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Examinando por Autor "Llahuilla Quea, José Antonio"

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    La adulteración y calidad desinfectante del alcohol expendido en oficinas farmacéuticas y otros establecimientos comerciales, Lima – Cercado, setiembre 2020
    (Universidad Privada Norbert Wiener, 2022-05-19) Vargas Espinal, Maribel Juvenalda; Laureano Peña, Haydee Sonia; Llahuilla Quea, José Antonio
    The methodology used consisted of a random probabilistic sampling of 32 samples of 96° ethyl alcohols in 1 L bottles sold in pharmaceutical offices (sample B: 15 samples from drugstores and pharmacies) and other commercial establishments (sample A: 17 samples from small shops, shopping centers, and street vendors). Methanol was identified using the chromotropic acid reaction method. A sensory evaluation was conducted according to Peruvian Technical Standard 211.007:2014. The determination of physicochemical parameters (pH, alcoholic strength, and density) was performed according to the United States Pharmacopeia and Peruvian Technical Standard 319.229:2014. Disinfectant effectiveness was determined in accordance with the UNE-EN 1040 method for chemical antiseptics and disinfectants. The results identified positive methanol results in 13.3% of the B samples and 11.76% of the A samples. The alcoholic strength showed results lower than 96°, with an average of 93 in the B samples and 79 in the A samples. Additionally, the disinfectant effectiveness in the sample with the lowest alcoholic strength for group B showed a bactericidal activity greater than 99.99% at 30 seconds of contact against the microorganisms S. aureus and P. aeruginosa, while for group A, no bactericidal activity was observed.
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    Análisis del consumo de café y su relación con los efectos en la salud en personas con hipertensión arterial que acuden a boticas de la urbanización Los Alisos. Callao, 2024
    (Universidad Privada Norbert Wiener, 2025-04-11) Bonilla Mundaca, Lucerito Mayde; Mamani Yauyos, Julia Cristina; Llahuilla Quea, José Antonio
    Coffee has established itself as one of the most popular and widely consumed beverages worldwide and has been the subject of studies on its impact on cardiovascular health, especially blood pressure. Despite its high prevalence, the effects of caffeine on the risk of hypertension remain uncertain. Some studies suggest that regular coffee consumption may increase this risk, while others find no significant relationship. This lack of consensus is of concern, as hypertension is a key factor in cardiovascular disease, a major cause of global morbidity and mortality. Objective: “To evaluate the relationship between coffee consumption and health effects in people with arterial hypertension”. Methodology: This basic research used a quantitative approach and a hypothetical-deductive method, with a non-experimental cross-sectional design, whose scope was descriptive-correlational, through the application of 384 surveys to people with arterial hypertension who consume coffee and go to the different drugstores in the Los Alisos urbanization, Callao. Results: A direct and significant relationship was obtained (Rho=0.512), indicating that greater coffee consumption (time, frequency and type) is related to greater health effects. Conclusion: Coffee consumption is related to health effects in people with arterial hypertension who go to the drugstores in the Los Alisos urbanization, supported by the p value <0.05, rejecting the null hypothesis.
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    Consumo de bebidas energizantes y factores de riesgo cardiovascular en estudiantes de Farmacia de la Universidad Wiener-Lima 2023
    (Universidad Privada Norbert Wiener, 2023-11-20) Kanashiro Kakutani, Mary Ann; Solórzano Chávez, Ninoshtka Steffi; Llahuilla Quea, José Antonio
    This study aimed to determine the relationship between the consumption of energy drinks and cardiovascular risk factors in Pharmacy students at Wiener University, Lima 2023. Methodology: A cross-sectional, correlational, non-experimental study was conducted. The population consisted of 780 students, of whom 260 were surveyed. A reliability test was performed using the test–retest technique, where the results of Cramer’s V coefficient were higher than 0.64, indicating that the instrument was reliable. Results: A significant difference was observed in the percentage of consumers with high cholesterol (33.3%) compared to non-consumers (18.8%). The relationship between risk factors and the type of energy drink showed a higher percentage of elevated cholesterol among those who consumed Volt (36.4%) and Monster (57.1%). Regarding reasons for consumption, 25% indicated they used energy drinks to stay alert, and some presented elevated glucose levels. Consumers also reported symptoms such as palpitations (35.6%), anxiety (37.8%), and insomnia (11.1%). Regarding behavioral/modifiable factors, a high percentage of alcohol consumption (56.7%) was associated with energy drink consumers, while the practice of physical activity was higher among non-consumers (82.9%). Conclusion: It was determined that there is a relationship between energy drink consumption and cardiovascular risk factors.
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    Consumo de psicoestimulantes lícitos en estudiantes de la Facultad de Farmacia y Bioquímica de la Universidad Privada Norbert Wiener. Lima 2023
    (Universidad Privada Norbert Wiener, 2023-09-21) Guerrero Gonzalo, Yerika Marisol; Sihuay Salazar, Edy Erik; Llahuilla Quea, José Antonio
    The present study was conducted with the objective of evaluating the consumption of legal psychostimulants among students of the Faculty of Pharmacy and Biochemistry at Norbert Wiener Private University. To measure the study variable, five dimensions were considered. The research method used was deductive, with a quantitative approach and a non-experimental and cross-sectional design, at a descriptive level. Data obtained from a sample of 353 students were processed using the statistical program SPSS version 26, and graphs and tables were generated in Excel version 2019. The results revealed that coffee is the most commonly consumed legal psychostimulant in beverage form, while modafinil and methylphenidate are less commonly used. Regarding the purpose and perception of consumption, less than 50% of students use psychostimulants to reduce stress, increase concentration, reduce fatigue, enhance the feeling of well-being, or reduce sleep. Additionally, less than 45% reported experiencing positive effects related to the purpose for which they were consumed. Furthermore, the most commonly reported adverse effects associated with psychostimulant consumption were insomnia, anxiety, and headache.
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    Consumo de sustancias ilícitas en delito de violencia familiar en informes del Laboratorio de Química y Toxicología Forense de la Dirección de Criminalística de la Policía Nacional del Perú durante el año 2020
    (Universidad Privada Norbert Wiener, 2022-05-18) Alza Rios, Freddy William; Hancco Guerrero, Gisella; Llahuilla Quea, José Antonio
    This research employed a quantitative approach, with a descriptive scope and a cross-sectional-retrospective observational design. A sample of 228 reports was used, which were analyzed according to sex, age, place of origin, and positive results for illicit substances consumed (cocaine and marijuana). A data collection form was used as the instrument. Results: According to sex, marijuana consumption was 82.8% among males and cocaine consumption was 42.1% among females. By age, those aged 16 to 27 accounted for 91.7% of marijuana consumption, while those aged 40 to 65 accounted for 61.8% of cocaine consumption. By place of origin, the most representative districts for marijuana consumption were Callao (14.5%), San Juan de Lurigancho (13.4%), Comas (7.0%), and others (21.0% in 18 districts). Cocaine consumption was similarly highest in Callao (17.1%), San Juan de Lurigancho (11.4%), Comas (5.7%), and others (17.1% in 18 districts). Overall, 186 reports showed marijuana consumption (81.6%), and 70 reports showed cocaine consumption (30.7%) of the illicit substances.
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    Determinacion de medicamentos falsificados emitidos en las alertas de DIGEMID en el Perú 2012–2020
    (Universidad Privada Norbert Wiener, 2022-05-19) Allcca Rios, Giovanna Carolina; Quispe Yuyarima, Janeth Vanessa; Llahuilla Quea, José Antonio
    The objective was to determine the counterfeit medications issued in DIGEMID alerts in Peru from 2012 to 2020. Methodology: The research used a non-experimental descriptive design. Results: Among the counterfeit medications issued in DIGEMID alerts, Dolocordralam Extra Forte had the highest percentage at 5.3%, followed by Panadol Antigripal (4.8%) and Gravol 50 mg (4.2%). In the ATC classification, the musculoskeletal system led with 33.4%. By pharmaceutical form, tablets took the first place with 42.4%. By generic and/or commercial name classification, commercial (brand) names led with 99.24%. By department, Lima obtained the highest percentage with 69.3%, and the largest year-on-year increase was in 2013 with 2400%. Conclusions: The most counterfeited medication is Dolocordralam Extra Forte, and the years 2013 and 2016 showed the highest counterfeiting of medications in Peru.
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    Determinación de una técnica selectiva por cromatografía en capa fina para identificación de benzodiacepinas. Diciembre 2017
    (Universidad Privada Norbert Wiener, 2018-12-05) Jiménez Martínez, Laura Mónica; Rodriguez Gariza, Yessica; Llahuilla Quea, José Antonio
    The consumption of benzodiazepines is closely related to medico-legal aspects, as it is associated with criminal acts such as theft, crimes against sexual integrity, doping, and, from a clinical-legal perspective, dependence. Objective: To determine a selective technique by Thin-Layer Chromatography (TLC) for the identification of benzodiazepines. Method: Thin-layer chromatography was employed as a selective identification technique for benzodiazepines. Urine samples were collected from 26 healthy volunteers who had previously been administered benzodiazepines. The analysis was conducted in the toxicology laboratories of Norbert Wiener University and the National University of San Marcos (UNMSM). Results: Thin-layer chromatography tested positive for benzodiazepines and other substances (phenobarbital and phenytoin) in 80% of the urine samples analyzed. It is suggested that confirmatory techniques, such as gas chromatography–mass spectrometry (GC-MS), be used. Conclusion: Thin-layer chromatography was determined to be a highly sensitive technique, but not specific for benzodiazepines.
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    Determinación del consumo de marihuana y cocaína en alumnos del quinto año de secundaria del colegio José María Arguedas, Santa Anita, julio–diciembre, 2019
    (Universidad Privada Norbert Wiener, 2020-11-04) Espinoza Castro, Eugenia Rosa; Llahuilla Quea, José Antonio
    This research on the consumption of marijuana and cocaine was conducted in the Santa Anita District during the school period from July to October 2019. Its objective was to determine the consumption of cocaine and marijuana among fifth-year high school students at the José María Arguedas school. Regarding materials and methods, the research approach was qualitative-quantitative, as it involved laboratory analysis of urine samples and the use of academic grades for correlation. The methodologies used in this study were the Ontrak TesTstik Rapid Test for detecting cocaine and marijuana in urine samples and the Accu-Tell 2-drug Rapid Test (COC-THC). The population consisted of 59 students from Sections A and B of the fifth year of secondary education at the school. A sample of 38 students was obtained, as they had parental consent for urine sample collection. The results showed 5 users in Section A and 6 users in Section B. In Section A, 3 were male and 2 were female, while in Section B, 4 were male and 2 were female. It is concluded that there are students who consume marijuana and cocaine, and these students have grades below the average of 13.5. This consumption has a simple relationship with academic performance.
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    Evaluación de plomo y cadmio en papas fritas y su riesgo toxicológico en los consumidores de diez pollerías conocidas del Cercado de Lima. Setiembre–noviembre 2019
    (Universidad Privada Norbert Wiener, 2020-08-12) Guimarey Martin, Mercedes Tatiana; Reategui Curimozon, Judy; Llahuilla Quea, José Antonio
    The purpose of our research work is to evaluate the levels of lead and cadmium in French fries and, consequently, the toxicological risk to consumers in ten well-known rotisserie chicken restaurants (“pollerías”) in the district of Cercado de Lima. A total of 64 samples, each equivalent to 250 g of French fries, and 370 surveys were collected to assess the toxicological risk. The concentration of metals was determined using the Graphite Furnace Atomic Absorption Spectrophotometry method at CICOTOX. The results showed lead concentrations ranging from a minimum of 0.0040 mg/kg to a maximum of 0.0463 mg/kg, with an average of 0.073 mg/kg. For cadmium, the minimum was 0.03230 mg/kg, the maximum 0.81020 mg/kg, and the average 0.21100 mg/kg. Based on these concentrations, the estimated exposure dose was calculated as DE Pb = 0.0000000052 mg/kg/day and DE Cd = 0.0000000151 mg/kg/day. In conclusion, the concentration of lead (0.0073 mg/kg) in French fries was significantly lower in comparison with cadmium (0.2110 mg/kg), which was significantly higher than the maximum permissible limit established by the CODEX STAN 193-1995 of the WHO/FAO (0.1 mg/kg). According to the toxicological risk assessment methodology of PAHO/WHO, in the district studied there is evidence of a minimal toxicological risk from exposure to the analyzed factors.
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    Evaluación de riesgo toxicológico en agua potable destinada para consumo humano con posibles concentraciones de plomo, mercurio y arsénico en el distrito de la Unión Leticia, 2023
    (Universidad Privada Norbert Wiener, 2024-09-04) Maldonado Mendoza, Bianca Iris; Llahuilla Quea, José Antonio
    The purpose of the work was to determine the concentrations and risks of lead, mercury, and arsenic toxicity in drinking water for human consumption in the district of La Unión Leticia in 2023. For the analysis of the water, inductively coupled plasma mass spectrometry (ICP-MS) was used, and the development of a method to assess the health risks determined an average lead concentration of 0.00031 mg/L, with a minimum value of 0.00013 mg/L and a maximum value of 0.00013 mg/L. It was done, 0.00103 mg/L, not exceeding the permissible value according to the WHO and water quality standards. The mercury concentration was 0.00002 mg/L with a minimum value of 0.00001 mg/L and a maximum value of 0.00002 mg/L. In accordance with the WHO and water quality standards, it was finally determined The average arsenic concentration was determined to be 0.02745 mg/L, with a minimum of 0.022523 mg/L and a maximum of 0.03300 mg/L. This exceeds the regulatory and permitted limits for water quality and the WHO. This concentration was applied to the health risk assessment, resulting in a PI < 1. This indicates a risk of arsenic toxicity in the drinking water for human consumption in the district of La Unión Leticia in the year 2023.
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    Evaluación de riesgo toxicológico en personas expuestas, que consumen Beta vulgaris “Betarraga” cruda y cocida con posibles concentraciones de plomo y cadmio comercializada en el mercado de Chancay – Huaral, Lima 2019
    (Universidad Privada Norbert Wiener, 2021-02-06) Tarazona Guerrero, Janelle del Carmen; Condori Caceres, Soledad; Llahuilla Quea, José Antonio
    The agricultural soils of the Chancay–Huaral river basin are located in areas close to industrial centers, and these industries are characterized by emitting high concentrations of metals such as lead and cadmium. Toxicity studies on plant organisms cultivated in these soils are scarce, and it is unknown whether they may produce toxic effects. The vegetables cultivated in these soils may be exposed to deposits of toxic substances from nearby sources such as air, soil, or irrigation with contaminated water, thus constituting another point of contact for exposure in the population of the Chancay area. Accordingly, the objective of this study was to evaluate the toxicological risk in individuals who consume raw and cooked Beta vulgaris “beetroot” with possible concentrations of lead and cadmium commercialized in the Chancay market. For this purpose, beetroot samples sold in the Chancay market were collected, and the concentrations of lead and cadmium were determined by graphite furnace atomic absorption spectrophotometry. The beetroot samples presented average concentrations of lead of 4.45 µg/kg in cooked samples, while in raw samples the average was 10.32 µg/kg. With respect to cadmium, the average concentration was 2.67 µg/kg in cooked beetroot and 2.62 µg/kg in raw beetroot, all below the permissible limits. As a result of the toxicological risk assessment in individuals exposed to raw or cooked Beta vulgaris “beetroot,” a hazard index with values below 1 (HI < 1) was obtained. In conclusion, there is a low toxicological risk to health in the population of Chancay who consume raw and cooked beetroot with the presence of cadmium and lead at concentrations that do not exceed the permissible limits established by the Codex Alimentarius.
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    Evaluación toxicológica de cadmio, plomo y arsénico en suelo agrícola y rábano (Raphanus sativus) en zona Huachipa – Nievería distrito Lurigancho – Chosica. Lima. 2022
    (Universidad Privada Norbert Wiener, 2023-07-20) Nuñez Pebe, Walter Federico; Llahuilla Quea, José Antonio
    The objective of this study was to determine the toxicological concentrations of cadmium, lead, and arsenic in agricultural soil and radish (Raphanus sativus) in the Huachipa-Nievería area of the Lurigancho-Chosica district, 2022. Methodology: The method used was hypothetical-deductive, with a quantitative approach. It was a basic, non-experimental, correlational, and cross-sectional study at a descriptive level. Five soil samples were collected according to the Agricultural Soil Sampling Manual from MINAM to conduct this study. The study area was 300 m², and radishes were collected from the same points. The analytical method was performed in a laboratory using an ICP-OES device to provide concentration values for cadmium, lead, and arsenic in soil and radish. Results: Statistical tests were performed: T-student tests for soil and radish. Soil: Cadmium concentrations were determined with p=0.00 < 0.05; lead concentrations, p=0.00 < 0.05; arsenic concentrations, p=0.003 < 0.05. Therefore, cadmium, lead, and arsenic exceed the ECA limits for soil. Radish: Cadmium concentrations, p=0.096 > 0.05; lead concentrations, p=0.025 < 0.05; arsenic concentrations, p=0.49 > 0.05. Thus, cadmium and arsenic do not exceed permissible limits, while lead exceeds the permissible limit set by the Codex Alimentarius. Conclusion: It was found that radishes had lead concentrations in the soil that exceeded the limits allowed by the Codex Alimentarius.
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    Factores asociados al consumo de bebidas alcohólicas en estudiantes de farmacia y bioquímica de la Universidad Privada Norbert Wiener, Perú 2023
    (Universidad Privada Norbert Wiener, 2024-07-10) Cabrera Contreras, Jhon Carlos; Serrano Misaray, Karl Bryan; Llahuilla Quea, José Antonio
    To determine the factors most frequently associated with the consumption of alcoholic beverages among Pharmacy and Biochemistry students at Norbert Wiener Private University, Peru 2023. A quantitative, non-experimental, deductive, basic, descriptive, and cross-sectional approach was applied. It was described that the most frequent personal factors are: age group 20 to 25 years (39.6%), gender male (61.8%), studying and working (61.1%), single marital status (50%), minimum wage income (37.1%), and students in the 9th semester (22.1%). It was determined that the most frequent family factors are: students living alone (33.6%), psychological abuse (27.9%), family problems (71.8%), and emotional problems (70%). Social factors are: students with good relationships with classmates (46.1%), those who attend social gatherings twice a week (33.2%), and regarding sources of information, friends (42.1%). It was determined that the factors most frequently associated are: personal factors, family factors, and social factors, and the consumption of alcoholic beverages among students.
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    Factores asociados al consumo de benzodiacepinas en estudiantes del octavo y noveno ciclo de la facultad de farmacia y bioquímica de la Universidad Norbert Wiener Lima, 2023
    (Universidad Privada Norbert Wiener, 2025-03-03) Sanchez Ricaldi, Sadith Kimverli; Zea Yauce, Stephanie Lucero; Llahuilla Quea, José Antonio
    La investigación tuvo por objetivo Determinar la relación entre los factores asociados y el consumo de benzodiacepinas en estudiantes del octavo y noveno ciclo de la facultad de Farmacia y Bioquímica de la Universidad Norbert Wiener Lima, 2023. La metodología de estudio básico, de nivel correlacional, de corte trasversal y de diseño no experimental; la muestra fue de 255 alumnos de octavo y noveno ciclo de la facultad de Farmacia y Bioquímica, la técnica fue la encuesta y el instrumento el cuestionario; se realizó un análisis descriptivo, no se utilizaron inferencia estadística; interpretaremos la hipótesis directamente según la magnitud del coeficiente de asociación (V de Cramer). Con respecto a los resultados, se obtuvo que la situación laboral presentó una pequeña relación con el nivel de conocimiento (V de Cramer = 0,299) y la zona tiene relación pequeña con el consumo de benzodiacepinas (V de Cramer = 0,221); el tercio superior presentó una moderada correlación con el nivel de conocimiento (V de Cramer = 0,473) y las actividades extracurriculares presentó una correlación pequeña con el consumo de benzodiacepinas (V de Cramer = 0,109); los hábitos y actitudes negativas presentó una pequeña correlación con el nivel de conocimiento (V de Cramer =0,219) y los trastornos emocionales presentaron una correlación moderada con el consumo de benzodiacepinas (V de Cramer =0,436). Se concluye que, los factores asociados tienen relación moderada con el consumo de benzodiacepinas en estudiantes del octavo y noveno ciclo de la facultad de Farmacia y Bioquímica de la Universidad Norbert Wiener Lima, 2023.
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    Fitoterapia y factores asociados en afecciones respiratorias agudas de los pobladores del AA. HH La Encantada, grupo 1 en Villa el Salvador, Lima 2023
    (Universidad Privada Norbert Wiener, 2025-09-18) Chiara Condori, Yahaira Lucía; Díaz Vargas, Ilanit; Llahuilla Quea, José Antonio
    El presente estudio tuvo como objetivo “determinar la relación entre fitoterapia en afecciones respiratorias agudas y factores asociados en los pobladores del AA. HH La Encantada grupo 1 en Villa el Salvador, Lima 2023.”. La metodología se abordó a través del método deductivo, enfoque cuantitativo, diseño no experimental, correlación, de tipo básica y transversal. La muestra estuvo conformada por 208 residentes, a quienes se aplicó un cuestionario estructurado, elaborado y validado por los investigadores. Los datos fueron analizados mediante la prueba estadística Chi cuadrado, encontrándose los siguientes resultados: un valor de 3.285 para la variable “enfermedades respiratorias agudas” y 1.454 para “síntomas”. En cuanto a los factores demográficos, se obtuvo un valor de 0.845 para “ingresos económicos” y 3.856 para “seguro médico”. Se concluye que la fitoterapia mostró una efectividad del 99.1 % como tratamiento para las afecciones respiratorias agudas en la población estudiada.
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    Identificación de sustancias de corte en drogas cocaínicas en el Departamento de Química y Toxicología Forense de la Dirección de Criminalística de la Policía Nacional del Perú – Lima 2023
    (Universidad Privada Norbert Wiener, 2024-02-29) Gutierrez Seclen, Juliana Marisol; Llahuilla Quea, José Antonio
    The objective of this study was to identify cutting agents in cocaine-based drugs analyzed at the Department of Chemistry and Forensic Toxicology of the Criminalistics Directorate of the Peruvian National Police (PNP). The methodology employed was descriptive, with a quantitative approach, classified as basic, non-experimental, and cross-sectional. The population consisted of cocaine-based drugs, from which a sample of 217 units was drawn out of 500, using a simple random probabilistic sampling method. Identification of cutting agents was carried out through a standardized preliminary identification test and confirmed using the GC/MS analytical technique. Preliminary results indicated that the most common inactive cutting agents were reducing sugars (13%) and starch (11%). Additionally, 4% of the samples produced false positives. Among the active cutting agents, lidocaine and phenacetin showed the highest incidence (15%). In conclusion, the identified cutting agents included caffeine, lidocaine, phenacetin, ketamine, levamisole, starch, and reducing sugars.
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    Identificación del riesgo toxicológico de plomo en agua consumida por los pobladores del centro poblado rural "Guayabo", distrito de Pachacamac. Octubre –noviembre, 2019
    (Universidad Privada Norbert Wiener, 2021-05-21) Pérez Maraví, Ana Isabel; Llahuilla Quea, José Antonio
    The objective of this research thesis was to identify the toxicological risk of lead in water consumed by the residents of the 'Guayabo' rural town center in the Pachacámac district. The Atomic Absorption Spectrophotometry method was used for water analysis, and the Health Risk Assessment methodology was developed. The average lead concentration was 0.095 mg/L±0.014 mg/L, with a minimum value of 0.070 mg/L and a maximum value of 0.113 mg/L. These values exceed the Permissible Limit Values (PLVs) of the WHO and the Water Quality Regulation. Following the concentration measurements, the Health Risk Assessment was applied, calculating the exposure dose, which was 0.002714 mg/kg/L for adults and 0.0095 mg/kg/L for children aged 4 to 8 years. The exposure factor was 1. The hazard quotient (HQ) determined was 0.452 for adults and 1.583 for children. Conclusion: No toxicological risk exists for adults; however, a toxicological risk does exist for children, as the HQ quotient is greater than 1.
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    Manejo de plaguicidas y su relación con los síntomas neurotóxicos en los agricultores del distrito de Pachacamac, 2025
    (Universidad Privada Norbert Wiener, 2025-11-04) Escalante Ccoillo, Miguel Angel; Maldonado Saire, Yessabel Lucero; Llahuilla Quea, José Antonio
    The objective of the study was to determine the relationship between pesticide management and neurotoxic symptoms in farmers from Tambo Inga, Pachacamac district, 2025. The method used was descriptive correlational, with a quantitative approach; in addition, the type of study was basic, also, prospective, cross-sectional and observational; non-experimental, descriptive - correlational design. The population consisted of 150 farmers from Tambo Inga, Pachacamac district, and the selected sample consisted of 120 farmers, who were chosen through non-random convenience sampling and meeting the proposed selection criteria. The technique used was the survey, using in turn specific questionnaires for the evaluation of the variables; in addition, these were validated by expert judgment and denoted acceptable reliability according to Cronbach's Alpha. Results: It was observed that the majority of farmers presented no neurotoxic symptoms and adequate pesticide management (82.5%), while only 16.7% of farmers presented neurotoxic symptoms, despite adequate pesticide management. Furthermore, the correlational analysis of the variables found a correlation coefficient (Spearman's Rho) of -0.199 (p=0.029). Likewise, the correlational analysis between the dimensions of pesticide management (general knowledge, storage, and personal protection) and neurotoxic symptoms showed the same results, with negative and significant relationships. Conclusion: It was determined that there is a negative and significant relationship between pesticide management and neurotoxic symptoms; that is, it allows us to deduce that as pesticide management improves, neurotoxic symptoms in farmers decrease slightly, or vice versa.
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    Nivel de conocimiento acerca de la contaminación generada por la eliminación de residuos farmacéuticos del personal de farmacias y boticas del Rímac, 2022
    (Universidad Privada Norbert Wiener, 2023-04-27) Cabezas Huaman, Esmila Elva; Montalvo Vera, Maria Ysabel; Llahuilla Quea, José Antonio
    The general objective of this study was to determine the level of knowledge about the contamination generated by the disposal of pharmaceutical waste among pharmacy and drugstore personnel in Rímac. The method used was deductive, with a quantitative approach, basic type, and non-experimental design. The level of knowledge was measured by applying a questionnaire to 82 respondents. Results: The findings showed that 78.05% had a medium level of knowledge regarding the contamination generated by the disposal of pharmaceutical waste. Regarding the dimensions, the pharmaceutical form dimension showed a high level, while the dimensions related to the impact on the ecosystem and the importance of proper disposal showed a medium level, and the disposal practices dimension showed a low level of knowledge. Conclusion: The study participants demonstrated a medium level of knowledge about the contamination generated by the disposal of pharmaceutical waste.
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    Nivel de conocimiento sobre drogas de abuso (marihuana, cocaína y éxtasis) en estudiantes del 3° al 5° año de secundaria de la I.E. 6100 Santa Maria Reyna Quebrada Verde- Pachacamac. mayo-octubre 2019
    (Universidad Privada Norbert Wiener, 2020-08-27) Velarde Saccatoma, Maria Elena; Llahuilla Quea, José Antonio
    The present research aims to: Determine the level of knowledge about general concepts about drugs in the first measurement (Without talk), second measurement (With talk) and monitoring in students from 3rd to 5th year of secondary school at the I.E. 6100 Santa María Reyna– Quebrada Verde -Pachacamac -May – October 2019. Material and method: The research approach was quantitative. The design was analytical, observational, longitudinal with three measurements, initially the knowledge about drugs of abuse was measured, then a training was carried out, knowledge about drug abuse was measured again and subsequently a measurement was carried out to monitor knowledge about drug abuse. 53 students were selected. Results: In relation to the general concepts, the students without talk obtained (64.2% low level); with talk (39.6% regular level); monitoring (41.5% good level), a significant effect p <0.05 was found. Knowledge about cocaine, students obtained without talk (60% low level); with talk (45.3% regular level); monitoring (45.3% good level), a significant effect p<0.05 was found. Knowledge about marijuana the students obtained without talk (67.9% low level); with talk (52.8% regular level); monitoring (56.6% regular level), a significant effect p<0.05 was found. Knowledge about ecstasy the students obtained without talk (77.4% low level); with talk (50.9% good level); monitoring (43.4% regular level), a significant effect p<0.05 was found. Knowledge about the effects of drugs the students obtained without talk (58.5% low level); with talk (50.9% good level); monitoring (56.6% regular level), a significant effect p<0.05 was found. Knowledge about drug use the students without talk (60.4% low level); with talk (50.9% good level); monitoring (52.8% regular level), a significant effect p<0.05 was found. Conclusion: Knowledge about drug abuse (marijuana, cocaine and ecstasy in students without lecture (75.5% low level); with lecture (52.8% good level); monitoring (50.9% regular level), a significant effect was found p<0.05.
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