrogante clínica ¿Qué impacto tiene la suplementación con probióticos en las toxinas urémicas en pacientes con ERC? Aplica el enfoque de Nutrición Basada en Evidencia (NuBE). La recopilación de información se obtuvo de PUBMED, LILACS COCHRANE LIBRARY, obteniendo 48 publicaciones. De esto, 10 publicaciones han pasado a ser evaluados mediante el instrumento CASPE. Después de esto, fue seleccionado Ensayo Clínico Aleatorizado denominado "Suplementación con probióticos en la enfermedad renal crónica: un ensayo doble ciego, aleatorizado y controlado con placebo", basándose en la práctica del experto. El estudio crítico sugiere inferir que la suplementación con probióticos no logro disminuir las toxinas urémicas y los marcadores de inflamación. Así pues, es necesario seleccionar con cautela la terapia con probióticos en pacientes con HD. Es indispensable llevar a cabo más estudios que abordan el tratamiento con probióticos en individuos con enfermedad renal crónica.
Acceso abierto
Systemic review: Efficacy of probiotic supplementation in reducing nitrogenous waste and uremic toxins in patients with chronic kidney disease
(Universidad Privada Norbert Wiener, 2021-01-19) Rosario Rengifo, Pedro Miguel; Mauricio Alza, Saby Marisol
Objective: To know the effectiveness of probiotic supplementation in reducing nitrogenous waste and uremic toxins in patients with kidney disease. Materials and methods: Meta-analysis studies and randomized controlled trials were collected from virtual health journals including: Lilacs, BVS Minsa, and PubMed. They were included research evaluating the effect of probiotics on nitrogenous waste and uremic toxins in patients with chronic kidney disease. The GRADE approach was used to determine the quality of the research collected. Results: The information reported in relation to probiotic supplementation did not demonstrate a reduction in nitrogenous waste or uremic toxins, evident in 13 of the selected articles, in which a non-significant decrease was found or no variation was observed in the metabolites studied. Conclusions: It is concluded that the use of probiotics as adjuvant therapy in the nutritional management of chronic kidney disease has not shown proven effectiveness in reducing nitrogenous waste or uremic toxins, therefore it should not be used for that purpose.