Correlation between renal profile and the level of glycosylated hemoglobin in patients with diabetes mellitus treated at María Auxiliadora Hospital, 2017

Abstract

Transfusion therapy has helped reduce mortality and improve the quality of life for many cancer patients. The objective of this study was to determine the frequency of transfused blood components in patients with neoplastic diseases registered in the Blood Bank service at the Oncosalud Clinic from June 2016 to June 2018. We conducted a retrospective, descriptive, cross-sectional study. We included patients over 18 years old, with preneoplastic alterations, neoplastic diseases, or with recurrences and treatment control, who had received a full, complication-free transfusion.

We included 3,022 transfusion requests, of which 1,525 (50.5%) were women with an average age of 59.8±17.5 years, statistically not significant compared to men (65.3±14.1 years) (p=0.210). Both sexes predominantly required red blood cell concentrate (RBC) at 67.9%, followed by platelets (PLT) at 19.9%. The age group from 56 to 70 years demanded the highest amount of blood products (40.2%). In both periods, hematological neoplasms (49.1%) required the highest number of transfusions, followed by gynecological (16.3%) and gastrointestinal (15.1%) neoplasms. This study demonstrated a high frequency of transfused blood components (red blood cell concentrate and platelets), primarily in hematological neoplasms.

Se determinó el grado de correlación entre el perfil renal y el nivel de hemoglobina glicosilada en pacientes con diabetes mellitus atendidos en el Hospital María Auxiliadora 2017. Estudio observacional, analítico-correlacional, retrospectivo y transversal, cuya muestra estuvo conformada por 169 historias clínicas de pacientes con diabetes mellitus atendidos en el Hospital. El instrumento utilizado fue una ficha de recolección elaborada por el propio investigador; la información fue recopilada en el programa SPSS versión 25. El 57.4% de los pacientes en estudio eran del sexo masculino. La media de las variables resultaron: 1,05 mg/dL creatinina, 7,58 % hemoglobina glicosilada, 230,32 mg en 24 h microalbuminuria y 54,16 mg/dL para la urea. Los niveles con mayor porcentaje en las variables en estudio fueron: Hemoglobina glicosilada, 42% el nivel aceptable; microalbuminuria, 59.8% valores mayores a 30 mg/24 horas; Creatinina, 65,7% nivel normal; y Urea, 51.5% nivel normal entre los 15 a 40 mg/dL. Relación significativa entre la hemoglobina glicosilada y el perfil renal (p=0.485 con el nivel de creatinina, p=0.055 con el nivel de microalbuminuria y p=0.768 con el nivel de urea).