Examinando por Autor "Ñañez del Pino, Daniel"

Mostrando 1 - 20 de 55

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Adherencia a la terapia farmacológica y sus factores asociados en pacientes con tuberculosis del programa de TBC en un centro de salud de Lima Metropolitana, 2021
(Universidad Privada Norbert Wiener, 2022-01-17) Palacin Custodio, Maritza Lucia; Ñañez del Pino, Daniel
Currently, poor adherence to treatment for chronic diseases is a global problem of alarming magnitude. In Peru, where public hospitals are often precarious and medicines are scarce, medical staff are redoubling their efforts to keep patients on track with their treatments. This research aims to determine the relationship between adherence to pharmacological therapy and associated factors in patients with tuberculosis from the TBC program at a health center in Metropolitan Lima in 2021. The research methodology is based on a quantitative approach, with a basic study type, a correlational level, and a non-experimental, cross-sectional design. The population consists of 300 patients undergoing TBC treatment at Emergencia Grau Hospital from January to August 2021. The sample, obtained through a simple probabilistic sampling method, is 170 patients. Data will be collected using the survey technique. Accordingly, the research instruments consist of two questionnaires: the Therapeutic Adherence Scale (TAS) and the Questionnaire on Factors Associated with Therapeutic Adherence.
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Automedicación con antibióticos para tratamiento de SARS-CoV-2 y factores de riesgo en usuarios atendidos en boticas de la avenida 225 Pachacútec – Ventanilla, 2021
(Universidad Privada Norbert Wiener, 2021-08-03) Mayta Oré, Lizbeth Roxana; Maravi Conopuma, Guina Rocio; Ñañez del Pino, Daniel
The misuse of medications, such as antibiotics, carries significant consequences, increasing morbidity and mortality due to antimicrobial resistance, especially in the context of SARS-CoV-2. Objective: To describe how risk factors relate to self-medication with antibiotics for the treatment of SARS-CoV-2 in users served at drugstores on Avenida 225 Pachacútec, Ventanilla, in 2021. Methods: The research type was basic, deductive, with a quantitative approach and a descriptive-correlational, cross-sectional, and prospective design. Results: Of 234 users who presented with SARS-CoV-2 symptoms, 55.6% had a cough, 43.2% a sore throat, 41.9% a headache, and 38.5% a fever. The reasons for self-medication were a lack of time (49.6%), the high cost of medical care (45.7%), and saturated hospitals (44.0%). Pre-existing conditions included diabetes (12.4%), obesity (11.5%), and arterial hypertension (6.0%). Regarding drug interactions, 59.8% reported consuming other medications. Concerning toxicity, 71.4% self-medicated with antibiotics, and 6.0% had developed some type of allergy. Additionally, 48.3% consulted a pharmacist based on their symptoms. Conclusion: It was determined that risk factors were significantly related to self-medication with antibiotics for the treatment of SARS-CoV-2 in the users served at drugstores on Avenida 225 Pachacútec, Ventanilla, in 2021.
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Automedicación frente a síntomas de ansiedad en el contexto de COVID-19, en usuarios que acuden a una botica en los Olivos, Lima 2021
(Universidad Privada Norbert Wiener, 2022-05-20) Arias Anchihuay, Elisabet Fiorela; Manrique Carhuas, Pablo Rafael; Ñañez del Pino, Daniel
The context of the COVID-19 pandemic, which caused physical and mental harm to the population, motivated self-medication in some individuals to soothe their anxious state. Objective: To determine the relationship between self-medication for anxiety symptoms in the context of COVID-19 among users visiting a drugstore in Los Olivos, Lima, in 2021. Methodology: The study was deductive, basic, with a quantitative approach, and a non-experimental, descriptive, correlational, cross-sectional, and prospective design. Spearman's Rho analysis was performed to validate the hypothesis. Results: Of 384 users, 93.5% were aged 18–59, and 53.4% were female. It was determined that as anxiety symptoms increased, self-medication sometimes increased from 9.0% to 21.1%. A similar case was observed for self-medication by personal initiative, where the increase was from 7.5% to 33.3%. Self-medication without a medical prescription increased from 15.8% to 47.7%. The consumption of anxiolytics or antidepressants increased from 0.8% to 26.3% due to the rise in anxiety symptoms. Conclusion: A moderate relationship was determined to exist between self-medication for anxiety symptoms in the context of COVID-19 among users visiting a drugstore in Los Olivos, Lima, in 2021.
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Calidad de atención farmacéutica y satisfacción de los usuarios en la botica Emifarma, Huancabamba – Piura 2022
(Universidad Privada Norbert Wiener, 2023-02-16) Zegarra Monja, Alondra Esteffany; Cruz Neira, Keyla Alexandra; Ñañez del Pino, Daniel
The main objective of this research was to determine the relationship between the quality of pharmaceutical care and user satisfaction at the Emifarma pharmacy, Huancabamba – Piura, in 2022. The study was descriptive-correlational with an observational and cross-sectional design, involving a sample of 278 users who visited the Emifarma pharmacy. A pharmaceutical care quality questionnaire with 10 items and a user satisfaction questionnaire with 22 items based on the SERVQUAL model were used. The results showed that pharmaceutical care quality was regular (51.8%), and user satisfaction was medium (68.3%). To verify the correlation between both variables, Spearman's Rho test was applied, revealing a relationship between the quality of pharmaceutical care and user satisfaction, with a p-value of 0.00 and a moderate correlation strength of 0.416. Regarding the quality of pharmaceutical care, the dimensions showed good quality (55.8%) in pharmacotherapeutic counseling, regular quality (47.1%) in dispensing, and regular quality (56.5%) in pharmacotherapeutic follow-up. In terms of user satisfaction, medium satisfaction was prominent in reliability (55.8%), responsiveness (49.6%), and empathy (62.2%), while high satisfaction was observed in safety (50%) and tangibility (52.9%). The study concluded that there is a positive and moderate correlation between the quality of pharmaceutical care and user satisfaction at the Emifarma pharmacy, Huancabamba – Piura, in 2022, indicating that good quality leads to high user satisfaction.
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Calidad de servicio y satisfacción a usuarios que acuden a la farmacia de emergencia del Hospital III Suarez – Angamos (enero–agosto 2019) Lima – 2021
(Universidad Privada Norbert Wiener, 2021-08-10) Villegas Chiroque, Maria Julia; Muñoz Quispe, Jesús Eliseo; Ñañez del Pino, Daniel
Medical centers today are focused on meeting the needs of users and patients who seek quality service. This focus should be shared by all members of the institution, providing decentralized care. The objective of this descriptive, correlational, cross-sectional study was to determine the relationship between service quality and user satisfaction among patients visiting the emergency pharmacy at the Suarez-Angamos Hospital III in Lima, from January to August 2019. The population sample consisted of 13,790 users, and the required sample included 398 users. Two questionnaires based on the SERVQUAL model were developed: one with 20 closed questions for service quality, and another with 15 closed questions for user satisfaction. Both were scored using a Likert scale with values of 1–5 for service quality and 1–4 for user satisfaction. Data was processed using EXCEL and IBM SPSS Statistics 25. The results showed a service quality of 73.9% and a patient satisfaction of 49.75%. A relationship was found to exist between the two variables, with a moderate, direct, and significant correlation between service quality and user satisfaction. The Spearman's correlation coefficient was 0.495, with a p-value less than the significance level (p=0.0010 < 0.05). In conclusion, there is a direct link between the service quality provided and the satisfaction of users who visit the Suarez-Angamos Hospital III.
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Características de los medicamentos más vendidos y su variación en tiempos de COVID-19 en el establecimiento farmacéutico "Botica Napa", septiembre 2019–agosto 2020
(Universidad Privada Norbert Wiener, 2021-08-03) Sañac Romero, Richar; Ñañez del Pino, Daniel
The objective of this thesis was to determine the characteristics of the best-selling medications and their variation during the COVID-19 period at the BOTICA NAPA pharmaceutical establishment from September 2019 to August 2020. Methodology: This was an observational, descriptive, cross-sectional, and retrospective study. A total of 172,221 medications sold before and during the pandemic were evaluated and analyzed according to their Anatomical Therapeutic Chemical (ATC) classification and their intrinsic therapeutic value. Results: The most sold anatomical groups of medications were: anti-infectives for systemic use (19.56%), the nervous system (18.95%), and the respiratory system (14.39%). The most sold therapeutic groups were: antibacterials for systemic use (18.68%), analgesics (17.62%), anti-inflammatory and anti-rheumatic products (11.71%), and systemic antihistamines (10.40%). Furthermore, the intrinsic therapeutic value of the medications was 'high value' (78.78%), and 69.99% were monopharmaceuticals. The variation in the sales of the best-selling medications during the pandemic was very high, with the largest number of medications showing a sales variation of more than 100.00%. Conclusion: It was determined that the best-selling medications before and during the pandemic have a high value, are composed of a single drug, and their variation is very high across all anatomical and therapeutic groups.
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Características y nivel de cumplimiento de buenas prácticas de prescripción en recetas de antibióticos atendidas en boticas Perú de San Juan de Miraflores – Lima 2021
(Universidad Privada Norbert Wiener, 2021-08-13) Heredia Huarcaya, Johnny; Mochcco Aguilar, Flor; Ñañez del Pino, Daniel
Compliance with good prescribing practices is crucial for public health, as its application prevents negative consequences for patient health. Likewise, the characterization of antibiotics is a necessity for proper registration and control. The objective of this study was to determine the characteristics and the level of compliance with good prescribing practices for antibiotic prescriptions filled at Boticas Perú in San Juan de Miraflores, Lima, in 2021. Methodology: A quantitative, observational, descriptive, and cross-sectional approach was used. The technique was observation, and the instrument was a data collection form applied to a sample of 364 prescriptions. The data were analyzed with descriptive statistics of central tendency and presented in tables and figures. Results: The results indicate a higher prescription rate for antibiotics such as ciprofloxacin (19%), amoxicillin (17%), and azithromycin (10%). The most common route of administration was oral (74%), followed by parenteral (14%), and topical (12%). A higher percentage of potential adverse effects were of Type A (89%) compared to Type B (11%). Furthermore, there was a high compliance level (79%) for medication data, a medium compliance level (72.3%) for prescriber data, and a low compliance level (43.3%) for patient data. Conclusion: The level of compliance with good prescribing practices for antibiotics showed an overall medium level (64.9%), and a large percentage of prescriptions contained antibiotics.
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Conocimiento de los medicamentos para la disfunción eréctil en los usuarios que acuden a la botica Farmalux, Distrito La Victoria – Lima Metropolitana, en el periodo de septiembre 2021 a febrero 2022
(Universidad Privada Norbert Wiener, 2022-07-07) Reyna Nuñez, Jhonnatan Alvaro; León Orihuela, Edgar Jesús; Ñañez del Pino, Daniel
This study focuses on erectile dysfunction (ED) medications among users of the Farmalux drugstore in the La Victoria district of metropolitan Lima, from September 2021 to February 2022. The study was basic, using an analytical, descriptive-observational method and a non-experimental, cross-sectional design. The study population consisted of users aged 18 to 65 who acquired ED medications, considered to be an infinite population. The sample consisted of 385 people selected via a simple random sampling method. The main results showed that 96.9% were aware of the types of ED medications available. However, a significant number of users lacked knowledge about other aspects: 96.6% did not know about the adverse effects of ED medications, 98.2% were unaware of medications that contribute to the development of ED, and 92.5% did not know about the associated risk factors. It was concluded that the users visiting the Farmalux drugstore from September 2021 to February 2022 had an overall lack of knowledge about ED medications, with a rate of 88.6%.
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Conocimiento del almacenamiento y forma de eliminación de medicamentos en pacientes que asisten al centro de salud Santa Clara – distrito Ate vitarte – Lima Metropolitana 2022
(Universidad Privada Norbert Wiener, 2022-10-07) De La Cruz Añanca, Catherine Lucia; Roman Nateros, Rocio del Pilar; Ñañez del Pino, Daniel
The storage and disposal of medications within households has become a common practice that can pose risks to health safety. This study was carried out with the objective of identifying patients’ knowledge regarding medication storage and disposal at the Santa Clara Health Center. A descriptive study with a quantitative approach was conducted, surveying 320 patients. The findings revealed that knowledge about storage varied significantly. With respect to type of medication, 45.0% of patients demonstrated low knowledge, 32.5% medium, and 22.5% high. Considering pharmaceutical form, 20.3% had low knowledge, 31.3% medium, and 48.4% high. Knowledge about storage according to preservation conditions was low in 45.0% of participants. In terms of disposal practices, 87.2% of patients disposed of medications inadequately by type, and only 12.8% adequately. According to pharmaceutical form, 71.9% disposed of medications inadequately, while 28.1% did so adequately. Based on traditional habits, 65.6% eliminated medications adequately and 34.4% inadequately. In conclusion, 46.3% of patients demonstrated low knowledge regarding medication storage, and the disposal of medications at home was found to be mostly inadequate, reaching 73.4% during the 2022 study period.
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Conocimiento y actitudes de la automedicación con azitromicina en usuarios que acuden a la botica Cruz de Chalpón Los Olivos 2021
(Universidad Privada Norbert Wiener, 2022-01-17) Cañabi Congora, Ada Gisela; Hernández Camacho, Giovanna Patricia; Ñañez del Pino, Daniel
The objective was to analyze the level of knowledge and attitudes toward self-medication with azithromycin among users visiting the Cruz de Chalpón Drugstore in Los Olivos in 2021. Methodology: The research used a non-experimental, cross-sectional, and descriptive design. The sample consisted of 385 users. A validated survey was applied, which included open-ended questions for the knowledge variable and a Likert-scale questionnaire for the attitude variable. Results: In general, participants showed a medium level of knowledge. Specifically, the knowledge level was medium for self-medication with azithromycin (42.6%), the consequences of self-medication with azithromycin (45.2%), bacterial resistance with azithromycin (42.3%), and knowledge level based on demographic data (50.0%). Furthermore, users' attitudes were unfavorable (80.3%). Conclusion: The research allowed for an analysis of users' knowledge and attitudes, which showed that they have a simultaneous medium level of knowledge and an unfavorable attitude toward self-medication with azithromycin.
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Consumo de Bixa Orellana y su relación con la hipertrofia prostática benigna en pacientes que acuden a la Botica Palacios, en Moyobamba, San Martin 2025
(Universidad Privada Norbert Wiener, 2025-09-10) Flores Estela, Oferlinda; Guevara Infante, Yessica Jhudy; Ñañez del Pino, Daniel
The purpose of this study was to assess the consumption of Bixa orellana and benign prostatic disease among clients served at Botica Palacios, located in Moyobamba, San Martín, in 2025. The study was conducted cross-sectionally and correlationally, with a basic, quantitative approach that did not include experimentation. The sample, composed of 179 randomly selected individuals from a total of 335 men with BPH and over 40 years of age, was the community under study. For the research, a structured survey was used, consisting of two sections: one focused on sociodemographic data and consumption of the plant. The effects demonstrated a positive and statistically significant correlation between general consumption of Bixa orellana and BPH (rho = 0.690; p < 0.001). In addition, weak connections were found with specific dimensions such as the area used, the method of preparation, the duration and frequency of consumption, as well as the duration and severity of symptoms. It is concluded that, although the plant is frequently used in traditional practice, its consumption does not guarantee clear clinical benefits against BPH, making it necessary to continue with longitudinal research and clinical trials that evaluate its possible therapeutic effects.
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Consumo de chenopodium ambrosioides (paico) y su relación con parasitosis intestinal en pobladores que acuden al mercado San Carlos, SJL-Lima 2025
(Universidad Privada Norbert Wiener, 2025-11-18) Sánchez Moreyra, Lucy Ebilyn; Ñañez del Pino, Daniel
The overall objective of this study was to determine the relationship between the consumption of “Chenopodium ambrosioides” (paico) and intestinal parasitosis in residents who visited the San Carlos market in the district of San Juan de Lurigancho, Lima, in 2025. The population consisted of 300 adult consumers of paico, from which a sample of 169 participants was obtained, calculated using the formula for finite populations. The sampling was simple random probability, which ensured that all residents had the same probability of being selected. The method applied was hypothetical-deductive and quantitative, while the research was applied, with a non experimental, cross-sectional design and descriptive-correlational scope. The technique used was a survey, and the instrument was a structured questionnaire that collected sociodemographic information, as well as specific data on paico consumption, its forms of preparation, and the presence of intestinal parasitosis. The results showed that there was a significant negative relationship between paico consumption and intestinal parasitosis (Rho = –0.265; p = 0.001). Likewise, the consumption of leaves and stems and preparation as an infusion were associated with a lower prevalence of parasitosis, while the adverse events reported were mild and without significant association. In conclusion, paico was shown to be a traditional resource with therapeutic value against intestinal parasitic infections, constituting an accessible and culturally accepted alternative for the community studied.
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Consumo indiscriminado de medicamentos por pandemia COVID-19 en usuarios de boticas cercanas al mercado Ciudad de Dios San Juan de Miraflores marzo 2021
(Universidad Privada Norbert Wiener, 2021-10-07) Espinoza Medalla, Judith Eva; Calcina Laurente, Kelly Melissa; Ñañez del Pino, Daniel
The COVID-19 disease originated in China. The World Health Organization declared it a pandemic, leading to a public health crisis where the indiscriminate use of medications became a significant problem. The objective of this study was to determine how the COVID-19 pandemic relates to the indiscriminate consumption of medications among users of drugstores near the Ciudad de Dios market. Method: This was an inductive, quantitative, descriptive, non-participatory observational study. The sample consisted of 305 users. Results: 86.6% of respondents took medications without a prescription, and the most frequent signs and symptoms were headache and fever. The participants believed that the spread of the coronavirus disease was due to not wearing a mask, not washing hands, not social distancing, and not quarantining. They also believed that the lack of availability of care influenced their medication consumption. A high percentage self-medicated due to a lack of financial resources, for prevention, out of fear of contracting the disease, and due to the influence of the media. The most consumed medications were paracetamol and azithromycin. Conclusion: The COVID-19 pandemic is related to the indiscriminate consumption of medications.
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Consumo y efectos adversos del anticonceptivo oral de emergencia en mujeres de 18 a 40 años atendidas en la botica Jhire Farma, Ate Lima 2024
(Universidad Privada Norbert Wiener, 2025-02-27) Lino Salcedo, Cyndy Yesenia; Román Vásquez, Mario Pedro; Ñañez del Pino, Daniel
The objective of this study is to determine the relationship between the consumption and adverse effects of emergency oral contraceptives in women aged 18 to 40 years attending the "Jhire Farma" pharmacy in 2024. Methodology: This is a basic study with an observational design, a quantitative approach, a correlational level, and a cross-sectional cut. A survey was conducted with 218 users of emergency oral contraceptives, selected through systematic probabilistic sampling. Results: 46.8% of the users were between 25 and 32 years old. 40.4% had a low level of knowledge about the contraceptive, 39% had a medium level, and 20.6% had a high level. 52.8% consumed it based on recommendations from family or friends, and 44.4% did not use regular contraceptive methods. In the last year, 36.7% used it once, and 31.7% used it twice. In one month, 59.2% used it once, 33.2% up to twice, and 7.8% up to three times. 63.3% reported adverse effects, with the most common being nervous disorders (41.3%), gastrointestinal issues (28.9%), and menstrual irregularities (31.7%). Conclusion: A significant relationship was determined between the consumption and adverse effects of emergency oral contraceptives in women aged 18 to 40 years attending the "Jhire Farma" pharmacy in Lima in 2024. The presence of adverse effects increases from 49.6% to 94.1% when monthly use rises from one to three times.
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Consumo y uso tradicional de (physalis peruviana l.) Aguaymanto en personas que visitan el Mercado Gran Centro Comercial y Agropecuario Manuel Arturo Odría de Tarma – Junín, 2023
(Universidad Privada Norbert Wiener, 2024-10-14) Leyva Luna, Jennifer Dayan; Paucar Cueva, Percy Humberto; Ñañez del Pino, Daniel
The objective of this work was to evaluate the consumption and traditional use of the goldenberry (Physalis peruviana L.) in people who visit the Manuel Arturo Odría de Tarma – Junín large shopping and agricultural center market. A deductive study was carried out, with a quantitative approach, non-experimental basic type and observational scope using as an instrument a questionnaire that was carried out to 308 adults selected through a non-probabilistic sampling, accidental type and this instrument was applied for 7 days. The results found indicate that people consume the fruit Physalis peruviana L. only out of family habit and use it because it is a good antioxidant, however, they do not know about other benefits that this fruit can provide for health, making known its anti-inflammatory property (51,6%), helps reduce blood glucose levels (30,2%), treat cholesterol levels (31,5%), antioxidant (38,6%). It is concluded that people who visit the market indicate that they consume the fruit Physalis peruviana L. only out of family habit and they traditionally use it for its anti-inflammatory and antioxidant properties.
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Cumplimiento de buenas prácticas de prescripción en recetas medicas dispensadas en el hospital del distrito de Mala, provincia Cañete – Lima, noviembre 2021 a marzo 2022
(Universidad Privada Norbert Wiener, 2022-07-09) Eulogio Castillo, Katherine Zulay; Ñañez del Pino, Daniel
The objective was to determine compliance with good prescribing practices in medical prescriptions dispensed at the hospital in the Mala district from November 2021 to March 2022. Method: This study used a quantitative approach, a basic type, a non-experimental design, and a cross-sectional level. A total of 384 prescriptions were used for the study because they met the inclusion criteria. A checklist was used for data collection. Results: In Dimension 1, compliance was 52% for full name, 74% for professional registration number, 95% for signature, and 97% for stamp. In Dimension 2, 69% complied with full name and 75% with diagnosis. In Dimension 3, compliance was 75% for INN, 43% for concentration, 72% for pharmaceutical form, 69% for dose, and 74% for route of administration. In Dimension 4, compliance was 26% for legible handwriting, 72% for issuance date, and 22% for validation date. In Dimension 5, compliance was 72% for patient data, 61% for prescriber data, and 88% for medication data. In Dimension 6, compliance was 75% for INN, 56% for correct dose, and 61% for treatment duration. Conclusion: Good prescribing practices are not being followed at the hospital in the Mala-Cañete district, and improvements should be made for correct prescribing.
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Cumplimiento de las buenas prácticas de dispensación y acceso a medicamentos genéricos en las cadenas de boticas de Chorrillos 2022
(Universidad Privada Norbert Wiener, 2023-02-03) Perez Astete, Josue Daniel; Ñañez del Pino, Daniel
The research aims to determine the relationship between compliance with Good Dispensing Practices and access to generic medications in pharmacy chains in Chorrillos, 2022. The study design is applied, correlational in level, and non-experimental cross-sectional with a quantitative approach. A survey was conducted with a sample of 384 patients. The results from the 384 respondents showed a low level of 57% compliance with the Good Dispensing Practices manual and a high level of 41.1% access to generic medications in the pharmacy chains of Chorrillos in 2022. Among the dimensions: the presence of a Pharmacist demonstrated a low level of 71.9%, dispensing of medical prescriptions showed a low level of 56.5%, rational use of medications was low at 46.4%, the stock of essential medications showed a high level of 52.6%, sales strategies for medications were low at 53.4%, and the economic level demonstrated a high level at 58.9%. It is concluded that there is a relationship between these variables.
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Dolor somático asociado al uso de hierbas medicinales en adultos mayores a 40 años que acuden al Mercado Miguel Grau, Independencia, Lima, 2024
(Universidad Privada Norbert Wiener, 2025-04-11) Uriarte Jaimes, Jared Edinson; Vásquez Quispe, Leslie Evelyn; Ñañez del Pino, Daniel
The objective was to determine the relationship between somatic pain with the use of medicinal herbs in adults over 40 years of age who attend the Miguel Grau Market, Independencia. Method. The hypothetical deductive method was used, quantitative approach, non-experimental design, basic type, correlational scope, cross section, sample of 162 adults, through surveys and use of a questionnaire the data was collected, Spearman's Rho analysis was used to contrast the hypothesis. Results. Of 162 adults, 33.3% were aged between 51-60 years; somatic pain was mild in the arms and shoulders in 35.8% and in the head in 51.9%; It was moderate; in ankle and knee 46.3%; in the spine and/or hip 40.7%; in neck 43.8%. The Perception of somatic pain was mild, throbbing in 36.4% and burning in 38.9%; It was moderate in type of oppression 30.2%; numbness 38.9%. Use of medicinal herbs for relief of somatic pain; 27.2% used turmeric, 44.4% used fennel; 42% ginger, 25.3% nettle and 11.1% moringa. Part of the medicinal herb used; 18.5% the leaves; 11.1% the bark; 27.2% the seeds and 42% the flowers. In preparation of the medicinal herb, 24.7% in the form of a decoction, 27.2% in infusion; 42% topical and 25.3% macerated in ethanol. A significant relationship was identified between somatic pain and the use of medicinal herbs (p=0.000; rho=0.833). Conclusion. There was a high positive relationship between somatic pain and the use of medicinal herbs in adults over 40 years of age.
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Efecto antibacteriano del extracto hidroalcohólico de las hojas de solanum aphyodendron s. knapp (olmish) sobre staphylococcus aureus y bacillus cereus in vitro
(Universidad Privada Norbert Wiener, 2024-10-18) Narciso Mauricio, Flor de María; Valdivia Mora, Veronica Maciel; Ñañez del Pino, Daniel
The objective of the research is to determine whether the hydroalcoholic extract of the leaves of Solanum aphyodendron S. Knapp (Olmish) has an antibacterial effect on strains of Staphylococcus aureus ATCC 25923 and Bacillus cereus ATTC 11778, in vitro study. Methodology is hypothetical deductive whose quantitative approach, type of applied research with experimental design, cross-sectional and level of scope is explanatory. The phytochemical analysis was by "Phytochemical screening" and to determine the antibacterial activity was the Kirby Bauer method, which were taken concentrations of 25, 50 and 90 % of the extract. In the results, phenolic compounds, saponins, alkaloids, lactones, tannins, anthocyanins and flavonoids were found. In the microbiological test it was shown that the Staphylococcus aureus strain showed sensitivity to the three concentrations with average inhibition halos of 8,38, 11,10 and 13,42 mm; while Bacillus cereus only showed sensitivity to the concentration of 50 and 90 % with average inhibition halos of 8,63 and 13,02 mm. In conclusion, it was determined that the olmish leaf extract has an antibacterial effect on Staphylococcus aureus at the three concentrations and on Bacillus cereus only at 50 and 90 %, in an in vitro study.
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Efecto antiinflamatorio y analgésico del extracto hidroalcohólico de las hojas de Rumex cuneifolius Campd. “Romaza” mediante el método de edema subplantar y contorsiones abdominales en ratones albinos (Mus musculus)
(Universidad Privada Norbert Wiener, 2019-03-08) Sánchez Porras, Katheryne; Zavala Villanueva, Hellen Katerine; Ñañez del Pino, Daniel
In this study, the anti-inflammatory and analgesic effects of the hydroalcoholic extract from the leaves of Rumex cuneifolius Campd., known as "Romaza," were evaluated using the subplantar edema and abdominal writhing methods in albino mice (Mus musculus). Materials and Methods: A hydroalcoholic extract was obtained by maceration with 70% ethanol. The anti-inflammatory effect was assessed using the 1% albumin-induced subplantar edema method. The mice were divided into a Control Group, a diclofenac group (50 mg/kg), a dexamethasone group (4 mg/kg), and a hydroalcoholic extract group at doses of 50, 100, and 150 mg/kg. The analgesic effect was evaluated using the 0.8% glacial acetic acid-induced abdominal writhing model. The mice were divided into a Control Group, a paracetamol group (300 mg/kg), a tramadol group (40 mg/kg), and a hydroalcoholic extract group at doses of 50, 100, and 200 mg/kg. Results and Conclusion: The extract showed solubility in both ethanol and methanol. The qualitative phytochemical analysis revealed the presence of primary metabolites (carbohydrates and amino acids) and secondary metabolites (phenolic compounds, flavonoids, steroids and/or triterpenes, sesquiterpene lactones, quinones, and alkaloids). The study determined that the ideal dose for the anti-inflammatory effect was 100 mg/kg, with an effectiveness of 94%. The analgesic effect was confirmed at a dose of 100 mg/kg, showing a 75% effectiveness. In conclusion, the hydroalcoholic extract from the leaves of Rumex cuneifolius Campd. "Romaza" demonstrates both anti-inflammatory and analgesic effects.