Examinando por Materia "Heparin"

Mostrando 1 - 8 de 8

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Comparative effectiveness of trisodium citrate and heparin for extracorporeal circuit anticoagulation in adults with renal failure undergoing renal replacement therapy.
(Universidad Privada Norbert Wiener, 2018-11-04) Espinoza Canales, Carolina Desidet De Jesús; Pretell Aguilar, Rosa Maria
Objective: To analyze and systematize the evidence on the effectiveness of trisodium citrate versus heparin for anticoagulation of the extracorporeal system in adult patients with renal failure undergoing renal replacement therapy. Materials and methods: A systematic review of eleven scientific articles with a maximum age of ten years. According to the type of research, 54.5% are systematic reviews, 18.2% are clinical trials, 18.2% are retrospective cohorts, and 9.1% are meta-analyses. Regarding quality, 81.8% are of high quality and 18.2% are of moderate quality. 36.4% of the evidence comes from China, followed by 36.4% from England, 9.1% from Switzerland, 9.1% from Austria, and 9.0% from Amsterdam. A summary table was prepared with the main data from each selected article. Results: 100% of the evidence indicates that the use of trisodium citrate is more effective for anticoagulation of the extracorporeal circuit in adult patients with renal failure undergoing renal replacement therapy, in terms of filter lifespan, lower bleeding risk, and less circuit loss. Conclusions: The use of citrate is more effective compared to heparin in adult patients undergoing renal replacement therapy for anticoagulation of the extracorporeal circuit.
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Effectiveness of the use of saline solution compared to the use of heparinized solution to patent the arterial line and avoid obstructions in intensive care unit patients
(Universidad Privada Norbert Wiener, 2020-02-16) Murillo Solis, Jufet Fabriccio; Arce Condor, Miguel Angel; Uturunco Vera, Milagros Lizbeth
Objective: Systematize the evidence about the effectiveness of the use of saline solution compared to the use of heparinized solution to permeabilize the arterial line and avoid obstructions in intensive care unit patients. Method: Review A review of the evidence available in the databases: MEDLINE, PUBMED, SCIELO AND COCHRANE LIBRARY has been carried out, from the years 2010 to 2019; Randomized, quasi-experimental, cross-sectional clinical trials on the use of heparin versus the use of saline to improve the patency of arterial catheters were included. Results: 10 articles were found, which discuss, compare and analyze the use of heparin to improve arterial catheter patency. Conclusions: Studies show that the use of heparin is associated with a lower incidence of arterial catheter obstruction, also increasing its average life and improving its duration. However, some articles showed little difference when choosing whichever solution was used.
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Effectiveness of unfractionated heparins versus low-molecular-weight heparins for the prevention of coagulation in patients with renal insufficiency undergoing hemodialysis.
(Universidad Privada Norbert Wiener, 2018-11-04) Rosado Gereda, Johana Lizbeth; Vicente Velasquez, Víctor Andrés; Borda Izquierdo, Alejandro
Objective: A systematic review of ten scientific articles was conducted, with a publication date of less than ten years, from the following databases: Scielo, Pubmed, Epistemonikos, Medline, and Google Scholar. Of the selected articles, 20% were systematic reviews and meta-analyses, 40% were randomized clinical trials, 20% cohort studies, and 20% case-control studies. The overall quality of evidence was high in 70% of the articles and moderate in 30%. The studies originated from the following countries: USA (30%), Canada (20%), Brazil (10%), Austria (10%), Israel (10%), Poland (10%), and the UK (10%). The GRADE system was used to identify the level of evidence. Results: According to the findings, 60% (n = 6/10) indicated that both heparins are equally effective in preventing coagulation in patients with renal failure undergoing hemodialysis. 30% (n = 3/10) suggested that low-molecular-weight heparin is more effective than unfractionated heparin, and 10% (n = 1/10) indicated that unfractionated heparin is more effective than low-molecular-weight heparin. Conclusions: Unfractionated heparin is as effective as low-molecular-weight heparin in preventing coagulation in patients with renal failure undergoing hemodialysis treatment.
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Efficacy of citrate compared to heparin in catheter sealing in hemodialysis patients
(Universidad Privada Norbert Wiener, 2018-03-25) Peralta Rojas, María Consuelo; Lino Perez, Jhomnela Pilar; Rivera Lozada de Bonilla, Oriana
Methodology: The study was a Systematic Review of 10 articles restricted to full-text articles. Selected articles were critically reviewed using the GRADE assessment system to identify the quality of evidence and strength of recommendations. Results: The results obtained from the reviews show that of the 10 scientific articles reviewed, 20% (n=2/10) report that the use of citrate is effective compared to heparin, with higher catheter survival rates and a more favorable side effect profile. 60% (n=6/10) indicate that citrate and heparin are similar as anticoagulants in sealing catheters; the use of sodium citrate does not present clear advantages in the prevention of infection complications compared to sodium heparin. 20% (n=2/10) report that there is no difference between citrate and heparin. Conclusion: It was concluded that heparin and citrate are effective in sealing catheters, with no significant differences found. In this regard, more comparable research studies are needed to discuss and conclude which recommendations should be transferred to clinical practice in hemodialysis.
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Efficacy of citrate compared to heparin in sealing catheters in patients with hemodialysis
(Universidad Privada Norbert Wiener, 2018-03-25) Peralta Rojas, María Consuelo; Lino Perez, Jhomnela Pilar; Rivera Lozada de Bonilla, Oriana
Methodology: the study was a Systematic Review of 10 articles whose search has been restricted to articles with full text, and the selected articles were subjected to critical reading, using the evaluation of the GRADE system to identify the quality of evidence and strength of recommendations . Results: The results obtained from the reviews show that of the total of 10 scientific articles reviewed, 20% (n=2/10) report that the use of citrate is effective compared to heparin, greater survival of the catheters, has a profile more favorable side effect. 60% (n=6/10) indicate that citrate and heparin are similar as anticoagulant in the sealing of catheters, the use of sodium citrate does not present clear advantages in the complications of infections compared to sodium heparin. 20% (n=2/10) report that there is no difference between citrate and heparin. Conclusion: it was concluded that heparin and citrate are effective in sealing catheters, there were no significant differences. In this sense, more comparable research studies are necessary to be able to discuss and conclude which recommendations should be transferred into clinical practice in hemodialysis.
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Efficacy of Citrate Versus Heparin Anticoagulation in Decreasing Bleeding in Patients With Acute Renal Failure on Continuous Renal Replacement Therapy
(Universidad Privada Norbert Wiener, 1905-07-09) Cabanillas Huamán, Augusto Enrique; Rosas Casique, Diana Beatriz; Remuzgo Artezano, Anika
Objective: Systematize the evidence on the effectiveness of citrate anticoagulation versus heparin to reduce bleeding in patients with acute renal failure on continuous renal replacement therapy. Results: The results obtained from the systematic reviews show that of the total of 10 scientific articles reviewed, 100% (n=10/10) report that the use of citrate anticoagulation is more effective compared to the use of heparin. , show that the implementation of a protocol, and the choice of first-line use of citrate anticoagulation is safe, and has more advantages than heparin, because it presents a lower risk of bleeding complications. and/or bleeding. Fernández states that the incidence of hemorrhage was (0% vs. 10.3%). Zhang indicated that citrate is able to reduce the risk of bleeding 0.28 (95% CI 0.15 0.50). Wu reported a statistically significant decrease in bleeding (RR, 0.34; 95% CI, 0, 17-0.65). Conclusions: 100% (n=10/10) show that the use of citrate anticoagulation is more effective compared to the use of heparin, because it significantly reduces the risk and complications of hemorrhage and/or bleeding.
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Efficacy of enoxaparin versus unfractionated heparin in the treatment of adult patients with acute coronary syndrome
(Universidad Privada Norbert Wiener, 1905-07-09) Villanueva Andrade, Raul Eduardo; Villanueva Torres, Ingrid Estela; Gamarra Bustillos, Carlos
Objective: Systematize and analyze the effectiveness of enoxaparin vs unfractionated heparin in the treatment of adult patients with acute coronary syndrome. Methodology: Observational and retrospective systematic review, the search has been restricted to articles with full text, and the selected articles underwent Jover evaluation to identify their level of evidence. Results: In the final selection, 9 articles were chosen, we found that 50% (05) correspond to Canada, with 30% (03) we find the United States, while with 10% (01) we find Korea and France respectively. Most of them are quantitative studies with 100%, mainly in the countries of Canada and the United States. Conclusions: Of the total of 9 articles systematically reviewed, 70% of the articles show that Enoxaparin is more effective than unfractionated heparin in the treatment of adult patients with acute coronary syndrome and 20% of the studies presented in the systematic review concludes that there are no significant differences between enoxaparins and low molecular weight heparin.
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Efficacy of the use of Sodium Chloride 0.9% vs Sodium Heparin in the patency of venous catheters
(Universidad Privada Norbert Wiener, 1905-07-09) Alarcón Quiroz, Shirley Paola; Wong Zárate, Samuel Christian; Gómez Gonzales, Walter Edgar
Objectives: Determine the effectiveness of using 0.9% sodium chloride versus sodium heparin on the patency of venous catheters. Materials and Methods: Observational and retrospective systematic review, the search has been restricted to 8 scientific articles with full text no older than 10 years, the selected articles underwent a critical reading to identify their level of evidence. Results: the results obtained (n=8), 25% (n=08/02), show that the use of heparin is more effective (7.8); 50% (n=08/04) showing the effectiveness of both methods (6, 9, 11,12) and finally we find 25% (n=08/02) showing the effectiveness of saline solution (10 ,13) and that the use of saline solution is preferable to avoid complications with heparin. Conclusions: it is concluded that sodium heparin vs 0.9% sodium chloride are equally effective for maintaining the permeabilization of venous catheters. Recommendations: The use of 0.9% sodium chloride is recommended for the patency of venous catheters because it has lower cost and complications.