Examinando por Autor "Félix Véliz, Luis Miguel Visitación"

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Actitud de las personas con afecciones gastrointestinales en el uso de plantas medicinales como terapia alternativa que acuden al mercado Real Plaza Vitarte APROMEC – Ate, 2023
(Universidad Privada Norbert Wiener, 2023-09-22) Barzola Lopez, Ricardo Jack; Lovera Llamoja, Roxana Patricia; Félix Véliz, Luis Miguel Visitación
The objective of this research was to “Determine the attitude of individuals with gastrointestinal conditions towards the use of medicinal plants as an alternative therapy.” The methodology was based on a deductive method with a quantitative approach, basic type, descriptive level, non-experimental design, and cross-sectional approach. The sample consisted of 267 people. A survey and a questionnaire were used as the technique and instrument, respectively. The data obtained were entered and processed using Excel and SPSS software, achieving a good reliability score of 0.810. The results showed that 77.9% of the respondents were between the ages of 31 and 59 years, 73.4% were female, and 60.3% had secondary education. The most consumed plants were chamomile (26.97%), followed by muña (19.10%), mint (13.11%), and lemongrass (11.61%). Regarding attitudes, 89.5% of the participants exhibited a positive attitude, and 10.5% had a neutral attitude. Conclusion: It was determined that individuals with gastrointestinal conditions who use medicinal plants as an alternative treatment have a positive attitude. Additionally, the various dimensions analyzed showed positive results, except for the dimensions of safety and efficacy, where the attitude was neutral.
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Actividad antibacteriana de los extractos de acetato de etilo y acetona del zumo de Punica granatum L. "granada"
(Universidad Privada Norbert Wiener, 2017-11-13) Escobar Figueroa, Bernardita Jaquely; Quispe Quispe, Lidia; Félix Véliz, Luis Miguel Visitación
Punica granatum L. (“pomegranate”) has been used in traditional medicine since ancient times for the treatment of various diseases. Several studies have demonstrated its antioxidant, anti-inflammatory, antiparasitic, and antifungal properties, mainly from hydroalcoholic extracts of the peel. However, few studies have investigated pomegranate juice extracts using acetone and ethyl acetate. The aim of this research was to evaluate the antibacterial activity of acetone and ethyl acetate extracts from pomegranate juice. Antibacterial activity was assessed using the disk diffusion method. Four concentrations (200 mg/mL, 300 mg/mL, 400 mg/mL, and 500 mg/mL) of each extract were tested against Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Pseudomonas aeruginosa ATCC 27853. Inhibition zones were qualitatively determined according to the Durafford scale for in vitro inhibitory effects in phytotherapy and CLSI antimicrobial standards. The results indicated that the acetone extract exhibited antibacterial activity against S. aureus and E. coli. Furthermore, a comparative analysis revealed that microbial inhibition was inversely proportional to the quantification of ellagic acid. These findings highlight the potential of pomegranate juice acetone extract as a natural antimicrobial source.
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Actividad antibacteriana de los extractos hidroalcohólicos de las hojas, flores, tallo y raíz de Schkuhria pinnata (Lanm.) Kuntze ex Thell. “canchalagua” frente a Propionibacterium acnes
(Universidad Privada Norbert Wiener, 2018-03-13) Purizaca Meléndez, Kevin Manuel Eduardo; Condori Antialon, Laura Isabel; Félix Véliz, Luis Miguel Visitación
The plant species Schkuhria pinnata (Lanm.) Kuntze ex Thell, “Canchalagua,” from the city of Ayacucho, was obtained at the Wholesale Market “La Parada,” district of La Victoria – Lima, and was subsequently taxonomically classified at the Natural History Museum of the Universidad de San Marcos. The sample was cleaned and dried at the Research Center of the Universidad Norbert Wiener, where the parts of the plant—stem, root, leaves, and flowers—were separated. Hydroalcoholic extracts of each part were prepared, and the phytoconstituents present were identified, such as flavonoids, reducing sugars, phenolic compounds, and carbohydrates. For the microbiological test, the Disk Diffusion method was used with blood agar medium and the Propionibacterium acnes strain (ATCC® 11827). Standard antibiotics Q.P.: Doxycycline, Levofloxacin, Azithromycin, and Penicillin were employed. Disks impregnated with 10 µL of the hydroalcoholic extracts were added and compared with the standard antibiotic disks on the plates, showing that the hydroalcoholic extract of the leaves presented the largest inhibition halo diameter.
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Actividad antibacteriana frente a Cutibacterium acnes y antioxidante de los extractos hidroalcohólicos de las hojas, flores, tallo y raíz de Hypericum silenoides Juss "canchalagua"
(Universidad Privada Norbert Wiener, 2020-12-10) Moy Diaz, Brenda; Ortiz Arévalo, Yesenia Edith; Félix Véliz, Luis Miguel Visitación
The species Hypericum silenoides Juss "Canchalagua," native to the Cajamarca department, is a plant with various medicinal applications. The Objective of this research was to determine the antibacterial activity against Cutibacterium acnes and the antioxidant activity of the hydroalcoholic extracts from the leaves, flowers, stem, and root of Hypericum silenoides Juss, 'Canchalagua.' The Method employed consisted of preparing the hydroalcoholic extracts of the leaves, flowers, stem, and root of Hypericum silenoides Juss, followed by a solubility test and qualitative analysis to identify the metabolites. To determine the antibacterial activity against Cutibacterium acnes (ATCC 6919), the disk diffusion method was performed. For antioxidant activity, the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical method was used for evaluation. Results: The microbiological assay showed that the positive control group presented a larger diameter of the inhibition halo compared to the plant species extracts studied. The hydroalcoholic extract of the flowers showed greater antibacterial activity compared to the extracts of the leaves, stem, and root. The hydroalcoholic extract of the leaves of Hypericum silenoides Juss, 'Canchalagua,' presented the highest antioxidant activity with an IC50 of 54.53 µg/mL, followed by the hydroalcoholic extract of the flowers with an IC50 of 57.05 µg/mL, compared to the control (Trolox) with a p < 0.05. Conclusion: The hydroalcoholic extracts of the leaves, flowers, stem, and root have antibacterial activity against Cutibacterium acnes and antioxidant activity.
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Actividad antioxidante del extracto etanólico del mesocarpio del fruto de Hylocereus undatus “pitahaya” e identificación de los fitoconstituyentes
(Universidad Privada Norbert Wiener, 2017-11-08) Figueroa Díaz, Susana Lastenia; Mollinedo Moncada, Ofelia; Félix Véliz, Luis Miguel Visitación
Antioxidants are essential in the human body for preventing oxidative damage, and they can be obtained from different sources such as fruits and plants. The objective of this research was to evaluate the antioxidant activity of the ethanolic extract of the mesocarp of Hylocereus undatus (“pitahaya”) fruit and to determine its phytoconstituents. This quasi-experimental, analytical, descriptive, and prospective study prepared the ethanolic extract and evaluated its antioxidant activity using the DPPH method (2,2-diphenyl-1-picrylhydrazyl, Brand-Williams W). The antioxidant activity was expressed as IC50, with a result of 1.331 μg/mL, indicating significant antioxidant potential. Phytochemical analysis identified carbohydrates, reducing sugars, flavonoids, phenolic compounds, steroids, and alkaloids. In conclusion, the ethanolic extract of the mesocarp of Hylocereus undatus fruit shows antioxidant activity and may be considered a natural source of antioxidants.
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Actividad diurética del extracto hidroalcohólico de las hojas secas de la Persea americana Mill "palta fuerte"
(Universidad Privada Norbert Wiener, 2018-07-05) Bonifaz Monrroy, Nathali Dámariz; Muñiz Mayta, Liseth; Félix Véliz, Luis Miguel Visitación
The present study was conducted with the objective of determining the diuretic activity of the hydroalcoholic extract of dried leaves of Persea americana Mill. “Palta fuerte” in rats. The type of study was experimental and prospective, carried out in the natural products and animal facility laboratories of the Pharmacy and Biochemistry Department at Norbert Wiener University. The sample was collected in the province of Cañete, department of Lima. The hydroalcoholic extract was prepared for solubility testing, phytochemical analysis, and determination of diuretic activity using the Naik et al. method in rats divided into five groups of five each: Group I was the control, Group II received hydrochlorothiazide, and Groups III, IV, and V received doses of 100, 200, and 400 mg/kg of the extract. The percentage of urinary volumetric excretion, diuretic activity, and electrolyte quantification (Na⁺, K⁺, and Cl⁻) were calculated. It was determined that the extract is soluble in polar solvents and insoluble in non-polar solvents; the secondary metabolites present were tannins, saponins, phenols, alkaloids, and flavonoids. The percentages of urinary volumetric excretion were 28%, 30%, and 46% at doses of 100, 200, and 400 mg/kg, respectively, compared to hydrochlorothiazide which was 49%. The diuretic activity was 81%, 85%, and 95% at doses of 100, 200, and 400 mg/kg, respectively (p < 0.05); and significant differences were also observed with respect to electrolytes. In conclusion, it was demonstrated that the hydroalcoholic extract of the dried leaves of Persea americana Mill. “Palta fuerte” presented moderate diuretic activity.
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Actividad laxante del extracto hidroalcohólico del fruto Hylocereus undatus (Haw.) Briton & Rose "pitahaya roja" en ratones albinos de la especie Mus musculus
(Universidad Privada Norbert Wiener, 2018-05-14) Berrospi Cristobal, Rosy Katherin; Sánchez Barrera, Mirtha Nancy; Félix Véliz, Luis Miguel Visitación
Today, constipation is a very common problem that can occur at any age. In response, the World Health Organization (WHO) has estimated that more than 80% of the population uses traditional medicine. The sample was collected in the town of Esperanza Alta (La Virgen) in the Huaral district and taxonomically classified at the Natural History Museum of the National University of San Marcos (UNMSM). The purpose of this research was to evaluate the laxative activity of the hydroalcoholic extract from the fruit of Hylocereus undatus (Haw) Britton & Rose, 'red pitahaya,' in albino mice (Mus musculus) using the intestinal transit method. The research was experimental, explanatory, analytical, and prospective. A total of 50 albino mice were used, randomly distributed into seven groups of six animals each. The extracts were administered orally at concentrations of 100, 200, 300, 400, and 600 mg/kg. The positive control group received Bisacodyl (0.25 mg/kg), and the negative control received distilled water. Thirty minutes later, all groups were administered 5% activated charcoal at a dose of 0.1 mL/10 g of body weight. After another 30 minutes, the animals were sacrificed with ether, and a laparotomy-type dissection was performed to measure the distance the charcoal traveled through the small intestine. In conclusion, the laxative activity of the hydroalcoholic extract was confirmed, with an intestinal transit of 74.13% observed at a 400 mg/kg dose. The following phytoconstituents were identified: reducing sugars, saponins, flavonoids, phenolic compounds, alkaloids, fatty compounds, and quinones.
Acceso abierto
Caracterización química analítica del extracto vegetal hidroalcohólico de las hojas y tallos de Dracontium aff. spruceanum (Schott) G.H. Zhu
(Universidad Privada Norbert Wiener, 2021-08-06) Barreto Sánchez, Guisela Tereza; Vilchez Merjildo, Rocío Nathaly; Félix Véliz, Luis Miguel Visitación
The purpose of this research was to characterize the components of the hydroalcoholic extract from the leaves and stems of Dracontium aff. spruceanum (Schott) G.H. Zhu and to perform a chemical analytical interpretation of them through chemical reactions. The plant species, Dracontium aff. spruceanum (Schott) G.H. Zhu, is native to the city of Juanjuí in the Mariscal Cáceres locality (San Martin Region). It was collected in the village of Juanjuí, and its taxonomy was later verified at the Lima Museum of History. The specimen was disinfected and dried, and the sample fragments (root and leaves) were separated. Hydroalcoholic extracts were then prepared, and the present phytoconstituents were determined, including flavonoids, alkaloids, reducing sugars, phenolic compounds, free amino groups, and steroids. In conclusion, the hydroalcoholic extract of Dracontium aff. spruceanum contains metabolites whose presence was demonstrated through chemical reactions, making it a species of high interest.
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Conocimiento y uso de anticonceptivos hormonales en pacientes del programa de planificación familiar del centro de salud San Sebastian-Lima, 2022
(Universidad Privada Norbert Wiener, 2022-11-25) Condezo Cruz, Consuelo; Félix Véliz, Luis Miguel Visitación
The correct use of contraceptive methods implies an appropriate knowledge about their characteristics, purpose, mode of use and side effects, especially after completing the orientation at the health center, therefore the objective was to determine the knowledge and use of hormonal contraceptives in patients of the family planning program of the San Sebastian-Lima 2022 health center in a sample of 128 patients through a descriptive and cross-sectional study. It is reported that the socioeconomic factors that present a young population of 48.8% between 18 and 25 years of age with medium education with 56.8% at the secondary level and from medium to low socioeconomic level due to their status as employees with 45.6% and 19.2% housewives. Regarding knowledge, it can be concluded that 56.0% have a medium level of knowledge about hormonal contraceptives, followed by 26.4% with low knowledge and the remaining 17.6% with a high level of knowledge. Hormonal contraceptive practice shows that 63.2% of the people use it to prevent pregnancy, with 51.2% of cases using it for 2 to 5 years, with injections being the most used contraceptive with a relative frequency of 51.2%. The experience with the use of hormonal contraceptives shows that 49.6% use the contraceptive ampoule and weight gain is the most mentioned side effect with 52.8%. It is concluded that the knowledge is average in its various nuances consulted and the majority use it to prevent pregnancy; while attention should be paid to the knowledge of its side effects which shows a tendency to stop using them for the same reason.
Acceso abierto
Cuantificación de betalainas y actividad hipoglucemiante del extracto hidroalcohólico de pulpa y de cáscara de Hylocereus monacanthus (pitahaya roja)
(Universidad Privada Norbert Wiener, 2021-12-10) Balvín Esteban, Juana Iris; Huamán Labán, Kenni Yordan; Félix Véliz, Luis Miguel Visitación
The objective of this study was to quantify betalains in the aqueous extract (AE) and evaluate the hypoglycemic activity of the hydroalcoholic extract (HE) from the peel and pulp of H. monacanthus (red pitahaya) administered orally in alloxan-induced diabetic rats. 45 male Holtzman strain rats with a body weight of 100-130 g were used. The animals were distributed into nine groups: a negative control, a positive control, HE of pulp and peel (400, 500, and 600 mg/kg), and a group treated with glibenclamide (10 mg/kg). Diabetes was induced by intraperitoneal injection of alloxan (160 mg/kg), and glucose levels were measured with an Accu-Chek glucometer. Both the glibenclamide and the 600 mg/kg HE of H. monacanthus peel showed a hypoglycemic effect. However, the HE of the pulp showed no difference in effectiveness after 7 days of administration. The AE of the peel had a higher concentration of betalains. It is concluded that the HE of H. monacanthus (600 mg/kg oral dose) decreased blood glucose by 56% in alloxan-induced diabetic rats.
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Cumplimiento de buenas practicas de prescripción y determinacion de interacciones medicamentosas con ivermectina en tiempos de COVID-19 en recetas médicas atendidas en la farmacia del Centro de Salud Unidad Vecinal N° 3 – mayo a diciembre 2020
(Universidad Privada Norbert Wiener, 2022-04-27) Curo Guevara, Sara Elizabeth; Mendoza Baldeón, Gonzalina; Félix Véliz, Luis Miguel Visitación
The global COVID-19 health emergency has created a need to find medications to help treat and combat it. In this context, Ivermectin was established as an option frequently recommended by doctors, making it essential that it be correctly prescribed and dispensed to patients. Objective: To determine drug interactions in ivermectin prescriptions filled at the pharmacy of Neighborhood Health Center No. 3 from May to December 2020, in compliance with good prescribing practices. Methodology: This was a descriptive study, supported by the use of forms for data collection from 204 prescriptions at the Health Center's pharmacy. Results: Prescriber data was completed in over 95% of prescriptions, and patient data had even higher completion rates, always exceeding 97%. Medication data completion surpassed 98%. Drug interactions were found in 81 prescriptions, all of which were of moderate severity with a potential clinical manifestation. No pharmacological follow-up was performed to determine a real clinical manifestation. Furthermore, all 81 (100%) of the interactions were potential pharmacokinetic interactions, and none were potential pharmacodynamic interactions. Conclusion: Although good prescribing practices were well implemented, a key finding is that potential drug interactions were present in the patients' treatments, as identified through information searches.
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Cumplimiento de las buenas prácticas de prescripción y análisis de las buenas prácticas de dispensación y expendio en recetas médicas atendidas en Botica Latina y Botica Líder durante el periodo enero–marzo 2019
(Universidad Privada Norbert Wiener, 2022-11-25) Castañeda Salazar, Lorena Jaqueline; Hernández Medina, Shirley Olga; Félix Véliz, Luis Miguel Visitación
The purpose of this thesis was to verify compliance with Good Prescribing Practices (GPP) and analyze Good Dispensing and Sales Practices in Botica Latina and Botica Líder in the San Martín de Porres and San Juan de Lurigancho districts, respectively, during the period of January–March 2019. A descriptive and prospective study was conducted, in which 270 medical prescriptions were evaluated and received from hospitals, clinics, solidarity hospitals, polyclinics, and private practices. 106 were from Botica Latina and 164 were from Botica Líder. To evaluate compliance with Good Prescribing Practices, the Manual of Good Prescribing Practices from the Ministry of Health and the General Directorate of Medicines, Supplies, and Drugs of Peru was used, as well as the respective manual for the analysis of good dispensing practices. It was found that 78.5% (212 prescriptions) omitted the patient's age, 76.3% (206 prescriptions) omitted the diagnosis, and 93% (251 prescriptions) omitted the issuance and expiration date. 65.2% (176 prescriptions) omitted the INN (International Nonproprietary Name), 43% (116 prescriptions) omitted the concentration, and 39.3% (106 prescriptions) omitted the dose frequency. Consequently, it is concluded that there is non-compliance with Good Prescribing Practices, which will limit dispensing in both districts.
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Efecto antibacteriano in vitro del extracto etanólico de tres variedades de semillas (blanca, roja y negra) de Chenopodium quinoa (Quinua)
(Universidad Privada Norbert Wiener, 2025-07-01) Herrera Manrique, Marion Consuelo; Viera Chambergo, Yasmin Ysbeth; Félix Véliz, Luis Miguel Visitación
Antibiotic resistance is alarming worldwide, with Staphylococcus aureus, Escherichia coli and Pseudomona aeruginosa being fundamental protagonists of this phenomenon, given the aforementioned reason, the work aims to: To demonstrate the in vitro antibacterial effect of the ethanolic extract of the three seed varieties (white, red and black) of Chenopodium quinoa (quinoa). Methodology: quantitative approach, explanatory; seed population (white, red and black) of Chenopodium quinoa, sample was 1 kilo of Chenopodium quinoa for each type, petri dishes were used which was distributed of 3 plates for each biological strain and non-probabilistic sampling by intention. Results: anthocyanins, saponins, flavonoids, among other metabolites, were identified. At the microbiological level, significant inhibition halos of (p<0.05) were evidenced with 9.29 mm (red quinoa), 8.76 mm (white quinoa) and 9.57 mm (black quinoa) against Staphylococcus aureus, on the other hand, no significant halos were evidenced against Escherichia coli and Pseudomona aeruginosa front, only halos of 8.35 mm and 8.46 mm were evidenced for white and black quinoa respectively. Conclusion: The ethanolic extract of the three varieties of Chenopodium quinoa seeds (white, red and black) was determined to have an antibacterial effect in vitro.
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Errores de prescripción en recetas atendidas en farmacia central de pacientes hospitalizados del Hospital Regional Docente de Cajamarca, 2020
(Universidad Privada Norbert Wiener, 2021-08-06) Carmona Bazán, Adela; Félix Véliz, Luis Miguel Visitación
The objective of this research was to determine prescription errors in prescriptions filled at the central pharmacy for hospitalized patients at the Regional Teaching Hospital of Cajamarca in 2020. METHODOLOGY: An inductive method was used to study the behavior of each dimension. The research approach was a quantitative analysis, with a basic study type and a descriptive level. The design was non-experimental, as the variable was not intentionally manipulated. The POPULATION consisted of 5,840 prescriptions filled from the Surgery, Medicine, Gynecology, and Pediatrics departments. The SAMPLE was 361 prescriptions, for which a systematic random start sampling method was used. Data was collected by reviewing the prescribed prescriptions. The technique used was a documentary analysis using a checklist. The instruments were validated by expert judgment, and SPSS Version 25.0 was used. Data analysis was performed by calculating the percentages and comparing them with the results from other national and international research to better understand the issue of prescription errors.
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Estilos de vida relacionados con el consumo de plantas medicinales en personas que acuden al Mercado Cooperativa de Pro de Los Olivos. Lima. 2024
(Universidad Privada Norbert Wiener, 2025-03-17) Coronel Aguilar, Leticia; Leandro Rufino, Maria Magdalena; Félix Véliz, Luis Miguel Visitación
The present investigation had as main objective: Identify the relationship between lifestyles and the consumption of medicinal plants in people who go to the Mercado Cooperativa of Los Olivos Method: The research carried out was basic, with an observational, descriptive and cross-sectional design. A questionnaire validated through expert judgment was used as an instrument, applying it to a sample of 196 people. The data obtained were analyzed using SPSS software in version 25. Results: 63% of the participants were women, 35% had secondary education, 37% were married, and 24% were older adults. The correlation analysis between lifestyles and the consumption of medicinal plants showed a significant relationship, with a p value = 0.000 and a Spearman's Rho coefficient of 0.994. Conclusion: It was identified that there is a strong positive correlation between lifestyles and the consumption of medicinal plants in people who attend the Mercado Cooperativa de Pro of Los Olivos. Lima 2024, This result is supported by a Spearman's Rho correlation coefficient of 0.994 and a p value = 0.000.
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Estudio de utilización de antibacterianos de reserva en las unidades de cuidados críticos e intermedios del Hospital Nacional Dos de Mayo durante 2012–2013
(Universidad Privada Norbert Wiener, 2015) Colán Ramos, Carlomagno Ademir; Gaspar Sales, Óscar Marcelo; Félix Véliz, Luis Miguel Visitación
The World Health Organization (WHO) defines drug utilization as “the marketing, distribution, prescription, and use of drugs in a society, with particular attention to the resulting medical, social, and economic consequences.” Therefore, drug utilization studies are essential to assess the benefit/risk ratio of active pharmaceutical ingredients, detect deviations and distortions, and consequently implement appropriate corrective measures. The objective of this study was to determine the consumption and expenditure of reserve antibacterials in the critical and intermediate care units of the Hospital Nacional Dos de Mayo during 2012–2013. Using the methodology recommended by the WHO for drug utilization studies in hospitals, data were presented in defined daily doses (DDD) per 100 bed-days (DDD/100 bed-days). Consumption data were obtained from the pharmacy management program, while the number of days, number of beds, and bed occupancy index were obtained from the Department of Statistics. During 2012–2013, it was determined that the carbapenem group ranked first in consumption in DDD/100 bed-days. Among these, meropenem was the most used in 2012, while imipenem + cilastatin was most used in 2013. Regarding expenditure, colistin accounted for 42% of the total cost during the study period. In conclusion, consumption and expenditure of reserve antibacterials quadrupled in 2013 compared to 2012; furthermore, no significant correlation was found between consumption and the bed occupancy index.
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Estudio etnofarmacológico de las plantas medicinales con mayor uso significativo en la comunidad del centro poblado Tambolic, distrito de Jamalca, Utcubamba – Amazonas. Mayo–junio de 2018
(Universidad Privada Norbert Wiener, 2019-09-06) Aguilar Güimac, Eduar Glicerio; Montalvo Rodriguez, Gina Pilar; Félix Véliz, Luis Miguel Visitación
The objective of this research was to identify, through an ethnopharmacological study, the medicinal plants with the greatest significant use in the community of the Tambolic populated center, Jamalca district, Utcubamba – Amazonas, during May-June 2018. Method: The recommendations established by the Traditional Medicine of the Islands (TRAMIL) were followed, considering two working stages: field and post-field. The field stage involved semi-structured interviews with 54 people (men and women of older age in the family group). The post-field stage involved the analysis of the TRAMIL significant use level index and phytochemical analysis. Results: 31 plants with medicinal uses were reported, distributed across 23 families, with the Lamiaceae family being the most representative, with three species: Rosmarinus officinalis L. (Rosemary), Mentha pulegium L. (Pennyroyal), and Ocimum basilicum L. (Basil). The gastrointestinal category was the most frequent ailment. It was also determined that the leaves are the most utilized parts of the plants (56.76%). The most habitual mode of preparation is infusion (26.47%). The primary route of administration is oral (62.86%), followed by the topical route (25.17%). Conclusion: The ethnopharmacological study identified that the medicinal species with the greatest significant use in the Tambolic populated center community are: Mentha pulegium L. (Pennyroyal), Plantago major L. (Plantain), and Verbena officinalis L. (Vervain). All of them were cited with a frequency greater than 20% for a specific health problem.
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Estudio etnofarmacológico de las plantas medicinales y sus efectos en enfermedades gastrointestinales en Cajabamba, Cajamarca – Perú, 2023
(Universidad Privada Norbert Wiener, 2023-11-21) De La Cruz Medina, Luz Clarita; Félix Véliz, Luis Miguel Visitación
The ethnopharmacological study integrates disciplines such as ethnobotany, chemistry, and pharmacology to scientifically investigate the therapeutic properties of natural products that were traditionally used or are currently applied to treat health problems such as gastrointestinal diseases, which are common among the population. The objective of this research was to describe how ethnopharmacological studies help identify the most commonly used medicinal plants by local residents and their effects on gastrointestinal diseases in Cajabamba, Cajamarca, Peru, 2023. The methodology used was basic type, descriptive level, and non-experimental cross-sectional design. The sample consisted of 130 respondents. The technique used was a survey, and the instrument was a questionnaire with 96% reliability. Results: Fifteen medicinal plants were reported, of which seven were the most frequently mentioned by the population: Minthostachys mollis (Chanca or muña), Lantana angustibracteata (Botonsillo), Tagetes filifolia Lag. (Anisquegua), Otholobium pubescens (Culén), Stachys arvensis L. (Zupisacha), Pilea sp (Contrayerba), and Ageratina sternbergiana (Warme). The most commonly used part of the plants was the leaves (57.7%), the most frequent preparation method was infusion (83.1%), and the most common administration frequency was daily use (58.5%). In the phytochemical analysis, the presence of primary and secondary metabolites was identified, including carbohydrates, reducing sugars, phenolic compounds, flavonoids, free amino groups, alkaloids, and steroids. Conclusion: Through ethnopharmacological study, the most commonly used medicinal plants beneficial for gastrointestinal diseases were identified, such as Minthostachys mollis (Chanca or muña).
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Experiencia de las personas de la tercera edad en el uso del plantago major (llantén) en el poblado de Bayóvar San Juan de Lurigancho Lima Metropolitana – 2023
(Universidad Privada Norbert Wiener, 2024-08-27) Cabello Guadalupe, Sara Nélida; Davila De La Cruz, Tania; Félix Véliz, Luis Miguel Visitación
The objective of this research work was to evaluate the experiences of elderly people in the use of Plantago major (llantén) in the town of Bayóvar San Juan de Lurigancho 2023. Method: a descriptive level study was carried out, quantitative approach, observational and cross-sectional design in a sample of 178 elderly people, to whom a questionnaire was administered through surveys. Result: 75% of the elderly people who used Plantago major (llantén) were female, the most common age being 60 to 65 years, 29% purchased the product on the market, the most recommended source mentioned was the friend 36%, in ailments and method of preparation most treated are joint pain and bumps or sprains, the plaster was used mostly (33.7 and 39.1% respectively) compared to other diseases; Likewise, for the symptom of pain, the plaster was used (45%) and for inflammation, inhalation was mostly used (47.4%). Conclusion: It was determined that, according to their experiences, 100% of the elderly people who used Plantago major (llantén) in the town of Bayóvar San Juan de Lurigancho would recommend its use because they all presented relief or improvement in their ailments and/or illnesses.
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Identificación de metanol y la concentración del alcohol de 70° en las diferentes marcas comercializadas en el Mercado Central – Lima 2023
(Universidad Privada Norbert Wiener, 2023-12-07) Huamán Ñaupa, Mario Amadeo; Félix Véliz, Luis Miguel Visitación
This study uses a descriptive observational method, a quantitative approach, and an analytical, non-experimental descriptive design. Its objective is to evaluate the presence of methanol and the concentration of alcohol in 70° medicinal alcohol from different brands sold in the central market of Lima in August 2023. The methodology used consisted of a random probabilistic sampling of 20 one-liter samples of 70° medicinal alcohol. These were purchased from both pharmaceutical locations (Sample B: 10 samples from pharmacies and drugstores) and other commercial stores (Sample A: 10 samples from street vendors, shopping centers, and small shops). Methanol was identified using chromotropic acid as a reagent, in accordance with Peruvian Technical Standard (NTP) 211.007:2014 for sensory evaluation. Physicochemical determinations (density, pH, alcohol concentration) were conducted according to the United States Pharmacopeia (UPS) and NTP 211.007:2014. Positive results for methanol were found in 90% of samples from commercial stores and 20% of samples from pharmaceutical locations. The alcohol concentration results were all below 70°, with an average of 59° in commercial stores and 68° in pharmaceutical locations. The study concluded that a significant difference exists in the identification of methanol in 70° medicinal alcohol sold in commercial stores versus pharmaceutical locations. Similarly, there is a significant difference in the alcoholic concentration of the 70° medicinal alcohol sold in these two types of locations in Lima - Cercado, August 2023.