Tecnología Médica en Laboratorio Clínico y Anatomía Patológica
URI permanente para esta colecciónhttps://hdl.handle.net/20.500.13053/25
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Examinando Tecnología Médica en Laboratorio Clínico y Anatomía Patológica por Línea de Investigación "Salud y Bienestar"
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Ítem Acceso abierto Acute phase protein alterations in patients with a diagnosis of covid-19 in a polyclinic in Lima, 2020(Universidad Privada Norbert Wiener, 2023-09-24) Oliva Colan, Ana Rosa; Ascarza Gallegos, Justo AngeloCOVID-19 is a viral disease caused by SARS-CoV-2, which is distributed worldwide and causes high mortality and morbidity rates due to the acute inflammatory processes it induces. This study aims to determine the alterations of acute phase proteins in patients diagnosed with COVID-19 at a polyclinic in Lima, Peru, from April to September 2020. A descriptive cross-sectional study was conducted with 1,393 results, and a sample of 473 patients from the ROAL Polyclinic in Los Olivos district was analyzed. Serum concentrations of COVID-19 patients were evaluated using IgG, IgM, or both rapid tests. The analyzed acute phase proteins included C-reactive protein (CRP), lactate dehydrogenase (LDH), cortisol, and D-dimer. Data analysis and the construction of figures and tables were done using STATA v14.0, with statistical descriptive analysis for estimating frequencies and central tendency measures.Ítem Acceso abierto Alteration of biochemical markers in patients hospitalized for COVID-19 at the Suiza Lab private health institution from June 2020 to June 2021(Universidad Privada Norbert Wiener, 2023-06-25) Melgarejo Cobian, Melissa; Saldaña Orejón, Italo MoisésCOVID-19 is an infectious disease caused by the new coronavirus or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The severity levels of this disease have been described by the World Health Organization as mild, moderate, severe, and critical. To predict the progression of these severity levels, biomarkers have been used. These biomarkers are molecules that can be detected or quantified through laboratory tests.Ítem Acceso abierto Alteration of serum inflammatory markers according to the severity of Sars-Cov-2 infection in patients of the María Auxiliadora Departmental Support Hospital, Lima 2020.(Universidad Privada Norbert Wiener, 2022-06-25) Silva Delgado, Isabel; Astete Medrano, Delia JessicaThe present work is a descriptive cross-sectional study involving 349 patients treated at the Hospital de Apoyo Departamental María Auxiliadora. Patients of both genders, aged 18 to 96, with an inflammatory profile available (for PCR, LDH, ferritin, D-dimer, and Interleukin 6), and positive rapid or molecular tests for SARS-CoV-2, in mild, moderate, and severe stages, with a history of chronic diseases (diabetes mellitus and hypertension), were included. The main objective was to describe the alterations in serum inflammatory markers according to the severity of SARS-CoV-2 infection in patients at the Hospital de Apoyo Departamental María Auxiliadora, Lima, 2020. The conclusion was that serum inflammatory markers showed alterations with high values of interleukin, PCR, and D-dimer in patients with moderate and severe SARS-CoV-2 infection, while LDH and ferritin showed high values in mild, moderate, and severe stages in patients treated at the Hospital de Apoyo Departamental María Auxiliadora, Lima, 2020.Ítem Acceso abierto Anemia in pregnant women and hemoglobin in the Newborn Zapallal Maternal and Child Center march-april, 2022(Universidad Privada Norbert Wiener, 2022-12-04) Romero Ulloa De Eguizabal, Lucy; Astete Medrano, Delia JessicaThe WHO considers anemia with hemoglobin values below 11 g/dl for pregnant women. Globally, technical studies show that 52% of pregnant women in developing countries and 23% in developed countries have anemia. This project will be carried out at C.M.I. "DEMA-ZAPALLAL" from March to April 2022 to determine anemia in pregnant mothers and the hemoglobin levels of their newborns.Ítem Acceso abierto Associated factors and dermatophytes isolated in children aged 6-11 years with tinea capitis treated in a private laboratory, Lima 2024(Universidad Privada Norbert Wiener, 2024-07-20) Miranda Cardoza, Ana; Astete Medrano, Delia JessicaObjective: To determine the associated factors and the frequency of dermatophytes in children aged 6-11 years with tinea capitis treated at a private laboratory in Lima between January and March 2024. Materials and Methods: The study will use a deductive, non-experimental, and cross-sectional design to determine the relationship between the variables. The sample will consist of a total of 77 children aged 6-11 years with tinea capitis treated at a private laboratory in Lima between January and March 2024. Results: This research prioritized studying the frequency and relationship between dermatophytes and associated factors in children aged 6 to 11 years. The results showed that 39% of children had dermatophytes, with the presence of Trichophyton tonsurans (33.8%), Microsporum canis (3.9%), and Microsporum gypseum (1.3%). Conclusion: It was determined that there is no relationship between different demographic, socioeconomic, and environmental factors. The frequency of dermatophytes (p > 0.05) in children aged 6-11 years with tinea capitis treated at a private laboratory in Lima between January and March 2024.Ítem Acceso abierto Associated factors and frequency of toxoplasmosis in pregnant women treated at the National Teaching Hospital Mother-Child San Bartolomé, Lima, 2020-2022(Universidad Privada Norbert Wiener, 2023-11-26) Ubaldo Zavaleta, Eleana Liseth; Astete Medrano, Delia JessicaToxoplasmosis is a globally prevalent disease caused by the Toxoplasma gondii parasite, generally presenting as asymptomatic. This parasitic infection can be acquired in several ways, primarily orally, via oocysts excreted by cats, and through poorly washed meats.Ítem Acceso abierto Association between cardiovascular risk and erythrocyte distribution width in occupational patients of the Laura Caller Iberico-2023 Polyclinic(Universidad Privada Norbert Wiener, 2024-07-20) Huamani Paliza, Carolina Mirtha; Saldaña Orejón, Italo MoisésCardiovascular diseases (CVD) are a public health problem in Peru, with prevention being the primary strategy. Therefore, evaluating cardiovascular risk (CVR) in asymptomatic individuals who present risk factors is the main strategy. However, there is a need to identify new biomarkers that facilitate identification. RDW is known for its association with cardiovascular diseases, and research suggests a prognostic value for RDW. The objective was to investigate whether there is an association between cardiovascular risk and red cell distribution width (RDW) in occupational patients from the “Laura Calle Ibérico” polyclinic. Methods: The sample consisted of 201 occupational patients from the Laura Calle Ibérico polyclinic. The HEARTS application from PAHO was used to calculate CVR, and RDW, cholesterol, glucose, and other demographic data were collected on a data collection form. Results: No significant association was found between RDW and CVR (P=0.345), or between RDW, CVR, and cholesterol (P=0.97). However, an association was found between RDW, CVR, and age (P=0.000), RDW, CVR, and blood pressure (P=0.04), diabetes (P=0.00), and smoking habits (P=0.01). Furthermore, 23% of patients are at risk of developing cardiovascular issues within 10 years if corrective measures are not taken.Ítem Acceso abierto Association of serum cortisol levels and burnout syndrome in workers of the clinical pathology service of the Hospital Nacional Docente Madre Niño San Bartolomé, 2021(Universidad Privada Norbert Wiener, 2022-04-28) Bermudo Rodriguez, Juana Rosa; Valenzuela Martinez, Stefany SaragozaA descriptive cross-sectional study was conducted on 81 workers, including both male and female volunteers over 18 years old, medical laboratory technicians, clinical and pathological anatomy technologists, and pathologists. Cortisol concentration was measured, and the Maslach questionnaire was used to determine burnout syndrome. The participants had an average age of 42 ± 10.3 years (range 21 to 67 years), with 41 (50.6%) being female. The most frequent age groups were 31 to 40 years and 51 to 65 years, both accounting for 34.6%. Of the participants, 48 (59.3%) were medical technologists, 29 (35.8%) were laboratory technicians, and 3 (3.7%) were pathologists. The most common length of service was 1 to 10 years (43.2%), followed by 11 to 20 years (24.7%). Burnout syndrome was evident in 24 (29.6%), 64 (79%), and 72 (88.9%) participants in the emotional exhaustion, depersonalization, and personal accomplishment dimensions, respectively. A correlation was found between serum cortisol concentrations in the first morning analysis (A.M.) and all three burnout dimensions. Conclusion: There is an association between the first morning measurement of serum cortisol levels and all three dimensions of burnout syndrome.Ítem Acceso abierto Association of the neutrophil/lymphocyte index with the mortality of covid-19 patients at Hospital II Clínica Geriátrica San Isidro Labrador October 2020 – February 2021. Lima – Peru(Universidad Privada Norbert Wiener, 2023-11-19) Alcarraz Mondalgo, Katherine Ivonne; Huamán Cárdenas, Victor RaulThe neutrophil-lymphocyte index is a hematological marker previously studied for inflammation in various diseases. In COVID-19 infection, the NLR has gained significance for determining severity and predicting mortality in infected patients. This thesis seeks to associate the NLR with the mortality of COVID-19 patients at the San Isidro Labrador Geriatric Clinic, Lima, from October 2020 to February 2021. The study evaluated 180 patients diagnosed with COVID-19, using hematological values to determine the NLR and seek associations using SPSS. It found that 72.8% of deceased patients were male, with an average age of 76.1 years. The odds ratio was calculated, revealing that patients with an NLR >7 had a 9.7 times higher risk of death. The logistic regression analysis found that patients with elevated NLR had 1.5 times higher mortality risk (p: 0.000). It was concluded that NLR is a good predictor of mortality in COVID-19 infected patients.Ítem Acceso abierto Atypical findings in cervical cytology in patients treated at the Agusto Hernandez Mendoza Hospital in Ica, 2021(Universidad Privada Norbert Wiener, 2023-11-05) Díaz Palomino, Carlos Jesús; García Vásquez, Carlos HugoRecognizing the frequency of major abnormal findings will provide a theoretical basis for improving primary prevention for these patients through mass vaccination and raising awareness of the importance of proper gynecological check-ups to prevent cervical cancer. The center's preventive capacity will be enhanced by attracting more patients and performing cytologies according to the recommended guidelines, thereby reducing the number of cervical cancer cases diagnosed at advanced stages.Ítem Acceso abierto Bacterial agents in diabetic foot in the central laboratory of the María Auxiliadora departmental hospital, in Lima-Peru, period 2019(Universidad Privada Norbert Wiener, 2022-10-22) Chamana Quiroz, Jackelina María; Cabello Vílchez, Alfonso MartinAmong the microbiological agents that can cause infections in diabetic feet are those from the skin and intestinal flora. This study aimed to "Determine which bacterial agents are most predominant in diabetic feet isolated in the central laboratory of the María Auxiliadora Departmental Hospital in Lima, Peru, during the 2019 period." The methodology used was an observational, cross-sectional, and descriptive study. A total of 181 positive culture data with their respective susceptibility profiles were analyzed, concluding that the predominant bacterial agents were Gram-negative bacteria (63%), with the most frequent being Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, and Morganella morganii. The most sensitive drugs were Carbapenems, Amikacin, Vancomycin, and Teicoplanin, while the most resistant were Ampicillin, Cefuroxime, Penicillin, and Clindamycin.Ítem Acceso abierto Bacterial vaginosis and atypical squamous cells in cytological screening public health reference laboratory Sullana, 2019 - 2020(Universidad Privada Norbert Wiener, 2022-11-03) Sandoval Zapata, Jorge Luis; García Vásquez, Carlos HugoBacterial vaginosis (BV) is the most common vaginal infection worldwide, affecting the physical and emotional well-being of women and their intimate relationships with their partners. An increase in prevalence has been reported, especially in the northern regions of Peru, making it necessary to strengthen health services for timely detection and treatment. This correlational and descriptive research includes a population of 7,515 women of reproductive age, with a sample of 366 Papanicolaou smears from positive cervical samples. The objective is to identify the association between bacterial vaginosis and atypical squamous cells diagnosed through cytological screening in the Public Health Reference Laboratory of Sullana, 2019-2020. The study aims to detect vaginal infections like Gardnerella vaginalis and pre-malignant lesions like ASC-US and ASC-H, and establish the relationship between bacterial vaginosis and atypical squamous cells in the northern population of Peru, where local and regional studies on this issue are lacking. This could inform strategies for improving reproductive health education, communication, and services.Ítem Acceso abierto Beta vulgaris as a natural nuclear staining color for the histopathological diagnosis of breast cancer at V&M Clinic Image Medica S.A.C, Lima-Peru, 2023(Universidad Privada Norbert Wiener, 2023-11-26) Quispe Chancas, Nicol; García Vásquez, Carlos HugoBeta Vulgaris is a natural dye with tinting properties useful for staining histological tissues, which is particularly beneficial for histopathological diagnosis in one of the most common conditions among women in our country. The preparation and extraction of the dye are free from toxic substances.Ítem Acceso abierto Blood alcohol level and traffic accidents in drivers UNIDDE-PNP – Sede Sngamos 2020(Universidad Privada Norbert Wiener, 2022-04-28) Ninantay Vargas, Jackeline Ibeth; Ascarza Gallegos, Justo AngeloTraffic accidents are one of the national research priorities in Peru due to the number of lives lost daily. This situation worsens when the person (driver) has previously consumed alcoholic beverages, impairing reaction capacity, which often leads to fatal events. This study aims to understand whether there is a relationship between traffic accidents and blood alcohol levels in drivers examined at the UNIDDE-PNP, Angamos headquarters in 2020. A descriptive, retrospective, and cross-sectional study was conducted. The sample included 147 drivers who underwent an alcohol testing and had a positive result, and also participated in traffic accidents. The results from the alcohol testing certificates revealed that, according to the blood alcohol level, 52.4% (77) were in the drunken state, 34.7% (51) in absolute drunkenness, 10.9% (16) in subclinical state, and 2% (3) in severe alteration. According to age, the group aged 18-29 years had 40.1% (59), 30-40 years had 27.2% (40), 41-50 years had 23.9% (35), and 51-60 years had 8.8% (13). According to gender, 95.2% (140) were male and 4.8% (7) female. Regarding accident types, collision was 66.6% (98), skidding 23.8% (35), pedestrian hit 4.8% (7), and others (overturn and fire) 4.8% (7). Regarding vehicle type, 72.1% (106) were private vehicles, 17% (25) motorcycles, 5.5% (8) public transport, 3.4% (5) bicycles, and 2% (3) tricycles. Conclusion: No relationship was found between blood alcohol level and the type of traffic accidents.Ítem Acceso abierto Blood biometry and severity of covid-19 in adults over 60 years of age care at the HNAAA Essalud Chiclayo laboratory - january to april 2021(Universidad Privada Norbert Wiener, 2024-05-05) Aguilar Aguilar, Angélica María; Avelino Callupe, Paul FortunatoCurrently, a global challenge is being faced to overcome this health crisis, as since the outbreak of pneumonia of unknown causes was detected in the city of Wuhan, China, important studies have been conducted to provide knowledge and counteract this new virus, COVID-19. The factors predisposing patients to a severe state during COVID-19 include variables such as age (over 65 years), heart and vascular diseases, chronic kidney disease, chronic lung diseases, diabetes mellitus, obesity, neoplasms, immunosuppression, and pregnancy. The pandemic has caused high lethality in the Lambayeque region, overwhelming hospitals. Certainly, it is everyone's task to contribute to stopping the outbreaks that have emerged in such a short time; therefore, the general population is advised to follow all recommendations to prevent infection. Hematological testing is one of the most important laboratory tests, which through a complete blood count can identify imbalances in the patient's body and help determine the appropriate treatment. This research aims to relate hematological parameters and COVID-19 severity in people over 60 years old treated at the HNAAA Essalud Chiclayo laboratory from January to April 2021.Ítem Acceso abierto Burnout syndrome and associated factors in the care staff of the Synlab clinical laboratory - headquarters in the context of the Covid-19 pandemic. Lima, 2022(Universidad Privada Norbert Wiener, 2022-11-06) Aquino Fernandez, Anderson Felix; Tamayo Toro, Mónica AlexandraObjective: To identify the relationship between Burnout Syndrome (BOS) and associated factors in the laboratory staff at SYNLAB Central Headquarters during the COVID-19 pandemic in Lima, 2022. Materials and methods: A data collection form was used to gather information on biological, personal, work-related, and economic factors, and the Maslach Burnout Inventory - HSS was employed. Results: The found burnout level was medium (73.5%), followed by low and high levels (22.5% and 3.9%, respectively). The study population consisted of 74.5% females, with 50% in the 20-30 age group, and 66.7% expressed moderate satisfaction with their salary. A Spearman Rho of 0.875 with a p-value ≥0.05 indicated no correlation between the associated factors and BOS; however, a statistically significant relationship was found between BOS, age, and satisfaction with remuneration (p-values of 0.00 and 0.042, respectively). Conclusion: No correlation was found between associated factors and burnout syndrome, but there was a statistically significant relationship between BOS, age, and satisfaction with salary.Ítem Acceso abierto C-Reactive Protein and Its Relationship with Risk Factors Associated with Metabolic Syndrome in Maintenance Workers Assisted for an Occupational Health Evaluation in 2016(Universidad Privada Norbert Wiener, 2017-11-10) Vásquez Mosanapón, Juana Iris; Benites Azabache, Juan CarlosObjective: To establish the relationship between C-reactive protein (CRP) levels and risk factors associated with metabolic syndrome in maintenance workers undergoing Occupational Health assessments in 2016. The study type was quantitative, prospective, cross-sectional, descriptive. Maintenance workers who underwent annual health checks at an occupational health laboratory in 2016 were tested for glucose, HDL cholesterol, triglycerides, and measurements of waist circumference and blood pressure. These results were compared with CRP levels. Regarding the Spearman correlations between CRP and factors associated with metabolic syndrome, a correlation coefficient of 0.190 was observed with a significance of 0.086, indicating no significant relationship with CRP. However, a significant relationship was found between glucose and CRP in this population, with a correlation coefficient of 0.291 and a significance of 0.008. Among the metabolic syndrome factors compared with CRP, glucose was found to have a significant relationship with a correlation coefficient of 0.291 and significance of 0.008.Ítem Acceso abierto Causal factors of rejection in blood donors treated at the Huacho Regional Hospital, in the months of January to June 2019(Universidad Privada Norbert Wiener, 2023-08-20) Huertas Alva, Katherine Rossmary; Champa Guevara, Cesar AlfonsoBlood transfusion is a vital component of modern healthcare that saves millions of lives annually. It is essential to ensure that donors are free of HIV, hepatitis, and other infections potentially transmitted through unsafe transfusions. Rejection factors in blood donors include physical, sociocultural, and risk factors.Ítem Acceso abierto Cellular descriptors and cytologic malignancy criteria using digital imaging in blood-infiltrating lymphomas in a private institution - 2021(Universidad Privada Norbert Wiener, 2022-03-31) Vasquez Huete, Abigail Eunice; Avelino Callupe, Paul FortunatoScientific research consists of relating the cellular descriptors and the criteria of cytological malignancy with the purpose of contributing to the support of the diagnosis of malignant neoplasms in an objective manner where each region of cellular interest is quantified that allows differentiating various types of lymphoma cells that infiltrate peripheral blood, from digital images classified by the expert as cells belonging to a lymphoma, leading to determining a relationship between the objective value (descriptors) versus the subjective values (malignancy criteria).Ítem Acceso abierto Cellular descriptors in plasmacytes of bone marrow smears from patients with hematological neoplasia in the INEN – 2021(Universidad Privada Norbert Wiener, 2023-06-25) De La Cruz Solier, Ivonne Mercedes; Avelino Callupe, Paul FortunatoCellular descriptors change the perspective of a hematology laboratory, enabling significant technological advances, ease of cellular recognition, and a larger morphological database. They also facilitate the reading of qualitative data by transforming it into quantitative, thus avoiding subjectivity between operators. This improves quality, time, and costs, offering a better outlook with enhanced education and training. The objective of this study is to analyze cellular descriptors in plasmacytes from bone marrow smears of patients with hematologic neoplasms at INEN in 2021. This study focuses on hematologic neoplasms, particularly plasma cell neoplasms, where plasmocytes proliferate and migrate to peripheral blood in advanced stages of the disease. Proper diagnosis in bone marrow smears is critical for timely intervention. Using our image database and cellular descriptors, plasmocytes will be described geometrically and colorimetrically.