Examinando por Materia "beta-Lactamas"

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Acceso abierto
Factores en la automedicación con antibióticos betalactámicos en usuarios adultos atendidos en boticas de la Avenida Gran Chimú – San Juan de Lurigancho 2021
(Universidad Privada Norbert Wiener, 2022-04-26) Pérez Cueva, Jessica Edith; Rivas Huatuco, Yesenia Edith; Alvarado Chávez, Britt
Objective: To determine the factors influencing self-medication with beta-lactam antibiotics among adult users at drugstores on Gran Chimú Avenue in San Juan de Lurigancho. Methods: This was a basic, descriptive, prospective, cross-sectional, and non-participatory observational study. A 17-item questionnaire was used as the data collection instrument and was applied to 300 users. Results: Of the 300 users who self-medicated, the sociodemographic factors were: 93% were between 18 and 59 years old, 55% were male, 71% had a higher education degree, 51.7% had 4 to 6 family members, and 52.3% were from a province. Regarding economic factors, 60.7% were employed, 74% had an income greater than S/ 950.00 soles, and 77.3% had health insurance. In terms of sociocultural factors, 47.3% self-medicated based on a family member's suggestion, 84% lacked the time to visit a health facility, and 87% were influenced by the internet. Conclusion: It is concluded that various factors, including sociodemographic, economic, and sociocultural factors, play a role in self-medication.
Acceso abierto
Factores predisponentes frente a la automedicación de macrólidos y betalactámicos en el contexto de la pandemia en pobladores adultos del distrito de Lurin – Lima Metropolitana semestre de enero a junio 2021
(Universidad Privada Norbert Wiener, 2022-01-17) Barreto Garcia, Mariella Brigitte; Reyes Altamirano, Cleydy Carolina; Ramos Jaco, Antonio Guillermo
Self-medication has been a practice for years, but cases increased during the COVID-19 pandemic. Antibiotics, particularly beta-lactams and macrolides, were among the most consumed drugs. The main objective of this research was to determine the relationship between predisposing factors and self-medication with beta-lactam and macrolide drugs during the current pandemic. Methodology: The study used a non-experimental type, a quantitative approach, and a hypothetical-deductive method. It was conducted in pharmaceutical establishments in the Lurín district, with a sample of 334 patients from January to June 2021. The data collection instrument was a questionnaire that was previously validated and consisted of eight dimensions. Results: The study sought a favorable relationship among social, cultural, and economic factors promoting self-medication. A bilateral asymptotic significance value of less than 0.05 was found for the variables of self-medication with macrolides and beta-lactams and predisposing factors. This evidence confirmed a relationship between the study variables, leading to the rejection of the null hypothesis and the acceptance of the alternative hypothesis. Furthermore, the correlation showed a moderate positive correlation that is statistically highly significant (r= 0.456; p=0.000<0.05). Conclusion: The relationship between predisposing factors and self-medication with macrolides and beta-lactams in the context of the pandemic among adult residents of the Lurín district, Metropolitan Lima, during the January to June 2021 semester, was highly significant and moderate positive.
Acceso abierto
La relación del consumo de betalactámicos con los efectos adversos gastrointestinales en personas que acuden al Puesto de Salud- Agustino, 2023
(Universidad Privada Norbert Wiener, 2025-02-27) Hoyos Burga, Yany Avelinda; Orellana Berrocal, Rosa Julia; Esteves Cárdenas, Verónica Liset
The objective was to determine the relationship between beta-lactam consumption and gastrointestinal adverse effects in people who go to the Health Post - Agustino, 2023. Methodology: the method was deductive, with a quantitative approach, the type of research was basic, non-experimental design, cross-sectional, prospective and correlational. The population was 320 users who went to the health post and the sample was 178 which was calculated with the finite population formula, to whom the survey technique was applied with the questionnaire as an instrument for collecting data that were statistically analyzed. Results: the respondents were 55,1% male, the most frequent age being 40 years or older 40,4% of the cases, as for the level of education, the majority were from secondary level (48,3%). It was observed that amoxicillin was consumed by 99,4%, in second place, appears amoxicillin / clavulanic with 96.1% and in third and fourth place ampicillin and cefuroxime were 86,0% and 53,9% respectively of the people who went to the Health Post - Agustino. There is a relationship between ampicillin consumption, dose and frequency with gastrointestinal adverse effects in people, similarly a low correlation of Cramer's V was found with values higher than 0,220. In addition, amoxicillin has no relationship because it was not statistically significant. Conclusion: It is concluded that there is a relationship between the consumption of ampicillin, the dose and the frequency of beta-lactams with gastrointestinal adverse effects.