Examinando por Materia "Clorhexidina"

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(Universidad Privada Norbert Wiener, 2015) Juscamaita Gutierrez, Elizabeth Stefany; Malpartida Quispe, Federico Martin
The objective of this study was to determine the inhibitory effect of the essential oil of Eucalyptus globulus compared to 0.12% Chlorhexidine Gluconate and Colgate Plax® mouthwash on the bacterial inhibition of Streptococcus mutans. The study was experimental, cross-sectional, prospective, and analytical, with an explanatory level, conducted in a laboratory. The population consisted of Streptococcus mutans (ATCC 25175) strains, and the sample included 40 Petri dishes. The culture medium used was Blood Agar, and 6 mm diameter wells were made in each Petri dish using a sterile punch. The essential oil of Eucalyptus globulus at concentrations of 25%, 50%, and 100%, 0.12% Chlorhexidine Gluconate, Colgate Plax® mouthwash, and Tween 20 were added to the wells. The results showed that the 25%, 50%, and 100% concentrations of Eucalyptus globulus essential oil produced inhibition halos with average diameters of 6.88 mm, 9.61 mm, and 12.65 mm at 24 hours, and 6.88 mm, 9.53 mm, and 11.90 mm at 48 hours, respectively, which were smaller than the inhibition halos produced by 0.12% Chlorhexidine Gluconate and Colgate Plax® mouthwash at both 24 and 48 hours against the Streptococcus mutans (ATCC 25175) strain.
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(Universidad Privada Norbert Wiener, 2017-11-20) Cueva Rosales, Javier; Pareja Cuadros, Elizabeth Irene
The purpose of this research was to assess the antimicrobial activity of rosemary essential oil (Rosmarinus officinalis) against the growth of Streptococcus mutans ATCC 25175 "in vitro". For the microbiological analysis, 100% rosemary essential oil was used and the agar well diffusion method was applied. Thirty Petri dishes with Muller Hinton agar were prepared, each containing a 6 mm diameter well saturated with rosemary essential oil and 0.12% chlorhexidine (DENTODEX®). The samples were incubated at 37°C and were only removed to measure and record the bacterial inhibition halos after 72 and 168 hours. The essential oil was compared with 0.12% chlorhexidine gluconate as a positive control for Streptococcus mutans ATCC 25175, and sterile distilled water was used as the negative control. The data were processed using SPSS, and the T-test was applied. The study concluded that Rosmarinus officinalis (rosemary) essential oil exhibited "in vitro" antibacterial activity against Streptococcus mutans ATCC 25175 at 72 hours, and 0.12% chlorhexidine showed greater antibacterial activity than the essential oil against this bacterial strain at 168 hours.
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(Universidad Privada Norbert Wiener, 2018-04-04) Luis Barrientos, Angel Jorge; Pareja Cuadros, Elizabeth Irene
The objective of this research was to assess the antibacterial activity of the essential oil of Cinnamomum zeylanicum (cinnamon) compared to 0.12% chlorhexidine against Streptococcus mutans ATCC 25175 "in vitro". The study was experimental, prospective, and longitudinal. The essential oil was obtained using the steam distillation method from the bark of Cinnamomum zeylanicum (cinnamon). For microbiological analysis, the essential oil was used at 100%, and the well-agar diffusion method was applied. Thirty Petri dishes with Muller Hinton agar were prepared, each with a 6 mm diameter well saturated with cinnamon essential oil and 0.12% chlorhexidine (DENTODEX®). The samples were incubated at 37°C, and inhibition zones were measured and recorded at 72 and 120 hours. The essential oil was compared to 0.12% chlorhexidine as a positive control for Streptococcus mutans ATCC 25175, with sterile distilled water as the negative control. The data were processed using SPSS, and the T-Student statistical test was applied. The study concluded that the essential oil of Cinnamomum zeylanicum (cinnamon) showed stability and antibacterial activity "in vitro" against Streptococcus mutans ATCC 25175 at 72 and 120 hours. Chlorhexidine 0.12% showed greater antibacterial activity than the essential oil at 120 hours.
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(Universidad Privada Norbert Wiener, 2017) Quichca Mendoza, Juán Carlos; Aguirre Morales, Anita Kori
Throughout history, periodontal disease has been present, with multiple treatments using natural derivatives to address this condition. Therefore, the objective of this in vitro study was to determine the efficacy of Minthostachys mollis (muña) essential oil and 0.12% Chlorhexidine in inhibiting the growth of Porphyromonas gingivalis. The sample consisted of 40 Petri dishes inoculated with Porphyromonas gingivalis strains, and the agar diffusion method using paper discs was employed. The discs were impregnated with 20 µl of 50% and 100% Minthostachys mollis (muña) essential oil, 0.12% Chlorhexidine, and distilled water. The Petri dishes, inoculated and medicated, were incubated for 24 hours at 37°C and were removed only to measure the inhibition halos at 24 and 48 hours. The data were processed using analysis of variance (ANOVA). Conclusion: The essential oil of Minthostachys mollis (muña) at 50% and 100% were less effective than 0.12% Chlorhexidine in inhibiting the growth of Porphyromonas gingivalis at both 24 and 48 hours.
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(Universidad Privada Norbert Wiener, 2015) Cerga Rodriguez, Leslie Alexandra; Malpartida Quispe, Federico Martin
The objective of this study was to determine the inhibitory effect of essential oils from Cinnamomum zeylanicum (cinnamon) and Syzygium aromaticum (clove) in comparison to 2% Chlorhexidine Gluconate against Enterococcus faecalis strains. The study was experimental, prospective, longitudinal, and analytical. The essential oils from these plants were obtained using the steam distillation method, utilizing the bark of Cinnamomum zeylanicum (cinnamon) and dried buds of Syzygium aromaticum (clove) at concentrations of 1%, 5%, 25%, 50%, 75%, and 100%. For the experiment, Enterococcus faecalis (ATCC 29212) was reactivated and then cultured on Petri dishes (15 cm in diameter) containing Mueller Hinton agar with 6 mm diameter wells, where approximately 100 µl of the essential oils were added, compared to 2% Chlorhexidine Gluconate as a positive control and Tween 20 as a negative control. The plates were incubated at 37°C to check for bacterial viability and media sterility, and the inhibition zones were measured using a Vernier caliper at 24 and 48 hours. In vitro sensitivity testing yielded the following results: the antimicrobial effect of Cinnamomum zeylanicum (cinnamon) essential oil at its minimum effective concentration (1%) was greater than the antimicrobial effect of Syzygium aromaticum (clove) essential oil at its minimum effective concentration (25%). Additionally, a greater antimicrobial effect was observed with the positive control, 2% Chlorhexidine Gluconate.
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(Universidad Privada Norbert Wiener, 2015) Carhuaricra Soto, Yudiht Abigail; Malpartida Quispe, Federico Martin
In periodontal disease, various microorganisms are involved, one of which is Porphyromonas gingivalis, an obligate anaerobic, Gram-negative bacterium that is predominantly found in chronic periodontitis, and is commonly eliminated by 0.12% chlorhexidine. The purpose of this study was to determine the inhibitory effect of Rosmarinus officinalis (rosemary) essential oil and 0.12% chlorhexidine on Porphyromonas gingivalis, using the agar diffusion method with discs, as an effort to find an alternative, natural, effective, and economical antimicrobial substance against this bacterium. For this, Porphyromonas gingivalis strains were inoculated in 40 Petri dishes containing Mueller Hinton agar. Then, three discs were placed on each plate, impregnated with 20 µl of 0.12% chlorhexidine, Rosmarinus officinalis essential oil, and distilled water as a negative control. The plates were incubated at 37°C in an anaerobic jar for the duration of the study, being removed only to measure the inhibition halos generated at 24 and 48 hours. The data were processed using SPSS software, and the Student's T-test was applied. It was concluded that Rosmarinus officinalis (rosemary) essential oil exhibited an inhibitory effect against Porphyromonas gingivalis, and 0.12% chlorhexidine had a greater inhibitory effect than the essential oil against this bacterial strain.
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(Universidad Privada Norbert Wiener, 2015) Trauco Villavicencio, Sandra Lizzeth; Galvez Ramirez, Carlos Michell
The objective of this study was to determine the efficacy of 0.12% Chlorhexidine and 0.1% and 0.2% Sodium Hypochlorite for controlling the most prevalent bacterial contamination on toothbrushes used by 7-year-old schoolchildren at the Parroquial Nuestra Señora de Montserrat Educational Institution. To this end, the toothbrushes used by the schoolchildren for a period of 47 days were collected in sterile urocultivation containers containing 5 ml of sterile TSB broth and incubated at 35°C for 18 hours. Then, 1 μl (0.001 ml) of the broth was streaked and diluted on MacConkey agar plates, which were incubated at 35°C for 18 hours. The reading was based on colonial characteristics, followed by microorganism identification. The antibacterial substances in Mueller Hinton plates were incubated for 24 hours at 35°C, after which the inhibition zones were measured with a Vernier caliper or ruler. The results showed that the most prevalent microorganisms on the toothbrushes used by the schoolchildren were Pseudomonas spp. (28.3%) and Pseudomonas aeruginosa (6.5%) on non-contaminated plates, while on contaminated plates, Pseudomonas spp. accounted for 65% and Pseudomonas aeruginosa for 15%. The antibacterial efficacy identified that 0.12% Chlorhexidine had a greater inhibitory effect for controlling bacterial contamination found on the toothbrushes compared to 0.1% and 0.2% Sodium Hypochlorite. It was concluded that the most prevalent bacteria were more resistant to the inhibitory effect of 0.1% and 0.2% Sodium Hypochlorite.
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(Universidad Privada Norbert Wiener, 2015) Atencio Chauca, Evelyn Karin; Cupé Araujo, Ana Cecilia
The objective of this study was to determine the inhibitory effect of Vaccinium corymbosum (Blueberry) at 100%, 75%, 50%, 25%, and 0.12% Chlorhexidine Gluconate against the presence of Streptococcus mutans in an in vitro study in Lima, 2015, at 24 and 48 hours. To this end, Streptococcus mutans strains were isolated from saliva collected from a patient and cultured on Petri dishes containing Blood Agar medium, with 6 mm diameter wells where approximately 100 µl of the 100%, 75%, 50%, 25% extracts, 0.12% Chlorhexidine Gluconate, and distilled water were poured. The plates were incubated at 37°C, including two control plates to check the viability of the bacteria and the sterility of the medium. After incubation, the inhibition halos were measured with a Vernier caliper or ruler at 24 and 48 hours. For data analysis, ANOVA and Dunnett tests were used, showing that 0.12% Chlorhexidine Gluconate had a significantly higher inhibitory effect than the 100% Vaccinium Corymbosum extract (P<0.05), and the 75% and 50% Vaccinium Corymbosum extracts (P<0.05). It was concluded that the inhibitory effect of 100% Vaccinium Corymbosum is lower than that of 75% Vaccinium Corymbosum and very similar to 0.12% Chlorhexidine Gluconate in the bacterial culture of Streptococcus mutans at 24 and 72 hours.
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(Universidad Privada Norbert Wiener, 2014) Zavala Vega, Luis Antonio; Malpartida Quispe, Federico Martin
The presence of bacteria in the root canal induces chronic periapical disease. Therefore, one of the most important objectives of endodontic treatment is to eliminate all microorganisms from the root canals, using both irrigating solutions and intra-canal medication between sessions, especially in cases of endodontic retreatment, due to the presence of persistent bacteria that may resist various commonly used intra-canal medications. Enterococcus faecalis are the most frequently isolated bacteria from teeth with endodontic failure and the main contributors to persistent apical periodontitis. The objective of this study was to evaluate the inhibitory effect of 2% chlorhexidine gel and calcium hydroxide mixed with various vehicles (2% chlorhexidine solution, camphorated paramonochlorophenol, and saline solution) against Enterococcus faecalis, using the agar well diffusion method. Fifty Petri dishes with brain heart agar were prepared, with each dish containing 4 wells saturated with intra-canal medications. The samples were incubated at 37°C, and measurements of bacterial inhibition zones were recorded at 1, 7, and 15 days. The data were processed using the analysis of variance statistical test, concluding that 2% chlorhexidine gel has greater antibacterial efficacy than calcium hydroxide combined with various vehicles (2% chlorhexidine solution, camphorated paramonochlorophenol, and saline solution) after 1, 7, and 15 days against Enterococcus faecalis.
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Acción antibacteriana del extracto etanólico de Azadirachta Indica (Neem) en comparación con el Gluconato de Clorhexidina al 0.12% con Cloruro de Cetilpiridinio 0,05% frente a las cepas de Porphyromonas gingivalis. Estudio in vitro. Lima. 2023
(Universidad Privada Norbert Wiener, 2024-10-04) Rosas Benites, Viviangelli Vanessa; Morante Maturana, Sara Angélica
Con el propósito de aportar un enfoque terapéutico diferente y natural, se efectuó una investigación en la que se evaluó dicha diferencia en la acción antibacteriana in vitro entre el extracto etanólico del Azadirachta indica comparado con la clorhexidina al 0,12% con CPC al 0,05% sobre las cepas de Porphyromonas gingivalis. Cabe resaltar que la muestra estuvo conformada por 15 de muestra por sustancia de prueba; fraccionadas en grupos: tres grupos con el extracto etanólico al 25%, 75% y 100% y dos grupos con los respectivos controles tanto positivo como negativo que, en total se emplearon 75 placas de agar Schaedler enriquecido Es una investigación hipotética/ deductivo, desde un enfoque cuantitativo, de tipo aplicada, diseño experimental in vitro. Los resultados demostraron que existe acción antibacteriana significativo en relación con la medida de Duraffourd. Tratándose en el caso de la clorhexidina al 0,12% y CPC al 0,05% los valores medios después de transcurridas 24 h (14,34 mm), 48 h (14,22 mm) y 72 h (14,11mm); en cuanto al extracto etanólico al 100% presentó promedios, a las 24 h (11,38 mm), 48 h (11,27 mm) y 72 horas (11,15 mm); el extracto etanólico al 75% registró valores estadísticos, en 24 h (9,19 mm), 48 h (9,08 mm) y 72 h (8.97 mm); a la vez el extracto etanólico al 25% no presentó acción antibacteriana. Se llegó a la conclusión, que el gluconato de clorhexidina al 0,12% y CPC al 0,05% presenta mayor actividad antibacteriana en contraste con los extractos etanólicos en estudio.
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Antibacterial activity of eucalyptus globulus essential oil compared to 0.12% chlorhexidine gluconate in inhibiting porphyromona gingivalis in vitro.
(Universidad Privada Norbert Wiener, 2021-05-05) Feldmuth Gonzales, Henry Jefferson; Girano Castaños, Jorge Alberto
Objective: The objective of this research was to determine the antibacterial activity of eucalyptus essential oil (Eucalyptus globulus) compared to 0.12% chlorhexidine digluconate in inhibiting Porphyromonas gingivalis in vitro. Methodology: A quasi-experimental design was developed, considering the antibacterial agent variable in 4 concentrations of eucalyptus essential oil (10%, 25%, 50%, 100%) and 0.12% chlorhexidine digluconate. Porphyromonas gingivalis bacteria were cultured in media using a sample of 40 plates. Results: This research found that Eucalyptus globulus exhibited greater antibacterial activity at all concentrations than 0.12% chlorhexidine, both at 24 and 48 hours against Porphyromonas gingivalis. The smallest inhibition halo was found for 10% eucalyptus with 18.65 mm, and the largest was for 100% eucalyptus at 48 hours with 29.55 mm. Conclusion: Eucalyptus essential oil (Eucalyptus globulus) has significantly greater antibacterial activity than 0.12% chlorhexidine digluconate in inhibiting Porphyromonas gingivalis in vitro.
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Antibacterial effect of ethanolic extract of propolis at 30% and cetylpyridinium chloride at 0.05% plus chlorhexidine digluconate at 0.05% on strains of Streptococcus mutans (ATCC 25175). In Vitro comparative study. 2021.
(Universidad Privada Norbert Wiener, 2022-02-10) Ochoa Concha, Rubila Celeste; Schwan Silva, Ignacio Segundo
This is an in vitro experimental study using two samples: Sample 1, 30% ethanol propolis extract, and Sample 2, cetylpyridinium chloride at 0.05% plus chlorhexidine digluconate at 0.05%, with chlorhexidine digluconate at 0.12% as the control group. Inhibition halos were measured around each of the discs soaked with the antibacterial substances placed on the plates. The plates were incubated for 48 hours, and the halos were measured using a Vernier caliper. The Duraffourd et al. scale (1986) was used for interpreting the antibacterial effect against Streptococcus mutans. The streaking and exhaustion technique was used on the agar. A total of 30 experimental units were plated on blood agar, on which 3 sterile antibiogram discs of 6mm each were placed, inoculated with Streptococcus mutans.
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Comparison of the antibacterial effectiveness of irrigants based on 0.12% chlorhexidine and ozonized sunflower oil on porphyromonas gingivalis strains - in vitro study, Lima - 2023
(Universidad Privada Norbert Wiener, 2023-06-08) Blas Huaroc, Esteban Abraham; Huayllas Paredes, Betzabé
The objective was to determine the antibacterial effectiveness of irrigants based on 0.12% Chlorhexidine and ozonized sunflower oil against Porphyromonas gingivalis strains. This was an applied research study with an analytical method, quantitative focus, and an in-vitro experimental design, where microorganisms were cultured on 40 Petri dishes containing agar. The results showed significant antibacterial effects of both 0.12% Chlorhexidine and ozonized sunflower oil, according to the Duraffourd Scale. Chlorhexidine 0.12% showed average inhibition zones of 17.58 mm at 24 hours, 17.56 mm at 48 hours, and 17.55 mm at 72 hours. On the other hand, ozonized sunflower oil showed inhibition zones of 36.5 mm at 24 hours, 36.49 mm at 48 hours, and 36.47 mm at 72 hours. It was concluded that ozonized sunflower oil had a better antibacterial effect than 0.12% Chlorhexidine against Porphyromonas gingivalis strains.
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Determination of the appropriate concentration for oral hygiene with Chlorhexidine in the prevention of pneumonia in intubated patients in the intensive care unit
(Universidad Privada Norbert Wiener, 1905-07-09) Chavalía Cóello, Diana Elizabeth; Menacho Vergara, Lissette Carolina; Gómez Gonzales, Walter Edgar
Objective: Determine the best concentration of chlorhexidine used to perform oral hygiene to prevent pneumonia in intubated patients. Materials and Methods: Systematic reviews are an observational and meta-analysis research design, which synthesizes the results of multiple primary investigations. They are an essential part of evidence-based nursing due to their rigorous methodology, which is why a systematic review was carried out with articles in English and Spanish indexed in Cochrane, Embase, Lilacs, Pubmed, Medline, identifying relevant studies to answer specific questions of clinical practice. Results: The SCHEFFE statistical test indicated that of oral hygiene, chlorhexidine showed a statistically significant difference over other forms of hygiene in the reduction of the number of bacterial colonies (p<0.001). The only effect on reducing VAP was found when 0.12% chlorhexidine was used, used in cardiovascular surgery, where Chlorhexidine is used from preoperatively. Conclusions: Oral care, cleaning and antisepsis is a useful strategy for the prevention of pneumonia associated with intubated patients; It was also determined that 0.12% chlorhexidine was effective in reducing colonization of the oropharynx and the incidence of pneumonia associated with intubated patients.
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Efectividad antimicrobiana de la clorhexidina al 2% e hipoclorito de sodio al 2,5% y 5% frente a una bacteria (Enterococcus faecalis) y un hongo (Candida albicans) Estudio in vitro, Lima 2024
(Universidad Privada Norbert Wiener, 2025-06-30) Huaman Pineda, Eva; Torres Pariona, David Arturo
El presente estudio planteó como objetivo determinar la efectividad antimicrobiana de la clorhexidina al 2% e hipoclorito de sodio al 2.5% y 5% frente a una bacteria (Enterococcus faecalis) y un hongo (Candida Albicans). Es un estudio de método hipotético deductivo, cuantitativo de tipo aplicada y diseño experimental. Se activaron y replicaron las especies microbianas: bacteria Enterococcus faecalis (cepa ATCC 29212) y el hongo Candida albicans (cepa ATCC 90028). Para ello, se emplearon 30 placas de Petri (15 para cada microorganismo) con cultivos estandarizados, las cuales se incubaron a 37°C en condiciones controladas. Una vez sembradas las cepas bacterianes se produjeron 4 pozos de 6 mm de diámetro equidistantes en cada placa Petri, en los cuales se agregó 25 μL de cada sustancia y dejada por un plazo de 72 horas a una temperatura de 37°, siendo únicamente evaluados la efectividad antimicrobiana en el transcurso de las 24, 48 y 72 horas. La mayor efectividad antimicrobiana la presento la clorhexidina solución al 2%, seguido de la clorhexidina gel al 2%, hipoclorito de sodio al 5% e hipoclorito de sodio al 2.5%. Se concluye que la clorhexidina al 2% presento mayor efectividad antimicrobiana frente a una bacteria (Enterococcus faecalis) y un hongo (Candida albicans).
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EFECTIVIDAD DEL USO DE CLORHEXIDINA EN LA PREVENCIÓN DE ONFALITIS EN NEONATOS
(Universidad Privada Norbert Wiener, 2018-08-26) Egoavil Churampi, Keyla Fiorella; Bonilla Asalde, Cesar Antonio
Objetivo: Sistematizar las evidencias sobre la efectividad del uso de clorhexidina en la prevención de onfalitis en neonatos. Material y Métodos: Estudio de enfoque cuantitativo, el diseño de investigación utilizado fue una revisión sistemática. La Población incluyo 74 artículos, la muestra fue 10 artículos científicos. Se consultaron las siguientes bases de datos: Wolters Kluwers, Pubmed, Wiley One Library, Cochrane, Data base. Los artículos seleccionados fueron sujetos a selección critica, usando el sistema de evaluación Grade para la identificación del grado de evidencia. La calidad de la evidencia se encontró alta en un 100% de estudios revisados, los cuales proceden de la India 30%, Estados Unidos 30%, Kenia 10%, Países Bajos 10%, Pakistán 10% y África 10%. Los 10 artículos revisados sistemáticamente por su diseño se distribuyeron de la siguiente manera: el 40% (n= 4/10) son revisiones sistemáticas, 10% (n= 4/10) meta análisis, y el 50% (n= 5/10) fueron ensayos clínicos controlados. Resultados: La revisión sistemática demostró el 100% de los artículos analizados que el uso de la clorhexidina es efectivo para la prevención de onfalitis en neonatos. Conclusión: Se encontró la efectividad del uso de clorhexidina en la prevención de onfalitis en neonatos.
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Effective interventions for the prevention and management of oral mucositis in cancer patients
(Universidad Privada Norbert Wiener, 1905-07-09) Pajuelo Coronel, Carmen Guadalupe; Pizarro Paucar, Maribel Felicitas; Mendigure Fernández, Julio
100% of the studies included in the systematic review show that effective interventions for prevention are: Systematic oral hygiene, amifostine, antibiotic tablet or paste, ice tablets, zinc supplements, bicarbonate rinses sodium, cryotherapy, plantain rinses, chlorhexidine rinses, and laser therapy; and for treatment they are: hydrolytic enzymes, morphine rinses, sodium bicarbonate rinses, zinc supplements, cryotherapy, chlorhexidine rinses and the topical application of pure honey.
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Effective nursing interventions for the prevention of pneumonia associated with mechanical ventilation
(Universidad Privada Norbert Wiener, 1905-07-09) Cusi Delgado, Libia; Solis Ramos, Melody; Bonilla Asalde, César Antonio
Objective:Analyze the evidence on effective nursing interventions for the prevention of pneumonia associated with mechanical ventilation.Methodology:The search was carried out in the Pubmed, Cochrane, Elsevier, Lilacs, Scielo and Google Scholar database of articles published between 2012 and 2017 whose main theme is effective nursing interventions in the prevention of pneumonia associated with mechanical ventilation. Results: Of 10 scientific reviews, 100% are of quality high, of the total of systematic reviews, 6 articles conclude that oral hygiene with chlorhexidine reduces the incidence of pneumonia associated with mechanical ventilation, 4 articles conclude that elevation of the head of 30|-60° reduces the incidence of pneumonia associated with mechanical ventilation. mechanical ventilation, 3 articles conclude that aspiration and management of secretions reduces pneumonia associated with mechanical ventilation and 1 article concludes that abdominal massage and post-pyloric feeding reduce the risk of pneumonia associated with ventilation. mechanics.Conclusion:Effective nursing interventions for the prevention of pneumonia associated with mechanical ventilation include oral cavity hygiene with chlorhexidine, elevation of the head of the head 30°-60°, aspiration and management of secretions, post-pyloric feeding and the abdominal massage.
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Effectiveness of 2% chlorhexidine gluconate for central venous catheter care to reduce infections in ICU patients
(Universidad Privada Norbert Wiener, 2020-01-19) Becerra Camarena, Milagros Maria; Castillo Avalos, Geisy Evelin; Cárdenas de Fernández, María Hilda
Objective: Analyze and Systematize the evidence on the effectiveness of the use of chlorhexidine gluconate in healing to reduce infections associated with central venous catheters in ICU patients Methodology: Systematic review is a compilation of quantitative and qualitative aspects of articles, with the purpose to synthesize information from multiple investigations regarding the specific topic; Likewise, its use is essential for evidence-based nursing practice and an essential instrument for determination. However, obtaining quality systematic reviews is not an easy task. A sample of 10 articles was considered, which were studied using the GRADE scale. Results: 50% of studies affirm that CHG is more effective in reducing infections associated with the central venous catheter; However, 50% assure that there is no significant discrepancy with other antiseptics. Conclusion: In the studies evaluated, it is found that CHG is more effective in curing to reduce infections associated with CVC, however there are other measures that help avoid STIs such as hand washing, use of biosafety barriers, among others.
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Effectiveness of chlorhexidine in preventing infections associated with the insertion of the hemodialysis catheter.
(Universidad Privada Norbert Wiener, 2017-07-22) Mendoza García, Dianith Albina; Gómez Gonzales, Walter Edgar
Objective: This is a systematic review that included 10 articles, no older than 10 years, published in English, Portuguese, and Spanish, in the following databases: Pubmed, Scielo, Journal Medical, Lilacs, and Bvs. The main topic was the effectiveness of chlorhexidine in preventing infections associated with the insertion and use of hemodialysis catheters. 80% of the articles are from Spain, 15% from Chile and Brazil, and 5% from Valencia, respectively. Results: 100% of the selected articles demonstrate the positive effect of chlorhexidine in preventing infections associated with the insertion and use of hemodialysis catheters. 70% of the articles showed that chlorhexidine is effective in reducing bacteremia, 20% emphasized the importance of applying a set of biosafety measures to prevent infections related to central venous catheters in this patient population, and 10% focused on the application of protocols for the management of hemodialysis catheters. Conclusion: The evidence demonstrates that chlorhexidine improves the quality of life for individuals undergoing hemodialysis, as it has a positive impact on preventing bacteremia-related infections associated with hemodialysis catheters.