Nutrición Humana
URI permanente para esta colecciónhttps://hdl.handle.net/20.500.13053/21
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Examinando Nutrición Humana por Línea de Investigación "Salud y bienestar"
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Ítem Acceso abierto Caffeine supplementation and physical performance in athletes with variations of genetic polymorphisms(Universidad Privada Norbert Wiener, 2022-03-25) Recoba Obregón, Paulo Eder; Bohórquez Medina, Andrea LisbetSports caffeine supplementation is suitable to improve physical performance in elite and recreational athletes according to sport classifications (endurance, strength or mixed) to avoid the presence of fatigue. For this secondary research entitled Critical Review: Caffeine supplementation and physical performance in athletes with genetic polymorphism variations", the objective was to identify the effect of caffeine supplementation on physical performance in these types of athletes. Being the clinical question: Will caffeine supplementation (capsules) improve physical performance in elite or recreational athletes with genetic polymorphism variations?, the methodology used was Evidence-Based Nutrition (NuBE) and the databases used for the information search were "PUBMED, MEDLINE, GOOGLE SCHOLAR, EMBASE," reporting 192 clinical investigations from which 12 articles were chosen and evaluated by the critical reading tool CASPE, where finally the randomized clinical trial entitled: Caffeine, CYP1A2 genotype and endurance performance in athletes" was selected; having a level of evidence: AI and Grade of Recommendation: Strong, according to the researcher's experience. It was concluded through critical commentary that caffeine supplementation is recommended to improve physical endurance performance in elite athletes with CYP1A2 genetic polymorphism for homozygotes of the A allele (AA).Ítem Acceso abierto Comparative efficacy and safety of phosphate binders in hyperphosphatemic patients with chronic kidney disease.(Universidad Privada Norbert Wiener, 2022-05-30) Zavaleta Gavidia, Rosa Haydee; León Cáceres, Johanna del CarmenPhosphorus binders reduce the absorption of phosphorus obtained from the diet in the gastrointestinal tract. Critical review entitled: The use of phosphorus binders reduce hyperphosphatemia in patients over 18 years of age with chronic kidney disease and on hemodialysis, the objective was to prepare the professional critical commentary, according to the clinical studies related to the subject, with the clinical question: Does the use of phosphorus binders reduce hyperphosphatemia in patients over 18 years of age with Chronic Kidney Disease and on HD?, the method based on evidence from NUBE was used. The search for information was carried out in PUBMED, SCIELO, SCIENCE DIRECT, finding 344 articles, of which 10 articles were selected, evaluated by the critical reading tool CASPE, finally, a Meta-analysis entitled comparative efficacy and safety of phosphorus binders in patients with hyperphosphatemia with chronic kidney disease was selected, with level of evidence AII and Strong Recall Grade; Based on the researcher's experience, critical commentary determined that iron-based phosphate binding agents were the preferred agents in terms of both efficacy and safety.Ítem Acceso abierto Critical review: Effect of dietary sodium restriction on blood pressure and biomarkers in patients with chronic kidney disease without dialysis.(Universidad Privada Norbert Wiener, 2022-05-31) Aroni Dominguez, Elena; León Cáceres, Johanna del CarmenThe present research, entitled: Critical review: effect of dietary sodium restriction on blood pressure and biomarkers in patients with chronic kidney disease without dialysis. The objective is to prepare the critical review based on the search and analysis of clinical studies about dietary sodium restriction and its effects on blood pressure and biomarkers in patients with chronic kidney disease. The question was: Does nutritional intervention based on dietary sodium restriction have effects on blood pressure and biomarkers in patients with chronic kidney disease without dialysis? The methodology of the principle of evidence-based nutrition was used. Information was searched in the PUBMED, SCIELO, SCIENCE DIRECT databases. 29 articles were found, 10 were chosen. It was evaluated using the CASPE critical reading tool, choosing the study entitled; Restriction of salt in the diet in chronic kidney disease: a meta-analysis of randomized clinical trials; it obtained a level of evidence AII, strong recommendation grade. Conclusion: Moderate sodium reduction from 2 to 2.3 g per day for an average of 4 weeks reduces blood pressure, albuminuria and proteinuria in renal patients. Further studies are required to determine greater effects.Ítem Acceso abierto Critical review: Efficacy of exercise in blood pressure control in adults.(Universidad Privada Norbert Wiener, 2022-06-16) Olano Yalta, Anthonny Micheel; León Cáceres, Johanna del CarmenIt has been described that not only pharmacological treatment helps in the control of blood pressure, but also physical activity, especially aerobic exercises, which are one of the main effective treatments for regulating and controlling hypertension. This secondary research, titled Critical Review: Effectiveness of Exercise in Blood Pressure Control in Adults, aimed to identify whether exercises are effective in controlling blood pressure in adults. The methodology used was Evidence-Based Nutrition (NuBE). The information search was conducted in PUBMED and SCIENCE DIRECT, finding 36 articles, with 11 selected for critical evaluation using the CASPE tool. Finally, the randomized clinical trial titled Long-term home-based exercise is effective to reduce blood pressure in low-income Brazilian hypertensive patients: A controlled trial was chosen, which has an AI level of evidence and a strong recommendation grade, according to the researcher's expertise. The critical comment concluded that physical activity interventions, including low to moderate intensity walking and stretching exercises, are the only way to improve the patient's quality of life.Ítem Acceso abierto Critical review: The effect of cholecalciferol supplementation improves vascular function in adult patients with chronic kidney disease.(Universidad Privada Norbert Wiener, 2022-05-25) Ríos Barbarán, Martín; Dávila Córdova, Jennifer EstefaniaChronic kidney disease (CKD) is a public health problem of global relevance; since it is related to the increased risk of cardiovascular disease as kidney failure progresses, vitamin D deficiency is associated with mortality in patients with CKD, which could mitigate the risk of cardiovascular disease in CKD. The present secondary research entitled: Critical review: The effect of cholecalciferol supplementation improves vascular function in adult patients with chronic kidney disease", aimed to know the effect of cholecalciferol supplementation in improving vascular function in adult patients with chronic kidney disease. The clinical question was: Does the effect of cholecalciferol supplementation improve vascular function in adult patients with Chronic Kidney Disease? The Nutrition Based on Evidence (NuBE) methodology was used. The information search was performed in PUBMED and COCHRANE, finding 37 articles, of which 11 were selected and evaluated by the critical reading tool CASPE. Finally, the Randomized Clinical Trial entitled "A randomized trial of vitamin D supplementation on vascular function in CKD" was selected, which has an AI level of evidence and Strong Grade of Recommendation, according to the researcher's expertise. The critical commentary allowed to conclude that the use of cholecalciferol supplements improves vascular function through endothelial function indicators and circulating biomarkers, with cholecalciferol supplementation being considered as a nutritional treatment to positively improve in adult patients with chronic kidney disease; at the same time, it is proposed to continue carrying out clinical studies in which the number of participants is greater and the intervention period similar to the selected clinical trial.Ítem Acceso abierto Effect of dietary fiber on the reduction of uremic toxins in adult patients with chronic kidney disease(Universidad Privada Norbert Wiener, 2022-05-25) Laura Ticona, María Elena; León Cáceres, Johanna del CarmenChronic kidney disease (CKD) develops due to gradual loss of kidney function. In CKD, a deficiency in dietary fiber intake is a factor that leads to intestinal dysbiosis contributing to uremic toxicity. The present secondary research aims to determine the effect of dietary fiber in reducing uremic toxins in adult patients with CKD. The Evidence-Based Nutrition (EBN) methodology was used. The information search was carried out in Pubmed, Scielo, Redalyc, finding 37 articles, 10 articles being selected, which have been evaluated by the CASPE critical reading tool, selecting the research entitled "The Role of Dietary Fiber Supplementation in Regulating Uremic Toxins in Patients With Chronic Kidney Disease: A Meta-Analysis of Randomized Controlled Trials". The critical commentary allowed to conclude that dietary fiber supplementation decreased the levels of IS, pCS, BUN and AU in patients with CKD, so dietary fiber supplementation is recommended in patients with CKD.Ítem Acceso abierto Effect of omega 3 in the treatment and evolution of the patient with covid-19(Universidad Privada Norbert Wiener, 2022-04-22) Ponce Urquia, Xavier Franckling; Bohórquez Medina, Andrea LisbetCOVID-19 is a disease that is now considered a pandemic caused by the recent type of coronavirus called SARS-CoV-2 and represents a major threat to medicine in all countries. This virus can be transmitted between people through respiratory droplets, fomites and contact. Complications from COVID-19 represent 10-15% of all cases, and can lead to the person being admitted to the ICU and are often fatal. The mortality rate for COVID-19 is 2% and the hospital mortality rate is approximately 10%. Although corticosteroids, antiviral therapy and mechanical respiratory support have been used for treatment, there is still no specialized treatment for COVID-19 to date. The present research aimed to discover whether Omega-3 supplementation in the diet can reinforce the treatment and evolution of the population with COVID-19. The critical commentary led to the conclusion that omega-3 supplementation should be considered as a treatment in cases of COVID-19, since everything indicates that its action is extremely beneficial; however, more research is needed to definitively determine the efficacy of omega-3 against COVID-19.Ítem Acceso abierto Effect of omega 3 supplementation in the treatment of patients with non-alcoholic hepatic steatosis(Universidad Privada Norbert Wiener, 2022-05-16) Cutimbo Huanca, Mayda Marianela; Bohórquez Medina, Andrea LisbetNon-alcoholic fatty liver disease (NAFLD), defined as liver damage resulting from the accumulation of excess fat within hepatocytes, which leads to a chronic inflammatory process. The aim of the study was to identify the effect of omega-3 supplementation in patients with NASH; to do so, the research question was formulated: What is the effect of omega-3 supplementation in patients with NASH? Subsequently, the bibliographic search process was carried out in the PUBMED and EMBASE databases, selecting a total of 17 clinical studies, evaluated according to the CASPE tool, for the development of critical reading. Finally, the double-blind randomized clinical trial entitled "Omega-3 polyunsaturated fatty acids in treating non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial" was analyzed, rated with a level of evidence A and a grade of recommendation Strong. The critical analysis concludes that in patients with NASH, supplementation with omega-3 polyunsaturated fatty acids, such as linseed and fish oils, has a significant impact on the plasma lipid profile. Furthermore, increased plasma levels of these PUFAs were associated with improved liver histology and morphology.Ítem Acceso abierto Effect of the use of probiotics in the management of stress and depression in adults(Universidad Privada Norbert Wiener, 2022-04-28) Uriarte Sánchez, Edward Josehp; Bohórquez Medina, Andrea LisbetProbiotics are live microorganisms that provide health benefits. Depression is a very common pathology that could cause emotional as well as physical problems. Recent research has shown a significant bidirectional communication called the gut-brain axis, as well as a relationship between the alteration of the enteric microbiome and psychiatric disorders, which would allow for further studies and the proposal of alternative therapies. The clinical question was: What is the effect of using probiotics in managing stress and depression in adults? The information search was carried out in PUBMED, SCOPUS, SCIENCE DIRECT, and EMBASE, finding 150 articles, of which 21 were selected and evaluated by the CASPE critical reading tool, selecting the Randomized Clinical Trial: “Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota”, which has a level of evidence I and Grade of Recommendation I, according to the researcher's expertise. The critical commentary concluded that the use of probiotics to alleviate depressive symptoms is promising, mainly due to their potential anti-inflammatory effect, but additional double-blind randomized clinical trials and more rigorous studies are needed to support such conclusions.Ítem Acceso abierto Influence of flavonoid intake on the risk of developing colorectal cancer in adults.(Universidad Privada Norbert Wiener, 2022-05-30) Hamasaki Matos, Angie Joyce; Bohórquez Medina, Andrea LisbetColorectal cancer is classified as the third most common cancer and the second most deadly in the world and dietary components can be protective factors. Therefore, the present academic work aims to evaluate updated evidence through a critical clinical commentary on the influence of flavonoid consumption in reducing the risk of developing colorectal cancer in adults. To do so, the five stages of NuBE were used and, through the CASPe tool, the scientific articles were classified according to their degree of evidence. From the review and evaluation process, the article Dietary Flavonoids and the Risk of Colorectal Cancer: An Updated Meta-Analysis of Epidemiological Studies was selected. The study structures, describes and analyzes the data in a manner relevant to the type of study that the authors carry out. The statistical analysis is presented in a concise and precise manner, which would allow the study to be replicated. The discussion raised by the authors highlights the main findings and puts them into context by comparing them with similar works previously published. Finally, it can be concluded that it is necessary to generate more high-level scientific evidence that allows extrapolation of results to the general population.Ítem Acceso abierto Whole grain intake and colorectal cancer survival(Universidad Privada Norbert Wiener, 2022-04-28) Puma Castañeda, Medy Yohana; Bohórquez Medina, Andrea LisbetThis critical review is a secondary research entitled: "Whole grain consumption and colorectal cancer survival", which aims to discover the benefits of whole grain consumption for the survival of patients diagnosed with colorectal cancer from the first stage. The clinical question was: What is the effect of whole grain consumption on the survival of adult patients suffering from colorectal cancer from the first stage? The Evidence-Based Nutrition (NuBE) methodology was used. The information search was carried out in different databases such as Scopus, WOS, Science Direct, Pubmed, LILACS, Google scholar and Embase; Finding 165 articles, selecting 21 that have been evaluated by the critical reading tool CASPE, selecting the systematic review entitled "The Impact of Whole Grain Intake on Gastrointestinal Tumors: A Focus on Colorectal, Gastric, and Esophageal Cancers", which has a level of evidence AI and strong Grade of Recommendation, according to the researcher's experience. The critical commentary allowed to conclude that the consumption of whole grains favors to decrease the risk of colorectal cancer and improves the survival of patients with colorectal cancer, although in this last point it is suggested to carry out more research.