Preparation of a blueberry drink and effect of its consumption on serum glucose
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Resumen
The blueberry is a berry native to North America. In Peru, it was reported that blueberry production grew at an average rate of 206% per year between 2012 and 2018. Studies mention the presence of large amounts of anthocyanins, which have important biological activities such as antioxidant, antimutagenic, and hypoglycemic effects. Blueberries also contain flavonoids, which play an essential role in protecting against oxidative damage. The phytochemical composition of blueberries changes depending on their ripening stage, which causes changes in the cell wall, resulting in softening of the fruit, which improves its taste but also makes it more vulnerable to physical and microbiological damage. Ripe blueberries have a very short post-harvest life. Due to the fruit's characteristics, a method is required to extend its shelf life. In South America, studies have shown that nine out of ten people consume sugary drinks daily, with an average intake of about 450 ml per day. In Peru, an annual per capita consumption of 100 liters was reported in 2015, with a trend to grow by about 3% each year. Given the trend of sugary drink consumption, the massive production of blueberries in our country, the premature deterioration of the fruit's surface, and the attributed phytochemical properties, this project aims to formulate a blueberry drink that will be pleasant to the public and evaluated for its effect on serum glucose, compared with other drinks on the market. It will be conducted in two phases: the first involves a sensory evaluation, and the second, a clinical trial related to its consumption.
Resumen
La presente investigación secundaria titulada como revisión crítica: Efecto del consumo de fructosa en niveles de ácido úrico plasmático en sujetos con posibilidad de enfermedad metabólica, tuvo como objetivo evaluar el efecto de la ingesta de fructosa en los niveles de ácido úrico plasmático en sujetos con posibilidad de enfermedad metabólica. La pregunta clínica fue: ¿El consumo de fructosa ejercerá efecto sobre los niveles de ácido úrico plasmático en sujetos con posibilidad de enfermedad metabólica? Se utilizó la metodología Nutrición Basada en Evidencia (NuBE). La búsqueda de información se realizó en Science Direct, Pubmed, Scielo, Bvs encontrando 17 artículos, siendo seleccionados 12 que han sido evaluados por la herramienta para lectura crítica CASPe, seleccionándose finalmente el Ensayo Clínico Aleatorizado titulado como Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial, el cual posee un nivel de evidencia A1 y Grado de Recomendación Fuerte, de acuerdo a la expertise del investigador. El comentario crítico permitió concluir que la ingesta de fructosa aumenta las concentraciones de ácido úrico plasmático en pacientes con posibilidad de enfermedad metabólica.