Relationship Between Lipid Profile and Atherogenic Indices with Glycated Hemoglobin Levels in Patients Attended at María Auxiliadora Hospital, 2017

Abstract

The objective was to determine the relationship between lipid profile and atherogenic indices with glycated hemoglobin levels in patients attended at the María Auxiliadora Hospital in 2017. Material and Methods: Observational, analytical, retrospective, cross-sectional study. Total cholesterol (TC), HDL cholesterol (cHDL), LDL cholesterol (cLDL), triglycerides (TG), and atherogenic indices: TC/cHDL, cLDL/cHDL, C-no HDL/cHDL were analyzed in 5562 blood sample results using the Chi-square statistical test. Results: The results for normal HbA1c showed recommendable levels of TC, cHDL, cLDL, and TG (72.5%, 32.2%, 68.3%, and 67.6%, respectively). The results for prediabetes HbA1c showed recommendable levels of TC, cHDL, cLDL, and TG (67.6%, 27.2%, 61.9%, and 60.7%, respectively). The results for diabetes HbA1c showed recommendable levels of TC, cHDL, cLDL, and TG (67.4%, 30.5%, 62.7%, and 57.4%, respectively). The atherogenic indices showed recommendable levels in all three groups. There was a significant relationship between HbA1c and TC (p<0.001), cHDL (p=0.016), cLDL (p<0.001), triglycerides (p<0.001), and the atherogenic indices TC/cHDL (p<0.001), cLDL/cHDL (p<0.001), and C-no HDL/cHDL (p<0.001). Conclusion: There is a significant relationship between the lipid profile, atherogenic indices, and HbA1c levels in patients attended at the María Auxiliadora Hospital in 2017.

El objetivo es determinar la relación entre el perfil lipídico e índices aterogénicos con el nivel de hemoglobina glicosilada en pacientes atendidos en el Hospital María Auxiliadora, 2017. Material y Métodos: Estudio observacional, analítico, retrospectivo, transversal. Se analizó colesterol total (CT), colesterol HDL (cHDL), colesterol LDL (cLDL), triglicéridos (TG); e índices aterogénicos: CT/Chdl, cLDL/cHDL, C-no HDL/cHDL, en 5562 resultados de muestras sanguíneas, utilizando la prueba estadística Chi Cuadrado. Resultados: Los resultados de HbA1c normal presentaron nivel recomendable de CT, cHDL, cLDL y TG (72.5%, 32.2%, 68.3% y 67.6%; respectivamente). Los resultados de HbA1c prediabetes presentaron nivel recomendable de CT, cHDL, cLDL y TG (67.6%, 27.2%, 61.9% y 60.7%; respectivamente). Los resultados de HbA1c diabetes presentaron nivel recomendable de CT, cHDL, cLDL y TG (67.4%, 30.5%, 62.7% y 57.4%, respectivamente). Los índices aterogénicos presentaron un nivel recomendable en los tres grupos. Hubo relación significativa entre HbA1c y CT (p<0.001), cHDL (p= 0.016), cLDL (p<0.001), triglicéridos (p<0.001) y los índices aterogénicos CT/cHDL (p<0.001), cLDL/cHDL (p<0.001) y C-no HDL/cHDL (p<0.001). Conclusión: Existe relación significativa entre el perfil lipídico e índices aterogénicos con el nivel de HbA1c en pacientes atendidos en el Hospital María Auxiliadora, 2017.